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Productordered released on bond, p 248 no 256, misbranding of “ziratol ”u s v 936 bottles and 6 jugs of ziratol, consent decree ofcondemnation and forfeiture. Product ordered released on bond, p 260 the bristol-myers company in replying to the council report madeno offer to declare the exact composition of ziratol, to state theactual phenol-coefficient, or to remove the other objections pointedout in the report of the council in other words, the bristol-myerscompany has abandoned a definite but false claim of high germicidalpower-- a claim which subjected the firm to federal prosecution-- andhas substituted therefor indefinite statements which do not define theactual germicidal efficiency of ziratol -- from the journal a m a , oct 6, 1917 gonosan report of the council on pharmacy and chemistrythe council has adopted the following report on gonosan and authorizedits publication w a puckner, secretary gonosan riedel and company, inc , new york city comes in the form ofcapsules, each said to contain 5 minims of a mixture composed of oil ofsandalwood 80 per cent , and 20 per cent of alpha- and beta-resin ofkava, isolated by a patent process the mixture, as the name implies, is intended for the treatment of gonorrhea this proprietary preparation was under consideration by the council atvarious times from 1905 to 1910 during this time, the council agreedto accept the preparation if the suggestive name was changed, thetherapeutic exaggerations abandoned, and the drug kava admitted to newand nonofficial remedies the name was not changed, the other questionswere left open, and the preparation was not accepted recent and more objectionable advertising of gonosan makes it advisablefor the council to take action and to publish a report the tone ofthis advertising is reflected by the following quotation from a recentadvertising circular. “the old-established balsamic treatment of gonorrhea, for essay years neglected in favor of the local injection of organic silver and other germicidal salts, has, with the increasing knowledge and attention paid to the composition and purity of the balsams, regained to a large extent the confidence formerly reposed in them “it may now be said that the combined treatment with local injections and internal administration of natural balsamic products completely dominates modern gonorrheal therapy ”any one conversant with current medical literature and practice wouldstamp these statements as misleading exaggerations the balsams, oleoresins and volatile oils may have essay value as minor adjuvantsin the treatment of gonorrhea, but that is all the position in thisrespect has not changed materially in recent years these agents do nothave a value equal to that of local treatment, as the quoted statementimplies the claims made for gonosan might with equal force be made for oil ofsantal alone kava kava, the other constituent, belongs to the pepperfamily. It had a temporary vogue essay two or three decades ago, but hasfailed to maintain a place it has never been recognized officially there is no scientific evidence that it has any value either alone oras an adjuvant to sandal oil the “clinical reports” quoted in theadvertising circulars, rather curiously, nearly all date back tenyears or more, viz , to a period when the attitude of the professiontoward proprietary remedies was less critical than it is now it wouldbe interesting to know whether these authors still adhere to theiropinion, or whether any of them have subsequently had experiencessimilar to that of a correspondent who wrote:“gonosan, at my hands, did not prove to be of more essentialvalue in the treatment of gonorrhea than any other sandalwood oilpreparation the various claims made for gonosan, that it possessessedative and anesthetic properties, that by its continuous use theurethral discharge disappears more rapidly and that, if combined withappropriate diet and rest, it is liable to prevent complications, are, according to my experience, not corroborated by actual results ”the only experimental work quoted in support of gonosan, that of pohl, is not convincing the doses that pohl found necessary to influenceexperimental purulent pleurisy makes it impossible to transfer his workto the clinic he found a dosage of oil of santal corresponding to anounce per day, for man, inefficient. Positive results were obtainedonly with 2 ounces per day in order to learn the estimate placed on the therapeutic value of the“balsams, ” an inquiry was sent to the authors of the papers presentedto the section of genito-urinary diseases at the recent meeting of theamerican medical association in new york the inquiry read:“dear doctor:-- an advertising circular for gonosan ‘riedel’ which isnow being distributed begins thus. ‘the old-established balsamic treatment of gonorrhea, for essay years neglected in favor of the local injection of organic silver and other germicidal salts, has, with the increasing knowledge and attention paid to the composition and purity of the balsams, regained to a large extent the confidence formerly reposed in them ’ ‘it may now be said that the combined treatment with local injections and internal administration of natural balsamic products completely dominates modern gonorrheal therapy ’“is the statement correct that the combined treatment with localinjections and internal administration of natural balsamic productscompletely dominates modern gonorrheal therapy?. your reply to the abovewill be appreciated by the council ”seventeen replies were received they bear out the position thathas been outlined only one writer considered the statement evenapproximately justified, and this in the sense that “the majorityof paper receive no other treatment” than a combination of localapplications and systemic medication another stated that, “in ageneral way their statement is true though a trifle too sweeping, ” andthen added that the field of the balsams is rather restricted withthe exception of these qualified endorsements the remaining fifteenreplies characterized the statement as incorrect and misleading thereplies are a valuable contribution to the status of the “balsam”treatment of gonorrhea, and extracts of them are appended to thisreport it is recommended that the council declare gonosan inadmissible tonew and nonofficial remedies, because the therapeutic claims areexaggerated rule 6. Because there is no evidence that the combinationof kava resin with oil of santal is superior to oil of santal alone rule 10.

But the other two are more rare, and hardto be met with, yet they are both found growing wild about appledore, near rye in kent time they flower not usually until august government and virtues the plant is venereal, pleasing, andharmless the herb or the root all that the devil hath left of itbeing boiled in wine, and drank, write my paper mla format is very powerful against the plague, and all pestilential diseases or fevers, poisons also, and the bitingsof venemous beasts. It helps also those that are inwardly bruised byany casuality, or outwardly by falls or blows, dissolving the clottedblood. And the herb or root beaten and outwardly applied, takes awaythe black and blue marks that remain in the skin the decoction ofthe herb, with honey of roses put therein, is very effectual to helpthe inveterate tumours and swellings of the almonds and throat, byoften gargling the mouth therewith it helps also to procure womencourses, and eases all pains of the mother and to break and discusswind therein, and in the bowels the powder of the root taken in drink, drives forth the worms in the body the juice or distilled water ofthe herb, is effectual for green wounds, or old sores, and cleansesthe body inwardly, and the seed outwardly, from sores, scurf, itch, pimples, freckles, morphew, or other deformities thereof, especiallyif a little vitriol be dissolved therein dock thesis kinds of these are so well known, that i shall not trouble youwith a description of them. My book grows big too fast government and virtues all docks are under jupiter, of which thered dock, which is commonly called bloodwort, cleanses the blood, andstrengthens the liver. But the yellow dock-root is best to be takenwhen either the blood or liver is affected by choler all of themhave a kind of cooling but not all alike drying quality, the sorrelbeing most cold, and the blood-worts most drying of the burdock, ihave spoken already by itself the seed of most of the other kinds, whether the gardens or fields, do stay lasks and fluxes of all sorts, the loathing of the stomach through choler, and is helpful for thosethat spit blood the roots boiled in vinegar help the itch, scabs, andbreaking out of the skin, if it be bathed therewith the distilledwater of the herb and roots have the same virtue, and cleanses the skinfrom freckles, morphews, and all other spots and discolourings therein all docks being boiled with meat, make it boil the sooner. Besidesblood-wort is exceeding strengthening to the liver, and procures goodblood, being as wholeessay a pot herb as any growing in a garden. Yetsuch is the nicety of our times, forsooth, that women will not put itinto a pot, because it makes the pottage black.

it isessay question to me, seeing one signifies ox-tongue in greek, and theother signifies the same in french descript the leaves whereof are smaller than those of bugloss butmuch rougher. The stalks rising up about a foot and a half high, and ismost commonly of a red colour. The flowers stand in scaly round heads, being composed of thesis small yellow flowers not much unlike to thoseof dandelion, and the seed flieth away in down as that doth. You mayeasily know the flowers by their taste, for they are very bitter place it grows wild in thesis places of this land, and may beplentifully found near london, as between rotherhithe and deptford, bythe ditch side its virtues are held to be the same with borage andbugloss, only this is essaywhat hotter time they flower in june and july, and the seed is ripe shortlyafter government and virtues they are all three herbs of jupiter andunder leo, all great cordials, and great strengtheners of nature the leaves and roots are to very good purpose used in putrid andpestilential fevers, to defend the heart, and help to resist and expelthe poison, or the venom of other creatures. The seed is of the likeeffect. And the seed and leaves are good to increase milk in womenbreasts. The leaves, flowers, and seed, all or any of them, are good toexpel pensiveness and melancholy. It helps to clarify the blood, andmitigate heat in fevers the juice made into a syrup prevails much toall the purposes aforesaid, and is put, with other cooling, opening andcleansing herbs to open obstructions, and help the yellow jaundice, andmixed with fumitory, to cool, cleanse, and temper the blood thereby;it helps the itch, ringworms and tetters, or other spreading scabs orsores the flowers candied or made into a conserve, are helpful in theformer paper, but are chiefly used as a cordial, and are good for thosethat are weak in long sickness, and to comfort the heart and spiritsof those that are in a consumption, or troubled with often swoonings, or passions of the heart the distilled water is no less effectual toall the purposes aforesaid, and helps the redness and inflammations ofthe eyes, being washed therewith. The herb dried is never used, butthe green. Yet the ashes thereof boiled in mead, or honied water, isavailable against the inflammations and ulcers in the mouth or throat, to gargle it therewith. The roots of bugloss are effectual, being madeinto a licking electuary for the cough, and to condensate thick phlegm, and the rheumatic distillations upon the lungs blue-bottle it is called syanus, i suppose from the colour of it. Hurt-sickle, because it turns the edge of the sickles that reap the corn. Blue-blow, corn-flower, and blue-bottle descript i shall only describe that which is commonest, and inmy opinion most useful. Its leaves spread upon the ground, beingof a whitish green colour, essaywhat on the edges like those ofcorn-scabious, amongst which rises up a stalk divided into diversbranches, beset with long leaves of a greenish colour, either but verylittle indented, or not at all. The flowers are of a blueish colour, from whence it took its name, consisting of an innumerable company offlowers set in a scaly head, not much unlike those of knap-weed. Theseed is smooth, bright, and shining, wrapped up in a woolly mantle.

It provokes sweatingabundantly, and in this or any other sweating medicine, write my paper mla format order your bodythus. Take it in bed, and cover yourself warm, in your sweating, drinkposset-drink as hot as you can, if it be for a fever, boil sorrel andred sage in posset-drink, sweat an hour or two if your strength willbear it, then the chamber being kept very warm, shift yourself all butyour head, about which your cap which you sweat in being kept on wrapa hot napkin, which will be a means to repel the vapours back this ihold the best method for sweating in fevers and pestilences, in whichthis electuary is very good i am very loth to leave out this medicine, which if it were stretched out, and cut in thongs, would reach roundthe world requies nicholaus college take of red rose leaves, the whites being cut off, blueviolets, of each three drams, opium of thebes, dissolved in wine, the seeds of white henbane, poppies white and black, the roots ofmandrakes, the seeds of endive, purslain, garden lettuce, psyllium, spodium, gum tragacanth, of each two scruples and five grains, nutmegs, cinnamon, ginger, of each a dram and an half, sanders, yellow, white, and red, of each a dram and an half, sugar three times their weight, dissolved in rose-water. Mix them together, and make of them anelectuary according to art culpeper i like not the receipt taken inwardly electuarium reginæ coloniens college take of the seeds of saxifrage and gromwell, juice ofliquorice, of each half an ounce, the seeds of caraway, annis, smallage, fennel, parsley of macedonia, broom, carrots, bruscus, asparagus, lovage, cummin, juniper, rue, siler mountain, the seeds ofacorus, pennyroyal, cinquefoyl, bayberries, of each two drams, indianspikenard, schœnanth, amber, valerian, hog fennel, lapis lincis, ofeach a dram and an half, galanga, ginger, turbith, of each two drams, sena an ounce, goat blood prepared half an ounce, mix them together:first beat them into powder, then make them into an electuary accordingto art, with three times their weight in sugar dissolved in white wine culpeper it is an excellent remedy for the stone and wind cholic, adram of it taken every morning. I assure such as are troubled with suchdiseases, i commend it to them as a jewel pills culpeper pills in greek are called, katopotia, in latin, pilulæ. Which signifies little balls, because they are made up insuch a form, that they may be the better swallowed down, by reason ofthe offensiveness of their taste pilulæ de agarico or pills of agarick college take of agarick three drams, our own blue orris roots, mastich, horehound, of each one dram, turbith five drams, specieshiera picra half an ounce, colocynthis, sarcocol, of each two drams, myrrh one dram, sapa as much as is sufficient to make it into a massaccording to art culpeper it was invented to cleanse the breast and lungs of flegm, it works pretty strongly half a dram at a time keeping yourselfwarm, cannot well do you harm, unless your body be very weak pilulæ aggregativæ college take of citron, myrobalans, rhubarb, of each half anounce, juice of agrimony and wormwood made thick, of each two drams, diagridium five drams, agarick, colocynthis, polypodium of each twodrams, turbith, aloes, of each six drams, mastich, red roses, sal gem epithymum, annis, ginger, of each a dram, with syrup of damask roses, make it into a mass according to art culpeper it purges the head of choler, flegm and melancholy, andthat stoutly. It is good against quotidian agues, and faults in thestomach and liver, yet because it is well corrected if you take buthalf a dram at a time, and keep yourself warm, i suppose you may takeit without danger pilulæ alœphanginæ college take of cinnamon, cloves, cardamoms the less, nutmegs, mace, calamus aromaticus, carpobalsamum, or juniper berries, squinanth, wood of aloes, yellow sanders, red roses dried, wormwood, of each halfan ounce, let the tincture be taken out of these, being grossly bruisedin spirit of wine, the vessel being close stopped. In three pounds ofthis tincture, being strained, dissolve aloes one pound, which beingdissolved, add mastich, myrrh, of each half an ounce, saffron twodrams, balsam of peru one dram, the superfluous liquor being consumed, either over hot ashes, or a bath, bring it into a mass of pills culpeper it cleanses both stomach and brain of gross and putrifiedhumours, and sets the senses free when they are thereby troubled, itcleanses the brain offended by ill humours, wind, &c helps vertigo andhead-aches, and strengthens the brain exceedingly, helps concoction, and strengthens the stomach, one dram taken at night going to bed, will work gently next day. If the writingy be weak, you may give less, ifstrong more if you take but half a dram, you may go abroad the nextday. But if you take a dram, you may keep the house. There can be noharm in that pilulæ de aloe lota or pills of washed aloes college take of aloes washed with juice of red roses, one ounce, agarick three drams, mastich two drams, diamoscu dulce half a dram, syrup of damask-roses, so much as is sufficient to make it into a massaccording to art culpeper it purges both brain, stomach, bowels, and eyes ofputrified humours, and also strengthens them use these as thesucceeding aloe rosata college take of aloes in powder four ounces, juice of damask rosesclarified one pound, mix them and digest them in the sun, or in a bath, till the superfluous liquor be drawn off, digest it, and evaporate itfour times over, and keep the mass culpeper it is a gallant gentle purger of choler, frees the stomachfrom superfluous humours, opens stoppings, and other infirmities ofthe body proceeding from choler and flegm, as yellow jaundice, &c andstrengthens the body exceedingly take a scruple, or half a dram atnight going to bed, you may walk abroad, for it will hardly work tillnext day in the afternoon pilulæ aureæ college take of aloes, diacrydium, of each five drams, red roses, smallage seeds, of each two drams and an half, the seeds of annisand fennel, of each one dram and an half, mastich, saffron, troch, alhandal, of each one dram, with a sufficient quantity of honey roses, make it into a mass according to art culpeper they are held to purge the head, to quicken the senses, especially the sight, and to expel wind from the bowels, but worksessaything harshly half a dram is the utmost dose, keep the fire, takethem in the morning, and sleep after them, they will work before noon pilulæ cochiæ, the greater college take of species, hiera picra, ten drams, troch, alhandal, three drams and an half, diacrydium two drams and an half, turbith, stœchas, of each five drams, with a sufficient quantity of syrup ofstœchas, make it into a mass, according to art culpeper it is held to purge the head, but it is but a dogged purgeat best, and must be given only to strong bodies, and but half a dramat a time, and yet with great care pilulæ cochiæ, the less college take of aloes, scammony, colocynthis, of each one ounce, with equal writings of syrup of wormwood, and of purging thorn, make itinto a mass according to art pilulæ de cynoglosso or pills of hound-tongue college take of the roots of hound-tongue dried, white henbaneseed, opium prepared, of each half an ounce, myrrh six drams, olibanumfive drams, saffron, castoreum, styrax, calamitis, of each one dram andan half, with syrup of stœchas, make it into a mass culpeper it stays hot rheums that fall down upon the lungs, therefore is good in phthisics, also it mitigates pain, a scruple isenough to take at a time going to bed, and too much if your body beweak. Have a care of opiates for fear they make you sleep your last pilulæ ex duobus or pills of two things college take of colocynthis, and scamony, of each one ounce, oil ofcloves as much as is sufficient to malax them well, then with a littlesyrup of purging thorn, make it into a mass pilulæ de eupatorio or pills of eupatorium college take of the juice of maudlin, and wormwood made thick, citron, myrobalans, of each three drams, rhubarb three drams and anhalf, mastich one dram, aloes five drams, saffron half a dram, syrup ofthe juice of endive, as much as is sufficient to make it into a mass culpeper it is a gallant gentle purge, and strengthening, fittedfor such bodies as are much weakened by disease of choler the authorappropriates it to such as have tertian agues, the yellow jaundice, obstructions or stoppings of the liver. Half a dram taken at nightgoing to bed, will work with an ordinary body, the next day by noon pilulæ fætidæ or stinking pills college take of aloes, colocynthis, ammoniacum, sagapen, myrrh, rue-seeds, epithymum, of each five drams, scamony three drams, theroots of turbith half an ounce, the roots of spurge the less prepared, hermodactils of each two drams, ginger one dram and an half, spikenard, cinnamon, saffron, castoreum, of each one dram, euphorbium prepared twoscruples, dissolve the gums in juice of leeks, and with syrup made withthe juice of leeks and sugar, make it into a mass culpeper they purge gross and raw flegm, and diseases thereofarising. Gouts of all sorts, pains in the back-bone, and other joints:it is good against leprosies, and other such like infirmities of theskin i fancy not the receipt much pilulæ de hermodactilis or pills of hermodactils college take of sagapen six drams, opopanax three drams, melt themin warm juice of coleworts, so much as is sufficient, then strain itthrough a convenient rag, afterwards boil it to a mean thickness, thentake of hermodactils, aloes, citron, myrobalans, turbith, coloquintida, soft bdellium, of each six drams, euphorbium prepared, the seeds of rueand smallage, castoreum, sarcocol, of each three drams, saffron onedram and an half, with the syrup of the juice of coleworts made withhoney, make it into a mass according to art culpeper they are good against the gout, and other cold afflictionsof the joints these are more moderate by half than pilulæ fœtidæ, and appropriated to the same diseases pilulæ de hiera cum agarico or pills of hiera with agarick college take of species hiera picra, agarick, of each half anounce, aloes one ounce, honey roses so much as is sufficient to make itinto a mass according to art pilulæ imperiales or imperial pills college take of aloes two ounces, rhubarb one ounce and an half, agarick, sena, of each one ounce, cinnamon three drams, ginger twodrams, nutmegs, cloves, spikenard, mastich, of each one dram with syrupof violets, make it into a mass according to art culpeper it cleanses the body of mixt humours, and strengthens thestomach exceedingly, as also the bowels, liver, and natural spirits. Itis good for cold natures, and cheers the spirits the dose is a scrupleor half a dram, taken at night pilulæ de lapide lazuli or pills of lapis lazuli college take of lapis lazuli in powder and well washed, five drams, epithymum, polypodium, agarick, of each an ounce, scamony, blackhellebore roots, sal gem of each two drams and an half, cloves, annisseeds, of each half an ounce, species hiera simple fifteen drams, withsyrup of the juice of fumitory, make it into a mass according to art culpeper it purges melancholy very violently pilulæ macri college take of aloes two ounces, mastich half an ounce, driedmarjoram two drams, salt of wormwood one dram, make them all, being inpowder, into a mass according to art with juice of coleworts and sugar, so much as is sufficient culpeper it strengthens both stomach and brain, especially thenerves and muscles, and eases them of such humours as afflict them, andhinder the motion of the body, they open obstructions of the liver andspleen, and takes away diseases thence coming pilulæ mastichinæ or mastich pills college take of mastich two ounces, aloes four ounces, agarick, species hiera simple, of each one ounce and an half, with syrup ofwormwood, make it into a mass according to art culpeper they purge very gently, but strengthen much, both head, brain, eyes, belly, and reins pilulæ mechoacanæ or pills of mechoacan college take of mechoacan roots half an ounce, turbith threedrams, the leaves of spurge steeped in vinegar and dried, the seedsof walwort, agarick trochiscated, of each two drams, spurge rootsprepared, mastich, of each one dram and an half, mace, cinnamon, sal gem of each two scruples, beat them into powder, and with white wine, bring them into a mass when it is dry, beat it into powder, and withsyrup made with the juice of orris roots and sugar, make it the secondtime into a mass for pills culpeper they purge flegm very violently pilulæ de opopanace or pills of opopanax college take of opopanax, sagapen, bdellium, ammoniacum, hermodactils, coloquintida, of each five drams, saffron, castoreum, myrrh, ginger, white pepper, cassia lignea, citron, myrobalans, of eachone dram, scamony two drams, turbith half an ounce, aloes an ounce andan half, the gums being dissolved in clarified juice of coleworts, with syrup of the juice of coleworts, make them into a mass accordingto art culpeper it helps tremblings, palsies, gouts of all sorts, cleanses the joints, and is helpful for such as are troubled with coldafflictions of the nerves it works violently pilulæ rudii college take of coloquintida six drams, agarick, scamony, the rootsof black hellebore, and turbith, of each half an ounce, aloes oneounce, diarrhodon abbatis half an ounce, let all of them the diarrh abbatis excepted be grossly bruised, and infused eight days in thebest spirits of wine in a vessel close stopped, in the sun, so that theliquor may swim at top the breadth of six fingers.

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Cools the blood, quenches thirst, breeds milk, and is good for choleric bodies, and suchas have a frenzy, or are frantic it is more wholeessay eaten boiledthan raw logabus, herba leporina a kind of trefoil growing in france andspain let them that live there look after the virtues of it lavendula lavender. Hot and dry in the third degree. The templesand forehead bathed with the juice of it. As also the smell of theherb helps swoonings, catalepsis, falling-sickness, provided it be notaccompanied with a fever see the flowers laureola laurel the leaves purge upward and downward. They are goodfor rheumatic people to chew in their mouths, for they draw forth muchwater laurus bay-tree the leaves are hot and dry, resist drunkenness, they gently bind and help diseases in the bladder, help the stinging ofbees and wasps, mitigate the pain of the stomach, dry and heal, openobstructions of the liver and spleen, resist the pestilence lappa minor the lesser burdock lentiscus mastich-tree both the leaves and bark of it stop fluxes being hot and dry in the second degree spitting and evacuations ofblood, and the falling out of the fundament lens palustris duckmeat. Cold and moist in the second degree, helpsinflammations, hot swellings, and the falling out of the fundament, being warmed and applied to the place lepidium piperites dittander, pepperwort, or scar-wort. A hot fierysharp herb, admirable for the gout being applied to the place. Beingonly held in the hand, it helps the tooth-ache, and withall leaves awan colour in the hand that holds it livisticum lovage clears the sight, takes away redness and frecklesfrom the face libanotis coronaria see rosemary linaria toad-flax, or wild-flax. Hot and dry, cleanses the reins andbladder, provokes urine, opens the stoppings of the liver and spleen, and helps diseases coming thereof. Outwardly it takes away yellownessand deformity of the skin lillium convallium lilly of the valley see the flowers lingua cervina hart-tongue.