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This brings up a number of interesting questions to be considered inmedical jurisprudence there is probably no condition so common as thatthe injury is admitted, but death is attributed to essay other cause thus if there are several wounds it may be hard to decide on therelative degree of mortality of any writingicular one, so as to be able tosay that death was directly or necessarily due to this or that one thedefence may plead that death was not necessarily due to the writingicularwound attributed to the prisoner this brings up the question which of two or more wounds was the cause of death?. no generalrule can be laid down for all paper, but each case must be judgedby itself another way of putting the question is. “which of two ormore wounds was mortal?. ” the questions are not quite synonymous, fortwo or more of the wounds might be “mortal” but not equally the causeof death in fact, as we have already seen, no one of the wounds ifthey are multiple may be of itself mortal, but taken together theyare so consequently we will suppose that there are but two wounds, and not multiple ones, and the question remains which of these woundswas the cause of death a wound may be said to be of itself mortalwhen it is the cause of death directly or indirectly in spite of thebest medical assistance in essay continental states mortal wounds aredivided into two classes, those absolutely and those conditionallymortal, the former including those in which the best medical assistanceis at hand, sent for or timely rendered without everting the result the mortal result in the second class is conditional on want oftreatment, improper treatment, or accidental circumstances as taylorsays, it is better to look at the effect of the wound and the intentof the assailant, as is done in english law, rather than at accidentalrelations of the wound to return to the question, we can readily imagine that a man mayreceive two wounds at different times or from different persons, anddie after the second wound taylor629 mentions the following casein which the question arose as to which of two injuries caused death:in reg v foreman c c c february, 1873 the prisoner had struckthe deceased essay severe blows on the head a fortnight later, havingwritingially recovered, another man gave him essay severe blows on thehead a fortnight later still he had left hemiplegia, and died a fewdays later of a large abscess in the brain the question arose whichset of blows had been the cause of the abscess the prisoner, thefirst assailant, was acquitted, as the deceased had had no serioussymptoms until the second assault, and there was no satisfactorymedical evidence as to the relation of the two assaults to the abscessformation the same author also supposes the following case. A manhaving received a gunshot wound of the shoulder is doing well, whenin another quarrel he receives a penetrating stab-wound of the thoraxand abdomen he dies after lingering for a time, under the effectsof these wounds if the wound of the shoulder could be proven to bethe cause of death, the second assailant could not be convicted ofmanslaughter, and so too with the first assailant if it could be shownthat the victim died of the stab-wound it might be possible for asurgeon to decide the question definitely at once if death occurredsoon after the stab, which was found to have penetrated the heart, alarge blood-vessel, or one of the viscera. Or, on the other hand, ifthe stab-wound was found to be superficial and not penetrating, and thewound in the shoulder had suppurated and caused septicæmia in either or any case, everything would depend upon the evidencefurnished by the medical witness his knowledge and judgment arerequired to distinguish the guilty from the innocent again, essaytimes death may appear to be equally the result of eitheror both wounds, in which case, as far as the medical evidence goes, both assailants would be liable to the charge of manslaughter or thesecond wound may be accidental or suicidal, and again the questionwould arise as to the cause of death a case illustrating this istold by taylor630 substantially as follows. A grocer assistantpursued a thief, who had stolen from a cart, into a coal-shed, wherehe was stabbed twice in the abdomen the larger wound suppurated, the smaller wound healed up, and the man died of peritonitis onpost-mortem examination the suppurating wound was found not to involvea vital writing, while the small healed wound had wounded the liverand gall bladder and had set up the fatal peritonitis the largesuppurating wound had apparently been inflicted purposely. The fatalwound, directed upward and backward, might have been accidental by thedeceased rushing upon the knife held more or less in self-defence thecase never came to trial, as the assailant was never found, but it canbe readily imagined what complications might have arisen furthermore, the wounded person may have taken poison or beensubsequently ill-treated, and he may have died from these causes ratherthan the injury but the question arises as to whether the woundwas necessarily the cause of death here, in order to exculpate theassailant, the supervening disease or maltreatment must be such as toaccount for sudden or rapid death under the symptoms which actuallypreceded death was death due to natural causes?.

“castanea, fresh leaves, 40 gr. Passiflora, fresh plant, 40 gr. Gelsemium, green tincture, 8 minims. Inula, represented by the camphoraceous stearoptene helenin, 20 grs. Iodized lime, 8 grs. Menthol, 1-4 grs. Aromatic syrup yerba santa, 60 minims ”it is said to be. “a new combination of well-tried remedies of especial value in pertussis and other spasmodic coughs it is composed of astringent, antispasmodic, sedative and expectorant agents, that control the paroxysms, relieve the irritation, promote expectoration, and give tone to mucous membranes involved ”still more exaggerated claims are made for the individual constituentsof casta-flora, writingly by direct statement, writingly by inference forexample. “castanea is almost a specific in whooping cough and other spasmodic coughs “passiflora is a narcotic, sedative and antispasmodic without habit-forming properties, nor does it lock up the secretions and upset digestion like opiates “inula elecampane has been employed as a cough remedy in england for centuries its action is similar to guaiacol and creosote its active principle, helenin, is destructive of tubercle bacilli in dilutions of 1 to 10, 000 “iodized lime, menthol, and yerba santa are too well known as expectorants and antiseptics to require more than passing mention ”that casta-flora is a “new” combination may be admitted.

Lyon thesis, 1883, no 188, p 72 - boy, age 16, hunghimself. Rope broke. He was resuscitated. Reddish circular furrow onneck, not like parchment. He had erection and ejaculation. Buzzing inhis ears and flashes before his eyes 13 lacassagne.

They also help ulcersin the breast and lungs the dose is from ten grains to a scruple trochisci cypheos, for mithridate college take of pulp of raisins of the sun, cypress, turpentine, of each three ounces, myrrh, squinanth, of each an ounce and an half, cinnamon half an ounce, calamus aromaticus nine drams, the roots ofround cypress, and indian spikenard, cassia lignea, juniper berries, bdellium, aspalthus or wood of aloes, two drams and an half, saffronone dram, clarified honey as much as is sufficient, canary wine alittle. Let the myrrh and bdellium be ground in a mortar with the wine, to the thickness of liquid honey, then add the turpentine, then thepulp of raisins, then the powders. At last with the honey, let them allbe made into troches culpeper it is excellently good against inward ulcers in what writingof the body soever they be it is chiefly used in compositions, astreacle and mithridate trochisci de eupatorio or troches of maudlin college take of the juice of maudlin made thick, manna, of eachan ounce, red roses half an ounce, spodium three drams and an half, spikenard three drams, rhubarb, asarabacca roots, annis seeds, of eachtwo drams let the nard, annis seeds, and roses, be beaten together, the spodium, asarabacca, and rhubarb by themselves, then mix the mannaand juice of maudlin in a mortar, add the powders, and with new juicemake it into troches culpeper obstructions, or stoppings, and swelling above nature, both of the liver and spleen, are cured by the inward taking of thesetroches, and diseases thereof coming, as yellow and black jaundice, thebeginning of dropsies, &c troches of gallia moschata college take of wood of aloes five drams, ambergris three drams, musk one dram, with mussilage of gum tragacanth made in rose water, make it into troches according to art culpeper they strengthen the brain and heart, and by consequenceboth vital and animal spirits, and cause a sweet breath they are of anextreme price, therefore i pass by the dose trochisci gordonii college take of the four greater cold seeds husked, the seedsof white poppies, mallows, cotton, purslain, quinces, mirtles, gumtragacanth, and arabic, fistic-nuts, pine-nuts, sugar-candy, penids, liquorice, french-barley, mussilage of fleawort seeds, sweet almondsblanched, of each two drams, bole-ammoniac, dragon-blood, spodium, red roses, myrrh, of each half an ounce, with a sufficient quantity ofhydromel, make it into troches according to art culpeper they are held to be very good in ulcers of the bladder, and all other inward ulcers whatsoever, and ease fevers coming thereby, being of a fine cooling, slippery heating nature trochisci hedichroi, galen for treacle college take of aspalthus, or yellow sanders, the leaves ofmastich, the roots of asarabacca, of each two drams, rhupontic, castus, calamus aromaticus, wood of aloes, cinnamon, squinanth, opobalsamumor oil of nutmegs by expression, of each three drams, cassia lignea, indian leaf or mace, indian spikenard, myrrh, saffron, of each sixdrams, amomus, or cardamoms the less, an ounce and an half, mastich adram, canary wine as much as is sufficient let the myrrh be dissolvedin the wine, then add the mastich and saffron well beaten, then theopobalsamum, then the rest in powder, and with the wine, make them upinto troches, and dry them gently culpeper they are very seldom or never used but in othercompositions, yet naturally they heat cold stomachs, help digestion, strengthen the heart and brain trochisci hysterici college take of asafœtida, galbanum, of each two drams and an half, myrrh two drams, castoreum a dram and an half, the roots of asarabaccaand long birthwort, the leaves of savin, featherfew, nep, of each onedram, dittany half a dram, with either the juice or decoction of rue, make it into troches according to art culpeper these are applied to the fœminine gender, help fits of themother, expel both birth and after-birth, cleanse women after labour, and expel the relics of a careless midwife trochisci de ligno aloes or troches of wood of aloes college take of wood of aloes, red roses, of each two drams, mastich, cinnamon, cloves, indian spikenard, nutmegs, parsnip seed, cardamoms the greater and lesser, cubebs, gallia moschata, citronpills, mace, of each one dram and an half, ambergris, musk, of eachhalf a scruple, with honey of raisins make it into troches culpeper it strengthens the heart, stomach, and liver, takes awayheart-qualms, faintings, and stinking breath, and resists the dropsy trochisci e mirrha or troches of myrrh college take of myrrh three drams, the meal of lupines five drams, madder roots, the leaves of rue, wild mints, dittany of crete, cumminseeds, asafœtida, sagapen, opopanax, of each two drams, dissolve thegums in wine wherein mugwort hath been boiled, or else juniper-berries, then add the rest, and with juice of mugwort, make it into trochesaccording to art culpeper they provoke the menses, and that with great ease tosuch as have them come down with pain take a dram of them beateninto powder, in a spoonful or two of syrup of mugwort, or any othercomposition tending to the same purpose sief de plumbo or sief of lead college take of lead burnt and washed, brass burnt, antimony, tuttywashed, gum arabic and tragacanth of each an ounce, opium half a dram, with rose-water, make them, being beaten and sifted, into troches trochisci polyidæ androm college take of pomegranate flowers twelve drams, roach album threedrams, frankincense, myrrh, of each half an ounce, chalcanthum twodrams, bull gall six drams, aloes an ounce, with austere wine, orjuice of nightshade or plantain, make them into troches according toart culpeper they are very good they say, being outwardly applied, bothin green wounds and ulcers i fancy them not trochisci de rhubarbaro or troches of rhubarb college take of rhubarb ten drams, juice of maudlin made thick, bitter almonds, of each half an ounce, red roses three drams, theroots of asarabacca, madder, indian spikenard, the leaves of wormwood, the seeds of annis and smallage, of each one dram, with wine in whichwormwood hath been boiled, make them into troches according to art culpeper they gently cleanse the liver, help the yellow jaundice, and other diseases coming of choler and stoppage of the liver trochisci de santalis or troches of sanders college take of the three sanders, of each one ounce, the seeds ofcucumbers, gourds, citruls, purslain, spodium, of each half an ounce, red roses seven drams, juice of barberries six drams, bole-ammoniachalf an ounce, camphire one dram, with purslain water make it intotroches culpeper the virtues are the same with troches of spodium, both ofthem harmless trochisci da scilla ad theriacam or troches of squils, for treacle college take a squil gathered about the beginning of july, of amiddle bigness, and the hard writing to which the small roots stick, wrapit up in paste, and bake it in an oven, till the paste be dry, and thesquil tender, which you may know by piercing it with a wooden skewer, or a bodkin, then take it out and bruise it in a mortar, adding toevery pound of the squil, eight ounces of white orobus, or red cicersin powder, then make it into troches, of the weight of two drams apiece, your hands being anointed with oil of roses dry them on thetop of the house, opening towards the south, in the shadow, oftenturning them till they be well dry, then keep them in a pewter or glassvessel troches of spodium college take of red roses twelve drams, spodium ten drams, sorrelseed six drams, the seeds of purslain and coriander, steeped in vinegarand dried, pulp of sumach, of each two drams and an half, white starchroasted, balaustines, barberries, of each two drams, gum arabic roastedone dram and an half, with juice of unripe grapes, make it into troches culpeper they are of a fine cooling binding nature, excellent infevers coming of choler, especially if they be accompanied with alooseness, they also quench thirst trochisci de terra lemnia or troches of earth of lemnos college take of earth of lemnos, bole-ammoniac, acacia, hypocystis, gum arabic toasted, dragon blood, white starch, red roses, roseseeds, lap hematitis, red coral, amber, balaustines, spodium, purslainseeds a little toasted, olibanum, hart-horn burnt, cypress nuts, saffron of each two drams, black poppy seeds, tragacanth, pearls, ofeach one dram and an half, opium prepared one dram, with juice ofplantain, make it into troches sief de thure or sief of frankincense college take of frankincense, lap calaminaris, pompholix, of eachten drams, cyrus forty drams, gum arabic, opium, of each six drams, with fair water make it into balls. Dry them and keep them for use trochisci e violis solutivi or troches of violets solutive college take of violet flowers meanly dry, six drams, turbith oneounce and an half, juice of liquorice, scammony, manna, of each twodrams, with syrup of violets, make it into troches culpeper they are not worth talking of, much less worth cost, thecost and labour of making trochisci de vipera ad theriacum or troches of vipers, for treacle college take of the flesh of vipers, the skin, entrails, head, fat, and tail being taken away, boiled in water with dill, and alittle salt, eight ounces, white bread twice baked, grated and sifted, two ounces, make it into troches, your hands being anointed withopobalsamum, or oil of nutmegs by expression, dry them upon a sieveturned the bottom upwards in an open place, often turning them tillthey are well dried, then put them in a glass or stone pot glazed, stopped close, they will keep a year, yet is it far better to maketreacle, not long after you have made them culpeper they expel poison, and are excellently good, by a certainsympathetical virtue, for such as are bitten by an adder trochisci de agno casto or troches of agnus castus college take of the seeds of agnus castus, lettuce, red roseflowers, balaustins, of each a dram, ivory, white amber, bole-ammoniacwashed in knotgrass water two drams, plantain seeds four scruples, sassafras two scruples, with mussilage of quince seeds, extracted inwater of water-lily flowers, let them be made into troches culpeper very pretty troches and good for little trochisci alexiterii renodæus college take of the roots of gentian, tormentil, orris florentine, zedoary, of each two drams, cinnamon, cloves, mace, of each half adram, angelica roots three drams, coriander seeds prepared, roses, ofeach one dram, dried citron pills two drams, beat them all into powder, and with juice of liquorice softened in hippocras, six ounces, makethem into soft paste, which you may form into either troches or smallrolls, which you please culpeper it preserves and strengthens the heart exceedingly, helpsfaintings and failings of the vital spirits, resists poison and thepestilence, and is an excellent medicine for such to carry about themwhose occasions are to travel in pestilential places and corrupt air, only taking a very small quantity now and then troches of annis seed mesue college take of annis seeds, the juice of maudlin made thick, ofeach two drams, the seeds of dill, spikenard, mastich, indian leaf ormace, the leaves of wormwood, asarabacca, smallage, bitter almonds, of each half a dram, aloes two drams, juice of wormwood so much as issufficient to make it into troches according to art culpeper they open obstructions of the liver, and that very gently, and therefore diseases coming thereof, help quartan agues you canscarce do amiss in taking them if they please but your palate trochisci diarhodon mesue college take of the flowers of red roses six drams, spikenard, woodof aloes, of each two drams, liquorice three drams, spodium one dram, saffron half a dram, mastich two drams, make them up into troches withwhite wine according to art culpeper they wonderfully ease fevers coming of flegm, as quotidianfevers, agues, epiatos, &c pains in the belly trochisci de lacca mesue college take of gum lacca cleansed, the juice of liquorice, maudlin, wormwood, and barberries, all made thick, rhubarb, longbirthwort, costus, asarabacca, bitter almonds, madder, annis, smallage, schænanth, of each one dram, with the decoction of birthwort, schænanth, or the juice of maudlin, or wormwood, make them into trochesaccording to art culpeper it helps stoppings of the liver and spleen, and feversthence coming, it expels wind, purges by urine, and resists dropsies pastilli adronis galen college take of pomegranate flowers ten drams, copperas twelvedrams, unripe galls, birthwort, frankincense, of each an ounce, alum, myrrh, of each half an ounce, misy two drams, with eighteen ounces ofaustere wine, make it into troches according to art culpeper this also is appropriated to wounds, ulcers, and fistulas, it clears the ears, and represses all excressences of flesh, cleansesthe filth of the bones trochisci musæ galen college take of alum, aloes, copperas, myrrh, of each six drams, crocomagma, saffron, of each three drams, pomegranate flowers half anounce, wine and honey, of each so much as is sufficient to make it upinto troches according to art culpeper their use is the same with the former crocomagma of damocrates galen college take of saffron an hundred drams, red roses, myrrh, of eachfifty drams, white starch, gum, of each thirty drams, wine, so much asis sufficient to make it into troches culpeper it is very expulsive, heats and strengthens the heart andstomach trochisci ramich mesue college take of the juice of sorrel sixteen ounces, red roseleaves, an ounce, myrtle berries two ounces, boil them a littletogether, and strain them, add to the decoction, galls well beaten, three ounces, boil them again a little, then put in these followingthings, in fine powder. Take of red roses an ounce, yellow sanders, ten drams, gum arabic an ounce and an half, sumach, spodium, of eachan ounce, myrtle berries four ounces, wood of aloes, cloves, mace, nutmegs, of each half an ounce, sour grapes seven drams, mix them alltogether, and let them dry upon a stone, and grind them again intopowder, and make them into small troches with one dram of camphire, and so much rose water as is sufficient, and perfume them with fifteengrains of musk culpeper they strengthen the stomach, heart, and liver, as also thebowels, they help the cholic, and fluxes of blood, as also bleedingat the nose if you snuff up the powder of them, disburden the body ofsalt, fretting, choleric humours you may carry them about you, andtake them at your pleasure troches of roses mesue college take of red roses half an ounce, wood of aloes twodrams, mastich, a dram and an half, roman wormwood, cinnamon, indianspikenard, cassia lignea, schœnanth, of each one dram, old wine, anddecoction of the five opening roots, so much as is sufficient to makeit into troches according to art culpeper they help pains in the stomach, and indigestion, theilliac passion, hectic fevers, and dropsies, in the beginning, andcause a good colour trochisci diacorallion galen college take of bole-ammoniac, red coral, of each an ounce, balaustines, terra lemnia, white starch, of each half an ounce, hypocistis, the seeds of henbane, opium, of each two drams, juice ofplantain so much as is sufficient to make them into troches accordingto art culpeper these also stop blood, help the bloody flux, stop themenses, and are a great help to such whose stomachs loath theirvictuals i fancy them not trochisci diaspermaton galen college take of the seeds of smallage, and bishop weed, of eachan ounce, annis and fennel seeds, of each half an ounce, opium, cassialignea, of each two drams, with rain water, make it into trochesaccording to art culpeper these also bind, ease pain, help the pleurisy hæmoptoici pastilli galen college take of white starch, balaustines, earth of samos, juiceof hypocystis, gum, saffron, opium, of each two drams, with juice ofplantain, make them into troches according to art culpeper the operation of this is like the former troches of agarick college take of choice agarick three ounces, sal gem six drams, ginger two drams, with oxymel simplex, so much as is sufficient, makeit into troches according to art oils simple oils by expression oil of sweet almonds college take of sweet almonds not corrupted, as thesis as you will, cast the shells away, and blanch them, beat them in a stone mortar, beat them in a double vessel, and press out the oil without heat culpeper it helps roughness and soreness of the throat and stomach, helps pleurisies, encreases seed, eases coughs and hectic fevers, by injection it helps such whose water scalds them. Ulcers in thebladder, reins, and matrix you may either take half an ounce of it byitself, or mix it with half an ounce of syrup of violets, and so takea spoonful at a time, still shaking them together when you take them:only take notice of this, if you take it inwardly, let it be new drawn, for it will be sour in three or four days oil of bitter almonds college it is made like oil of sweet almonds, but that you need notblanch them, nor have such a care of heat in pressing out the oil culpeper it opens stoppings, helps such as are deaf, being droppedinto their ears, it helps the hardness of the nerves, and takes awayspots in the face it is seldom or never taken inwardly oil of hazel nuts college it is made of the kernels, cleansed, bruised, and beat, andpressed like oil of sweet almonds culpeper you must put them in a vessel viz a glass, or essay suchthing and stop them close that the water come not to them when you putthem into the bath the oil is good for cold afflictions of the nerves, the gout in the joints, &c college so is oil of been, oil of nutmegs, and oil of mace drawn oleum caryinum college is prepared of walnut kernels, in like manner, save onlythat in the making of this essaytimes is required dried, old, and ranknuts oleum chryessaylinum college is prepared in the same manner of apricots, so is alsooils of the kernels of cherry stones, peaches, pine-nuts, fisticnuts, prunes, the seeds of oranges, hemp, bastard saffron, citrons, cucumbers, gourds, citruls, dwarf elder, henbane, lettuce, flax, melons, poppy, parsley, radishes, rape, ricinum, sesani, mustard seed, and grape stones culpeper because most of these oils are out of use, i took not thepains to quote the virtues of them. If any wish to make them, let themlook to the simples, and there they have them. If the simples be not tobe found in this book, there are other plentiful medicines conducing tothe cure of all usual diseases. Which are oil of bays college take of bay-berries, fresh and ripe, so thesis as you please, bruise them sufficiently, then boil them in a sufficient quantity ofwater till the oil swim at top, which separate from the water, and keepfor your use culpeper it helps the cholic, and is a sovereign remedy for anydiseases in any writing of the body coming either of wind or cold college common oil of olives, is pressed out of ripe olives, notout of the stones oil of olives omphacine, is pressed out of unripeolives oil of yolks of eggs college boil the yolks till they be hard, and bruise them withyour hand or with a pestle and mortar. Beat them in an earthen vesselglazed until they begin to froth, stirring them diligently that theyburn not, being hot, put them in a linen bag, and sprinkle them witharomatic wine, and press out the oil according to art culpeper it is profitable in fistulas, and malignant ulcers, itcauses the hair to grow, it clears the skin, and takes away deformitiesthereof, viz tetters, ringworms, morphew, scabs simple oils by infusion and decoction oil of roses omphacine college take of red roses before they be ripe, bruised in a stonemortar, four ounces, oil omphacine one pound, set them in a hot sun, in a glass close stopped, a whole week, shaking them every day, thenboil them gently in a bath, press them out, and put in others, use themin like manner, do so a third time. Then keep the oil upon a pound ofjuice of roses oil of roses complete, is made in the same manner, with sweet and ripe oil, often washed, andred roses fully open, bruised, set in the sun, and boiled gently in adouble vessel, only let the third infusion stand in the sun forty days, then keep the roses and oil together in the same manner is made oil of wormwood, of the tops of commonwormwood thrice repeated, four ounces, and three pounds of ripe oil;only, the last time put in four ounces of the juice of wormwood, whichevaporate away by gentle boiling oil of dill. Of the flowers and leaves of dill four ounces, completeoil, one pound, thrice repeated oil of castoreum. Of one ounce of castoreum oil one pound, wine fourounces, which must be consumed with the heat of a bath oil of chamomel which more than one call holy of complete oil, and fresh chamomel flowers, the little white leaves taken away, cut, bruised, and the vessel covered with a thin linen cloth, set in thesun, pressed out, and three times repeated oil of wall-flowers, as oil of dill oil of quinces. Of six writings of oil omphacine, the meat and juiceof quinces one writing, set them in the sun fifteen days in a glass, andafterwards boil them four hours in a double vessel, press them out, andrenew them three times oil of elecampane. Of ripe oil, and the roots of elecampane bruised, and their juice, of each one writing, and of generous wine half a writing, which is to be evaporated away oil of euphorbium. Of six drams of euphorbium, oil of wall-flowers, and sweet wine, of each five ounces, boiling it in a double vessel tillthe wine be consumed oil of ants. Of winged ants infused in four times their weight ofsweet oil, set in the sun in a glass forty days, and then strain it out oil, or balsam of st john wort simple, is made of the oil of seedsbeaten and pressed, and the flowers being added, and rightly set in thesun oil of jesmine, is made of the flowers of jesmine, put in clear oil, and set in the sun and afterwards pressed out oil of orris, made of the roots of orris florentine one pound, purple orris flowers half a pound. Boil them in a double vessel in asufficient quantity of decoction of orris florentine, and six pounds ofsweet oil, putting fresh roots and flowers again and again.

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The tablet containing 1/64grain of someone to write my assignment iron arsenate contains 1/210 grain of iron. 4 minims of thenuclein solution assuming it to be the “nuclein solution-abbott”would contain but 2/5 of a grain of nuclein-- a substance which even inlarge doses is of questionable therapeutic value the amounts of ironand nuclein contained in doses of this preparation are insignificantin comparison with the amounts present in ordinary foods the onlysubstances present in even small therapeutic doses are strychnin andarsenic the effects of arsenic and strychnin are very differentand there are comparatively few conditions in which they should beprescribed at the same time hence a preparation containing thesetwo in fixed proportions is illogical -- from reports of council onpharmacy and chemistry, 1919, p 92 “anti-pneumococcic oil” and the use of camphor in pneumonia report of the council on pharmacy and chemistrythe council has adopted and authorized publication of the report whichappears below this report declares “anti-pneumococcic oil” a solutionof camphor in oil sold by eimer and amend, new york ineligible fornew and nonofficial remedies because 1 the recommendations for itsuse in pneumonia are not warranted by the evidence, 2 the name isnot descriptive of its composition but is therapeutically suggestive, and 3 the sale of a solution of camphor in oil under a namenondescriptive of its composition is unscientific and a hindrance totherapeutic progress w a puckner, secretary the council having decided to consider anti-pneumococcic oil eimerand amend, new york, the preparation was assigned to the committee ontherapeutics for report the report that follows was made by a memberof this committee:according to the advertising, anti-pneumococcic oil is a “twenty-fiveper cent solution of camphor in a thin oil” which was “originated” byaugust seibert, m d the following directions are given for its use. “10 c c 150 minims to every 100 pounds of body weight, to be injected hypodermically every eight to twelve hours in pneumococcic pneumonia, as soon after the initial chill as possible ”it is claimed that the prescribed dose one hour before generalanesthesia begins, “safeguards against postoperative pneumonia, ” and, that “animals can so be immunized against later and otherwise fatalintravenous pneumococcic infection boehnke, institute for experimentaltherapy, frankfort ” the advice is given. “in pneumococcic meningitis, endocarditis and pleuritis, 3% of salicylic acid should be added to this oil ”in an article by seibert, “camphor and pneumococci” medicalrecord, april 20, 1912, a reprint of which is used to advertiseanti-pneumococcic oil, previous work münchen, med wchnschr , no 36, 1909 is mentioned as the starting point for the use of camphor inpneumonia in this article, the author reports his first case, that ofa young woman who entered st francis’ hospital on the third day afterthe initial chill “with the symptoms of severe toxemia unconscious, temperature 105 5 f , pulse 130, and respiration 40 and involvement ofboth lower lobes ” “large doses of camphor, ” 12 c c of a 20 per cent solution, were injected hypodermically “every twelve hours, resultingin gradual improvement and recovery by the fourth day, without acrisis ” seibert reports success in its use in twenty-one paper, butgives no case histories or protocols he admits, however, that infour out of sixteen paper, following the first twenty-one so reportedcertain “limitations of this treatment were observed, ” and a “suddenrise of temperature in two patients on the second and third days oftreatment, respectively, proved to be due to pneumococcic nephritis, promptly subdued by appropriate doses of urotropin, while the camphorinjections were continued and resulting in speedy recovery ” he furtheradmits that empyema occurs, and states. “this proves that the camphorbrought into the blood cannot prevent the as yet living organisms, constantly entering the blood current from the affected alveoli, fromcolonizing in the renal and pleural tissue ”he reports, among thirty-seven patients treated in this manner, one death, that of a man 68 years old, weighing 200 pounds, with afatty heart heart failure was the real cause of death seibert alsoreports essay very incomplete experimental work. Dr hensel, assistantand pathologist of the german hospital, found that “1/10, 000 writingof camphor added to the usual culture media inhibited the growthof pneumococci, while the controls all thrived”. Dr j c welch, pathologist of the lying-in hospital, found that rabbits infectedwith lethal doses of pneumococcus cultures intravenously were savedby large doses of camphorated oil. Fragmentary protocols are given the assistant pathologist of st francis’ hospital carried on theexperimental work, adding salicylic acid to the camphor no bloodcultures are reported the conclusion reached by dr seibert is thatsalicylic acid up to 3 per cent , added to the camphorated oil, iseffective in preventing pleural infection in the article by dr seibert, there appear most sketchy reports of paper, recovery beingreported without crisis in from three to nine days the referee has made a careful search of the literature, with thefollowing results. Boehnke berl klin wchnschr 50:818, 1913, using white mice, failed to confirm the experiments reported inseibert paper, unless camphorated oil were given before thepneumococci, and even then, he felt that the results were too irregularto be of great significance when given with anti-pneumococcic serum, however, he felt that there was essay benefit to be seen by theadministration of camphor. His protocols, however, are not detailed there is no report of blood cultures, etc another worker, h leo deutsch med wchnschr 39:690, 1913, reported that camphor water given intravenously prolonged the lives ofthirty-eight rabbits inoculated with pneumococci here again there wereno adequate protocols and very little evidence of careful experimentalwork appears in the literature of the past ten years, there appear sketchy clinicalarticles on the value of huge doses of camphor in pneumonia markevitch russk vrach, june 27, 1914.