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Reddish mixture personal essay writing service. same with conc odor of hcl no hcl. h₂so₄ eucalyptol odor alcohol ki no iodin same same as abbott liberated product heating decomposes and apparently does not boils at decompose. Essay 103-105 c.

Quick absorption, insuring prompt action, rapid and complete excretion, affording protection from cumulative toxic after effects, and the choice of rectal and subcutaneous administration ”there is no justification for the claim that diethylbarbituric acid barbital has only one objectionable feature and that a minor matterof “insufficient solubility ” the council has called the attention ofschering and glatz, inc , to the fact that the difference in the timeof absorption between medinal barbital sodium and barbital is, at themost, but one of minutes and that there is no evidence that medinal isexcreted more rapidly than barbital hence the claims that the dangerof toxic side-actions and that cumulative after-effects are avoided inthis product, are wholly unwarranted it is also claimed, and the claim is unsupported by satisfactoryevidence, that medinal is useful in the insomnia of tuberculosis inwhich condition it is said to have a double advantage owing to itsfavorable effects on the night-sweats it is claimed that medinalis used in the withdrawal treatment of morphin addiction with greatsuccess. There is no evidence that medinal has any special usefulnessin this treatment of the morphin habit it is claimed further thatsuccess has been reported with medinal in the treatment of whoopingcough the council knows of no satisfactory evidence to show thatmedinal is of special value in whooping cough. On the contrary, it iscapable of doing a great deal of harm the recommendations that medinalbe used for the control of labor pains and in acute neuralgic painsthat resist other forms of treatment are wholly unwarranted as thevalue of the drug in such conditions is inherently improbable and untilsatisfactory evidence in support of them is forthcoming, must be deemedmisleading -- from the journal a m a , nov 15, 1919 omission of cotarnin salts stypticin and styptol from n n r report of the council on pharmacy and chemistrythe council has authorized publication of the following report w a puckner, secretary salts of the base cotarnin have been used as local and systemichemostatics the hydrochlorid was first introduced as “stypticin, ”and is now in the pharmacopeia as cotarnin hydrochlorid cotarninae hydrochloridum, u s p the phthallic acid salt ofcotarnin-- cotarnin phthallate-- was introduced as “styptol ” bothstypticin and styptol were admitted to new and nonofficial remedies in1918 the council voted to omit stypticin because the former americanagents were no longer offering it for sale styptol was retained and isdescribed in n n r , 1919 as was pointed out in the description n n r , 1918, the evidencefor the usefulness of the cotarnin salts has been contradictory andunsatisfactory. But since the available data against the efficiencywere at least equally unreliable, the council deemed it best to retainthem in n n r pending a thorough investigation of the subject thiswas undertaken by p j hanzlik, at the suggestion of the therapeuticresearch committee of the council a reliable judgment of hemostatic efficiency can be formed only on abasis of strictly controlled conditions, which can best be furnished inthe laboratory hanzlik repeated the principal experiments publishedby previous investigators, and applied a number of new or improvedmethods the results published in the journal of pharmacologyand experimental therapeutics 10:523, 1918. 12:71, 1919 show thefollowing:direct application to wounds -- the widely quoted results of thegynecologist k abel, on the footpad of cats, were found to be quiteunreliable when the experiment is properly controlled, the resultsare either negative or the bleeding may be increased quantitativeexperiments on wounds of the footpad of dogs showed that cotarnininvariably increased the bleeding equally negative or unfavorableresults were obtained with wounds to the comb of roosters, and to theliver and spleen direct action on vessels -- the results of perfusion experiments werevariable, but, in general, showed a vasodilation action instead ofconstriction this holds true also of the uterine vessels the vesselsin the living animal rabbit ear were also unaffected systemic administration -- the bleeding from an irrigated wound wasnot modified directly by intravenous injection of cotarnin salts, butvaried merely with the state of the blood pressure the evidence for the inefficiency of cotarnin salts as hemostaticsseemed so conclusive as to warrant the council in rescinding theacceptance of styptol, and directing the omission of the generalarticle on cotarnin salts and the description of styptol from new andnonofficial remedies -- from the journal a m a , nov 22, 1919 micajah wafers and micajah suppositories report of the council on pharmacy and chemistry“micajah medicated wafers” and “micajah suppositories, ” sold bymicajah & co , warren, pa , are declared inadmissible to “new andnonofficial remedies” because 1 their composition is essentiallysecret rule 1. 2 name of neither of these mixtures is indicativeof its composition rule 8. 3 of exaggerated and unwarrantedtherapeutic claims rule 6, and 4 the therapeutic advice whichaccompanies the trade packages constitutes an indirect advertisement tothe public rule 4 w a puckner, secretary micajah medicated wafers formerly called “micajah medicateduterine wafers” were analyzed in the a m a chemical laboratory in1910 they were found to consist essentially of dried “burnt” alum, boric acid and borax, in approximately the following proportions. Alum, dried 59 86 per cent borax, dried 15 62 per cent boric acid 5 67 per cent water of hydration 18 85 per cent there are a number of drugs that are more or less effective in thetreatment of local lesions of mucous membranes and the skin theyare classed as astringents among these are included alum, boraxand boric acid every physician has used them to say that a waferconsists of alum, borax and boric acid inspires but little awe butthere is essaything much more mysterious and impressive in declaringthat a wafer “consists of an astringent and antiseptic base, in whichare incorporated certain medicaments which both locally and afterabsorption, contribute to the astringent, antiphlogistic, depletive, soothing and healing action of the product ” this gives the impressionthat essay powerful and almost incomprehensible factors are at work yet, after all is said and done, the substances contained in micajahmedicated wafers are just the homely old alum, boric acid and borax in addition to “micajah medicated wafers, ” micajah & co also put out“micajah suppositories for hemorrhoids ” these have been examined inthe a m a chemical laboratory and, like the “medicated wafers” havebeen found to contain alum, boric acid and borax-- and these substancespractically alone-- incorporated in cocoa butter the company claimsthat “to these have been added ammonii ichthyosulphonate, balsam ofperu, ext belladonae ” the a m a chemists report, however, that ifextract of belladonna is present at all it is in amounts too small tobe detected by the method commonly employed in the chemical examinationof alkaloidal drugs the chemists report further that while ammoniumichthyosulphonate and balsam of peru both have a decided odor and aredark in color, the suppositories have but little color and the odor ofthe cocoa butter that forms their base is not covered by these drugs;obviously, therefore, if ammonium ichthyosulphonate and balsam of peruare present at all it is in amounts utterly insufficient to exert anytherapeutic effect it would be hard to find better examples of mischievous proprietarymedicines than these two products of the micajah company “twinsof efficiency, ” they are called in an advertising pamphlet thecomposition is not stated a physician using the “twins” does soabsolutely in the dark to him they are secret preparations he isencouraged to use them in a great variety of conditions in which otherdrugs are much more useful inevitably, physicians using them will belikely to overlook, or pass over, new growths, specific infections anddiseases that require radical remedial measures in addition to misleading and exaggerated claims, there is a referenceto a report from the usual “well-known and reliable bacteriologicallaboratory ” the excerpts published from this report of an unnamedlaboratory are sufficiently vague to incriminate no one from time to time it is worth while to emphasize facts regardingproprietary medicines that while obvious are essaytimes forgotten forthis reason attention is directed to micajah uterine wafers andmicajah suppositories -- from the journal a m a , nov 29, 1919 alkalithia report of the council on pharmacy and chemistryalkalithia was introduced at a time when it was believed that theadministration of lithium salts served to remove uric acid from thesystem the product was considered by the council in 1906, and foundineligible for new and nonofficial remedies no report, however, waspublished at that time because of inquiries received, the council examined the current claimsfor alkalithia, and authorized publication of the report which appearsbelow w a puckner, secretary keasbey and mattison company effervescent alkalithia is sold with thefollowing statement of composition. “each dose or heaping teaspoonful contains 1 grain of caffeine, 10 grains each of bi-carbonates of soda and potash, and 5 grains of carbonate of lithia ”the a m a chemical laboratory reports that alkalithia is aneffervescent mixture which contains alkaline carbonates andbicarbonates together with caffein, free tartaric acid and free citricacid the major portion of the alkali carbonates and bicarbonatesis converted into citrates and tartrates when the preparation isdissolved in water-- as is done before it is taken an excess of alkaliis present, however, as the solution has an alkaline reaction each“heaping teaspoonful” which was found to be about 4 85 gm containsabout 0 044 gm of caffein the manufacturers claim 0 0648 gm perheaping teaspoonful as taken, alkalithia, therefore, representscaffein in a solution of alkali tartrate, citrate and bicarbonatecontaining free carbonic acid if it is assumed that all of thetartrate and citrate in alkalithia is converted into carbonate inthe organism, a “heaping teaspoonful” of alkalithia would representabout 2 9 gm of sodium bicarbonate this assumption is, however, notcorrect, for it is known that tartrates are not completely convertedinto carbonates in the organism according to the label on the bottle, this mixture of caffein andalkali salts is “a common sense remedy for the relief and treatmentof conditions dependent upon perverted metabolism as manifested byneuralgic, rheumatic, cardiac and renal symptoms ” wrapped with a tradepackage is a circular in which is discussed the “uric acid diathesis”as “a cause of rheumatism in its various forms, calculus, gravel andinflammation of the bladder and kidneys, asthma, hay fever, catarrh, quinsy and bronchitis, eczema, hives, itching and burning of the skin, palpitation of the heart and cold hands and feet, dizziness, mentaldepression, melancholia, neuralgia, chorea, hysteria, numbness and agreat variety of purely nervous symptoms ” the arguments for the useof alkalithia as “a safe and scientific treatment for the uric aciddiathesis” found in the circular constitute an indirect appeal to thelaity conflict with rule 4 in the circular matter sent direct to the physicians, keasbey andmattison claim that in rheumatism, alkalithia is prescribed by themedical profession more often than any other remedy the claim is madethat, “in five minutes the urine will be discolorized and analysis willshow it to be loaded with urates ” the manufacturers further assert. “you can change the character of the urinary secretion in a few minutes completely” by alkalithia, and “in nine paper out of ten, when the doctor prescribes ‘alkalithia’ his patient greatly improves, or gets well ”the firm advises that “renal insufficiency” be determined by the oldmethod of multiplying the ounces of urine in twenty-four hours by thelast two numbers of the specific gravity, adding 10, which gives thenumber of grains of solids excreted in the twenty-four hours if thisis low, no matter what the cause, they advise alkalithia, “that idealeliminant ”the council declared alkalithia inadmissible to new and nonofficialremedies because the claims made on the label and the circularaccompanying the trade package lead the public to its detriment todepend on this preparation rule 4. And because the therapeutic claimsare unwarranted rule 6 -- from reports of council on pharmacy andchemistry, 1919, p 65 arhovin omitted from n n r report of the council on pharmacy and chemistryarhovin is a solution of dephenylamine, thymol benzoate and ethylbenzoate, marketed by schering and glatz, inc it was omitted fromnew and nonofficial remedies because the therapeutic claims made forthe preparation were unwarranted and because the firm had refused todiscontinue the distribution of the advertising which contained theobjectionable claims prior to jan 1, 1919 when the report whichappears below explaining the dismissal was submitted to schering andglatz, inc , the firm again promised a revision of its advertising, but refused discontinuance of the objectionable circular before jan 1, 1920 since arhovin is still marketed with unwarranted therapeuticclaims, the council has authorized publication of this report w a puckner, secretary the attention of the firm schering and glatz, inc , was called tomisleading statements in its booklet for arhovin in 1915, and in 1918the firm was informed that unless the misleading statements werewithdrawn before jan 1, 1919, arhovin would be omitted from new andnonofficial remedies the following quotations are taken from the circular in question, andillustrate the character of the claims to which objection was made. “striking also is the antiphlogistic and anesthetic effect of arhovin on the inflamed mucosae, an effect which, as all authorities agree, is far greater than that of all other internal anti-gonorrheaics ” “under its influence vesical and prostatic complications, gonorrheal arthritis, endocarditis, etc , are rarely incurred ”references to the indexes of leading textbooks, including thoseof meyer and gottlieb, cushny, sollman and bastedo, fails to showthat arhovin is so much as mentioned by those authors. Hence, it isobviously false to state, as is done in the first of the quotationsabove, that all authors agree concerning the striking effects ofarhovin thesis of the statements are objectionable by reason of the actionsimplied, rather than stated directly the following are examples. “arhovin in gonorrheal infections of the male genito-urinary organs anterior urethritis this is the class of paper in which the most favorable results from arhovin have been reported ” “posterior urethritis “here also the striking effects from arhovin medication, both in acute and chronic paper, are rapid decrease of discharge, disappearance of gonococci from the secretion, and cessation of subjective difficulties, such as strangury ”while the firm did not agree to withdraw the objectionable advertisingbefore jan 1, 1919, which made necessary the omission of arhovin fromnew and nonofficial remedies, 1919, it did submit a proposed folder inwhich the most objectionable of the claims are still made the following statement, which was in the proposed “folder” and isincluded in an advertising pamphlet sent out during 1919, serves toillustrate those points.

tongaline and lithia tablets, we areinformed, are. “ writingicularly indicated for certain diseases which are caused by deposits of urates in the joints and kidneys, and can be used with much benefit for thesis people who indulge in generous or intemperate habits of living ”tongaline and quinine tablets are also exploited without statementof composition the promoters are probably justified in feeling thatphysicians who prescribe quinin in combination with “tongaline” carelittle about the dosage it is unnecessary to discuss the silly claims made for tongaline andits combinations, although it is worth while to point out that theprescribing of such nostrums by physicians is an imposition, if not afraud, on the public ponca compoundponca compound, also made by the mellier drug company, st louis, is a“female weakness remedy” in tablet form the name suggests that “ponca”is a medicinal substance, and, in fact, at one time, “ext ponca” wasnamed as an ingredient the nature of “ext ponca” was apparently neverexplained it is now replaced in the “formula” by “senecin, ” and theonly information concerning the composition at present given is. “ponca compound tablets contain extract of mitchella repens, senecin, helonin, caulophyllin and viburnin ”this “formula” is practically meaningless, not only because theamount of each ingredient is not stated, but also because “senecin, ”“helonin, ” “caulophyllin” and “viburnin” are in themselves variablemixtures of unknown composition 1313 see report of the council on pharmacy and chemistry on “resinoidsand concentrations, ” j a m a , nov 13, 1909, p 1655 presumably, “senecin, ” “helonin, ” “caulophyllin” and “viburnin” areextractives of essay kind prepared, respectively, from senecio aureus life root, helonias dioica false unicorn, calophyllum thalictroides blue cohosh and viburnum prunifolium or opulus black haw or crampbark these are, one and all, practically inert drugs there is noreason to believe that any or all of them can have any beneficialinfluence in the thesis and varied conditions for which ponca compound isadvertised the following are excerpts from the advertising matter. “ponca compound is a remedy of a very beneficial character for functional, uterine and ovarian troubles, which will respond to internal treatment, especially when digital examination or surgical interference is undesirable ” “ponca compound is also valuable during gestation and after writingurition ” “uterine alterative for leucorrhoea, dysmenorrhoea, amenorrhoea, metritis, endometritis, menorrhagia, metrorrhagia, irregular menstruation, subinvolution, painful pregnancy ”it is recommended that tongaline and ponca compound and all theirpreparations be held in conflict with rule 1, in view of theirsemisecret and indefinite composition. With rule 6, for the grosslyexaggerated therapeutic claims made for them. With rule 8, because oftheir misleading names, and with rule 10, in view of their unscientificcharacter as irrational combinations it is also recommended that thisreport be published -- from the journal a m a , july 17, 1915 alfatone report of the council on pharmacy and chemistrythe council has found alfatone ineligible for new and nonofficialremedies and has authorized publication of the following report w a puckner, secretary alfalfa is good cattle feed but only nostrum exploiters have suggestedits use as a medicine for human beings while it may seem a waste oftime to discuss the medicinal value of alfalfa its recent exploitationby the norwich pharmacal company, norwich, n y , as “a reconstructivetonic and nutrient” in the form of a mixture called “alfatone, ” callsfor comment according to the label on the preparation. “each fluidounce represents. alcohol 15 per cent medicago sativa alfalfa 120 grains taraxacum 2-1/2 grains gentian 1 grain berberine hydrochloride 1/40 grain glycerin and aromatics ” “dose -- one to three fluidrams 4 to 12 c c 4 times daily ”each maximum dose, therefore, should represent 45 grains of alfalfa, 1grain of taraxacum dandelion, 3/8 grain of gentian, 1/100 grain ofberberin hydrochlorid, and 27 minims of alcohol since the bitter drugsare present in such small amounts that the preparation is almost devoidof bitterness, and as the medicinal value of alfalfa is practicallynil, it is evident that whatever action alfatone may have is due to thestimulant effects of the alcohol essay of the claims made for alfatone are. “a reconstructive nutritive tonic indicated in general debility, neurasthenia, convalescence, etc ” “ a galactagogue of merit as well ” “ improves the appetite, aids the processes of digestion and assimilation, facilitates elimination and effects gradual but decided gains in strength, vitality and weight ”it is suggested that. “ in case of idiosyncrasy the addition of tr nux vomica 5 to 10 minims to the dose, unless contraindicated, will secure excellent results ”the norwich pharmacal company naively remarks. “the dearth of medical literature on alfalfa has lead us to present below a few of the findings of the bureau of plant industry of the dewritingment of agriculture as well as those from several state experiment stations ”here are the “findings”. “ digestible nutrients in 100 pounds of alfalfa, protein, 11 0 pounds. Carbohydrates, 39 6 pounds. Ether extract, 1 2 pounds ” “ the high value of alfalfa is due to the amount of protein that it contains. To the large percentage of protein that is digestible and the palatability of alfalfa ” “ table showing pounds of elements removed from the soil by one ton of crop alfalfa wheat potash 49 79 12 52 phosphoric acid 8 27 9 08 lime 43 51 2 95 nitrogen 44 01 22 30” “ the abundance of muscle and bone producing material in alfalfa makes this crop especially good ”thus estimates of the value of a farm crop and cattle fodder are madeto do service as testimonials to its therapeutic merit for humanbeings!. has the “patent medicine” promoter ever dared to insult theintelligence of his patrons by a cruder absurdity?. yet it is not to thenontechnical and unscientific public, but to a profession presumablyscientifically trained in pharmacology and therapeutics that thisconcern presumes to offer its fodder tincture on the basis of testimonyto the agricultural value of the fodder plant alfatone is a worthless alcoholic cordial the audacity of the attemptto promote its sale by a discourse on the merits of a well-known fodderplant is the sole reason for devoting any attention to it it isrecommended that alfatone be held ineligible for new and nonofficialremedies, and that this report be published editorial note -- what a comment on american medicine that a concerncan even contemplate the possibility of making a commercial successof the sale of such a silly nostrum as alfatone!.

It also asked for evidence of the therapeutic value of thepreparations in reply, mark white wrote. “all that i can say regarding the serum is that it is made from the blood of goats with thyroid affection, and it has been found that the serum from these goats has antibodies which control, or has curative effect upon thyroid affections when injected into thyroid glands of either humans or animals as to the iodinised oil, it is only an adjunct or side treatment which is not always used or indicated, and will only be furnished to the physician for use in case in his judgment his patient needs it we shall also advise the use of quinin when indicated ”the council was referred for further information to a paper by rachelwatkins, m d , published in the illinois medical journal it is tobe noted, incidentally, that the letterheads used by white in hiscorrespondence bore in one corner the notation “rachel watkins, m d , practice limited to goiter and other disorders of the thyroid glands, ”and in the other, “mark white, goiter research ”the information regarding the composition of this goiter treatment, asfurnished in dr watkins’ paper, was to this effect. “the medical treatment consists of the administration of a blood serum derived from a thyrodized goat formula. Iodine 0 16 grams according to a correction by mark white, this should read 0 26 gm , oil 0 25 c c , serum q s 1 c c ”this description of the treatment differs from that furnished to thecouncil by mark white in that here the iodin and oil appear to becombined with the serum dr watkins’ “formula” implies that the iodinis a routine medication, thus contradicting white statement, which, in turn, is at variance with the statements made in submitting thetreatment illustration. Photographic reproductions greatly reduced of essay ofthe letterheads used by the mark white concern during the past fiveyears the council does not accept any biologic product until its sale ininterstate commerce has been authorized by the secretary of thetreasury in accordance with the federal law regulating the sale ofviruses, serums, toxins and analogous products the sale of the markwhite goiter serum has not been so authorized. Consequently even if thepreparation complied with other rules of the council it could not beaccepted in addition, however, this treatment conflicts with other councilrules the statements regarding its composition are indefiniteand contradictory rule 1.

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Heelsraised. Knees half bent the text says that the knot was nearly underthe right ear, but the illustration shows a different position seefig 22, p 743 23 allison. Lancet, 1869, i , p 636 - three paper of suicide byhanging, in which there was no mark. 1st woman, hung herself with apiece of sheep-net band. Cut down before death 2d man, hung withplough-string. Cut down in about six minutes 3d a heavy man 24 tardieu. Op cit , pp 93-105 - woman, died of coma and asphyxiafrom suicidal hanging, according to report of drs costan and facieu tardieu approved their report it was at first thought a case ofhomicide with subsequent hanging, more especially because of the kindof knot used, nœud d’artificier but tardieu showed that it was alsoa nœud de batalier her feet touched a chair, and her knees werebent there was a neckcloth in front of her mouth, but it did not seemto have interfered with respiration 25 ibid , pp 67-72 - the famous case of marc-antoine calas, whocommitted suicide by hanging see voltaire, “traité sur le tolérance, ”etc , in nouv philos histor , 1772, xxxii , p 30 he hung himselfto a door no sign of violence the city hangman said it was impossiblefor a man to commit suicide in that way the father was accused andconvicted of homicide tardieu shows that the act was a suicide 26 ibid , p 72 - another famous case a woman, age 30, hung herselfto the key of her bedroom door her husband cut her down he wasaccused and convicted of the crime and condemned to prison, where hedied tardieu showed that the case was one of suicide 27 hofmann. Wien med presse, 1880, xxi , p 201 - man, age 68, suicide by hanging there was profuse hemorrhage from both ears 28 ibid. 1878, xix , pp 489-493 - woman, found dead sitting inbed she first tried to poison herself with arsenic, then hung herself 29 ibid - man, tried to poison himself with phosphorus and sulphuricacid, then hung himself there was a transverse rupture of thesterno-cleido mastoid muscle and suffusion in its sheath 30 maschka. Wien med woch , 1880, xxx , pp 714, 747, 1075 - man, age 63 it was at first a question of suicide by hanging or homicide bystrangling he concluded that it was the former 31 ibid - also man, age 58 similar case same opinion 32 ibid 1883, xxxiii , pp 1118-1120 - woman age 23 questionwhether she committed suicide by hanging or was strangled and thenhung opinion, that it was a case of suicide 33 hofmann. Allg wien med zeit , 1870, xv , pp 192-214 - man, age 60 suicide by hanging or homicide.