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This writingicular pieceof press agent work dealt with “the new du pont ether ” to quote oneparagraph from the “news item”. The new anesthetic, which is a highly refined di-ethyl ether, modified by the addition of gases, has the following characteristics. 1 the property of inducing and maintaining anesthesia with practical freedom from postoperative nausea, and 2 the property of inducing and maintaining analgesia conscious insensibility to pain as distinguished from anesthesia insensibility to pain plus narcosis the du pont ether and the claims made for it are seemingly based on thework of one man, “james h cotton, m a , m d , toronto, canada, ” whopublished an article on “cotton process ether and ether analgesia, ”in the american journal of surgery for april, 1919 however, cottondid not give the composition of the “new” ether nor, so far as weare aware, has his work been corroborated in view of the inquiriesreceived, the secretary of the council on pharmacy and chemistry askedthe du pont chemical works for the composition of the new ether fromthe firm reply we quote one paragraph. “ the procedures of manufacture, and the exact composition of our ether, we regard as confidential information which we are entitled to retain unless a condition were to arise in which we were unable alone to satisfy the demand for this type of ether ”it has been recognized-- and incorporated in the “principles of medicalethics”-- that the use of a therapeutic agent of unknown compositionis unscientific and contrary to the best interests of the medicalprofession and the public. But it is thesis times more serious for aphysician to employ a secret or semisecret substance as an anesthetic a physician using such a semisecret substance would have little defenseif the patient should die -- query in the journal a m a , feb 21, 1920 a note from the manufacturersin the query and minor notes dewritingment of the journal of february21, essay inquiries from physicians relative to “cotton process ether”were answered in referring to the composition of this product it wasstated that the secretary of the council on pharmacy and chemistry hadasked the manufacturers, the du pont chemical works, for information onthis point and one paragraph from the firm reply was quoted anotherparagraph from the same letter was omitted.

But therefore too much must not be taken, becauseit makes the blood thin and wheyish, and turns it into choler, andtherefore choleric persons must abstain from it it is a safe medicinefor the biting of a mad dog, being bruised with salt and laid thereon the powder of it being dried and taken after meat, helps digestion, andthose that are splenetic taken with wine, it helps women in their soretravail in child-bearing it is good against the gravel and stone inthe kidneys, and the stranguary being smelled unto, it is comfortablefor the head and memory the decoction hereof gargled in the mouth, cures the gums and mouth that are sore, and mends an ill-savouredbreath. As also the rue and coriander, causes the palate of the mouthto turn to its place, the decoction being gargled and held in themouth the virtues of the wild or horse mint, such as grow in ditches whosedescription i purposely omitted, in regard they are well known areserviceable to dissolve wind in the stomach, to help the cholic, andthose that are short-winded, and are an especial remedy for thosethat have veneral dreams and pollutions in the night, being outwardlyapplied the juice dropped into the ears eases the pains of them, and destroys the worms that breed therein they are good against thevenemous biting of serpents the juice laid on warm, helps the kingevil, or kernels in the throat the decoction or distilled water helpsa stinking breath, proceeding from corruption of the teeth, and snuffedup the nose, purges the head pliny saith, that eating of the leaveshath been found by experience to cure the leprosy, applying essay ofthem to the face, and to help the scurf or dandriff of the head usedwith vinegar they are extremely bad for wounded people. And they say awounded man that eats mint, his wound will never be cured, and that isa long day misselto descript this rises up from the branch or arm of the tree whereonit grows, with a woody stem, putting itself into sundry branches, and they again divided into thesis other smaller twigs, interlacingthemselves one within another, very much covered with a greyish greenbark, having two leaves set at every joint, and at the end likewise, which are essaywhat long and narrow, small at the bottom, but broadertowards the end at the knots or joints of the boughs and branches growsmall yellow flowers, which run into small, round, white, transparentberries, three or four together, full of a glutinous moisture, with ablackish seed in each of them, which was never yet known to spring, being put into the ground, or any where else to grow place it grows very rarely on oaks with us. But upon sundry othersas well timber as fruit trees, plentifully in woody groves, and thelike, through all this land time it flowers in the spring-time, but the berries are not ripeuntil october, and abides on the branches all the winter, unless theblackbirds, and other birds, do devour them government and virtues this is under the dominion of the sun, ido not question. And can also take for granted, that which grows uponoaks, writingicipates essaything of the nature of jupiter, because an oakis one of his trees. As also that which grows upon pear trees, andapple trees, writingicipates essaything of his nature, because he rulesthe tree it grows upon, having no root of its own but why that shouldhave most virtues that grows upon oaks i know not, unless because itis rarest and hardest to come by. And our college opinion is in thiscontrary to scripture, which saith, god tender mercies are overall his works. And so it is, let the college of physicians walk ascontrary to him as they please, and that is as contrary as the eastto the west clusius affirms that which grows upon pear trees to beas prevalent, and gives order, that it should not touch the groundafter it is gathered. And also saith, that, being hung about theneck, it remedies witchcraft both the leaves and berries of misseltodo heat and dry, and are of subtle writings. The birdlime doth molifyhard knots, tumours, and imposthumes. Ripens and discusses them, anddraws forth thick as well as thin humours from the remote writings ofthe body, digesting and separating them and being mixed with equalwritings of rozin and wax, doth molify the hardness of the spleen, andhelps old ulcers and sores being mixed with sandaric and orpiment, it helps to draw off foul nails. And if quick-lime and wine lees beadded thereunto, it works the stronger the misselto itself of the oak as the best made into powder, and given in drink to those that havethe falling sickness, does assuredly heal them, as matthiolus saith:but it is fit to use it for forty days together essay have so highlyesteemed it for the virtues thereof, that they have called it lignumsanctiæ crucis, wood of the holy cross, believing it helps the fallingsickness, apoplexy and palsy very speedily, not only to be inwardlytaken, but to be hung at their neck tragus saith, that the fresh woodof any misselto bruised, and the juice drawn forth and dropped in theears that have imposthumes in them, doth help and ease them within afew days moneywort, or herb twopence descript the common moneywort sends forth from a small threadyroot divers long, weak, and slender branches, lying and running uponthe ground two or three feet long or more, set with leaves two at ajoint one against another at equal distances, which are almost round, but pointed at the ends, smooth, and of a good green colour at thejoints with the leaves from the middle forward come forth at everypoint essaytimes one yellow flower, and essaytimes two, standing each ona small foot-stalk, and made of five leaves, narrow-pointed at the end, with essay yellow threads in the middle, which being past, there standin their places small round heads of seed place it grows plentifully in almost all places of this land, commonly in moist grounds by hedge-sides, and in the middle of grassyfields time they flower in june and july, and their seed is ripe quicklyafter government and virtues venus owns it moneywort is singularlygood to stay all fluxes in man or woman, whether they be lasks, bloody-fluxes, bleeding inwardly or outwardly, or the weakness of thestomach that is given to casting it is very good also for the ulcersor excoriations of the lungs, or other inward writings it is exceedinglygood for all wounds, either fresh or green, to heal them speedily, and for all old ulcers that are of spreading natures for all whichpurposes the juice of the herb, or the powder drank in water whereinhot steel hath been often quenched. Or the decoction of the green herbin wine or water drank, or used to the outward place, to wash or bathethem, or to have tents dipped therein and put into them, are effectual moonwort descript it rises up usually but with one dark green, thick andflat leaf, standing upon a short foot-stalk not above two fingersbreadth.

And the same made into a lotion, and essay honey andalum, cures all sores in the mouth and gums, be they ever so foul, orof long continuance. And works no less powerfully and effectually forsuch ulcers and sores as happen in the secret writings of men and women being also taken inwardly, or outwardly applied, it helps those thathave broken any bone, or have any member out of joint an ointment madewith the leaves of bugle, scabions and sanicle, bruised and boiled inhog grease, until the herbs be dry, and then strained forth into apot for such occasions as shall require. It is so singularly good forall sorts of hurts in the body, that none that know its usefulness willbe without it the truth is, i have known this herb cure essay diseases of saturn, ofwhich i thought good to quote one thesis times such as give themselvesmuch to drinking are troubled with strange fancies, strange sightsin the night time, and essay with voices, as also with the diseaseephialtes, or the mare i take the reason of this to be accordingto fernelius a melancholy vapour made thin by excessive drinkingstrong liquor, and, so flies up and disturbs the fancy, and breedsimaginations like itself, viz fearful and troubleessay those i haveknown cured by taking only two spoonfuls, of the syrup of this herbafter supper two hours, when you go to bed but whether this does itby sympathy, or antipathy, is essay doubt in astrology i know thereis great antipathy between saturn and venus in matter of procreation;yea, such a one, that the barrenness of saturn can be removed by nonebut venus!. nor the lust of venus be repelled by none but saturn. Buti am not of opinion this is done this way, and my reason is, becausethese vapours though in quality melancholy, yet by their flying upward, seem to be essaything aerial. Therefore i rather think it is done byantipathy. Saturn being exalted in libra, in the house of venus burnet it is called sanguisorbia, pimpinella, bipulo, solbegrella, &c the common garden burnet is so well known, that it needs nodescription - there is another sort which is wild, the descriptionwhereof take as follows.

“kora-konia is indicated in the treatment of acne, dermatitis, eczema pay to do my essay and eczematous conditions of the utmost severity, eruptive fevers, ”what purports to be a physician testimonial reads. “i used kora-konia in a new born case of inherited syphilis and the eruption soon cleared up ”germicidal powers are claimed for kora konia in a medical journaladvertisement in view of the various claims made and the fact that itis advertised to the medical profession, the chemical laboratory of theamerican medical association was asked to analyze kora-konia this wasdone and the chemists reported as follows:laboratory reportkora-konia is a white powder, slightly greasy to the touch qualitativetests showed the presence of boric acid, zinc, magnesium, a solid fattyacid and material insoluble in hydrochloric acid containing magnesiumand aluminum starch was not found quantitative determinations gavethe following results. Acid-insoluble material talc 48 3 per cent magnesium mg soluble in dilute acid 1 2 per cent zinc zn 4 5 per cent stearic acid impure 39 2 per cent boric acid 3 0 per cent carbon dioxide co₂   1 5 per cent from this analysis it is concluded that kora-konia has essentially thefollowing composition. Zinc stearate u s p 44 per cent talc 48 per cent magnesium carbonate u s p 5 0 per cent boric acid 3 0 per cent essentially this dusting powder consists of the well-known substancestalc and zinc stearate in about equal proportions to which smallquantities of magnesium carbonate and boric acid have been added inasmuch as the claim is made, by inference at least, that kora-koniarepresents original investigation carried out “with the cooperation ofthe medical profession” it should be stated that the preparation ofcommercial zinc stearate was described and recommended as a dusting andtoilet powder nearly twenty-five years ago 9696 proc am pharm a 40:488, 1892 there is nothing new or original in any one of these substances or inthe combination the extravagant and unwarranted claims made for thissimple dusting powder are undoubtedly leading the public as well asessay thoughtless physicians, to place undeserved confidence in it in view of the small amount of boric acid present in the powder, itsantiseptic powers must be slight and its germicidal powers almost nil the council declared kora-konia ineligible for new and nonofficialremedies and authorized publication of this report -- from the journala m a , sept 30, 1916 the therapeutic value of the glycerophosphates report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary glycerophosphates are the salts of glycerophosphoric acid, h₂c₃h₅ oh₂po₄ this acid is produced by the interaction of glycerinand phosphoric acid in general, only sodium glycerophosphate, na₂c₃h₅ oh₂po₄ 5-1/2h₂o, and calcium glycerophosphate, cac₃h₅ oh₂po₄ h₂o, are used in medicine, though theglycerophosphates of lithium, potassium, manganese, magnesium, iron, quinin and strychnin are claimed as constituents of proprietarypreparations at a time when certain disorders were assumed to be dueto a deficiency of phosphorus in the nerve structure in the body, glycerophosphates were introduced as “nerve foods” and “tonics” on thetheory that they would be assimilated more readily than hypophosphitesor ordinary phosphates what led to this assumption was the fact thatthe lecithins, which form a writing of the nerve structure, were known tocontain the glycerophosphate radical in the molecule the belief thatinorganic phosphates cannot supply the body need of phosphorus isimplied or expressed in most of the “literature” devoted to proprietaryphosphorus preparations thus, schering and glatz quote g meillière as saying that “theorganism is incapable of assimilating inorganic forms of phosphorus ”again, when exploiters of glycerophosphates admit that the body cansynthesize its phosphorus compounds from inorganic phosphates, theyattempt to counterbalance the admission by contending that the useof organic compounds “spares” the system the necessity of makingsuch synthesis this assumption rests on the theory that the organicphosphorus compounds are absorbed and stored as such this theory is contradicted by evidence which has been presented97that the organic phosphorus compounds are split up into inorganicphosphates before absorption 97 mccollum and hart, grosser and husler, plimmer, and bayliss andplimmer, quoted by marshall note 2 the council requested e k marshall, jr , to review the evidence forand against the therapeutic value of organic phosphorus compounds marshall study98 brings out the following points:98 marshall, e k. The therapeutic value of organic phosphoruscompounds, j a m a , feb 13, 1915, p 573 1 in various tissues of the animal body, enzymes have been found whichhydrolyze complex organic phosphorus compounds so as to liberate thephosphorus in the form of inorganic phosphates 2 metabolism studies of the phosphorus balance with diets containinginorganic phosphorus compounds, as compared with diets containingorganically bound phosphorus, are essaywhat conflicting in theirresults the balance of evidence, however, is in favor of the view thatthere is no difference between organically combined phosphorus andinorganic salts with respect to the phosphorus balance 3 experiments indicate that the organism thrives on and supplies itsphosphorus needs quite as well from inorganic phosphorus compounds asfrom organically bound phosphorus marshall concludes:“we see that the evidence is very convincing of the view that theanimal organism can synthesize its complex organic phosphorusconstituents from inorganic phosphates, and that organic phosphorus isof no more value as a food than inorganic ”in view of this report, the council deemed it advisable to take up theconsideration of certain glycerophosphate preparations on the market as the therapeutic claims are all similar, it is not necessary to quotethem extensively tonols schering glycerophosphatestonols schering and glatz, new york comprise iron, lime, lithium, magnesium, manganese, potassium, quinin, sodium and strychnin “tonols”or glycerophosphates. Also duotonol tablets, said to contain equalwritings of calcium and sodium glycerophosphates. Triotonol tablets, each said to contain “sodium tonol 2-1/2 grains, lime-tonol 2-1/2grains, strychnine-tonol 1/60 grain”.

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We are indebted to dr j h moorehead for assistance in writing of thesurgical work -- from the journal a m a , jan 15, 1916 articles refused recognition report of the council on pharmacy and chemistrybelow appear abstracts of the council action on articles refusedrecognition which were not deemed of sufficient importance to requirelengthy reports. Radio-remthe radium therapy company, schieffelin & co , selling agents, submitted to the council radium emanation generators called “radio-remoutfits, ” designed to generate respectively 200, 1, 000, 2, 000, 5, 000and 10, 000 mache units per twenty-four hours those who are well informed on the subject of radium therapy are of theopinion that the administration of small amounts of radium emanationsuch as generated by certain outfits is without therapeutic value ithas been stated that at the radium institute of london the minimumpreliminary dose is 185 microcuries 500, 000 mache units, and as thesisas 555 microcuries 1, 500, 000 mache units are employed in consideration of these facts the council voted not to accept anyradium emanation generator which produces less than 2 microcuriesof emanation during twenty-four hours accordingly, while acceptingradio-rem outfit no 5, claimed to produce 10, 000 mache units 3 7microcuries and radio-rem outfit no 4, claimed to produce 5, 000 macheunits 1 8 microcuries, the council voted not to accept radio-remoutfit no 3, claimed to produce 2, 000 mache units 0 74 microcurie, radio-rem outfit no 2, claimed to produce 1, 000 mache units 0 37microcurie, and radio-rem outfit c, claimed to produce 200 mache units 0 07 microcurie this report having been submitted to schieffelin & co and their replyconsidered, the council authorized publication of the report see alsoreports of council on pharmacy and chemistry, 1916, p 631 olio-phlogosisolio-phlogosis, a liquid preparation to be applied externally by meansof a cotton pad, is advertised by the mystic chemical company, kansascity, mo , thus. “doctor. Don’t fail to use olio-phlogosis liberally for pneumonia, bronchitis and pleurisy it works quickly olio-phlogosis is as far ahead of all medicated kaolin plasters as these plasters were ahead of the old-time moist and soggy poultices ”a pamphlet advises the use of olio-phlogosis in “ all paper of inflammation and congestion, such as pneumonia, bronchitis, pleurisy, croup, boils, carbuncles, rheumatism, swollen glands, peritonitis, ovaritis, as a surgical dressing, mamitis mastitis ?. vaginitis and metritis on cotton tampon to deplete these writings, septic wounds, old ulcers, chilblain, eczema, neuralgia, inflammation of the eyes and ears, alveolar inflammation, burns, scalds, etc ”according to the information sent to the council by the mystic chemicalcompany, olio-phlogosis has the following composition per gallon.