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Against the veil of mystery that makes these abuses possible the individual layman cannot protect himself against these dangers, and has a right to expect that the government will prohibit theindiscriminate sale of any medicine that may be harmful to him he hasa right to expect, when the government permits the sale of a patentmedicine, that the medicine will do him no harm. Just as he has a rightto expect that any physician whom the government permits to practice, should be competent these are essay of the reasons why physicians oppose patent medicinesas they are now exploited. And for these reasons, physicians shouldtake an absolutely uncompromising attitude, and use every opportunityto educate the public the patent medicine interests naturally tryto obscure the issue by the art in which they are so skilful, theyaim to suggest to the public that physicians are opposed to patentmedicines, in order to drive patients to their offices they “forget”to mention that physicians have never conducted a “campaign” againstreally efficient preventive public-health measures, no matter how thesisprospective patients were involved no physician has ever refused togive diphtheria antitoxin because this would diminish the number of hisvisits a short memory is a very convenient asset for self-interestedpersons it is not so convenient for the public-- but it is all toofrequent physicians must, therefore, make it plain that their stand isnot against patent medicines, but for the protection of the health ofthe public -- from the journal a m a , march 4, 1916 drug therapy. The fallibility of textbooksuntil very recently, we were compelled to acknowledge that little, if any, progress was being made in internal medicine so far as drugtherapy was concerned everybody knows of the progress made in otherbranches-- in bacteriology, in pathology, in biologic chemistry, in surgery, in etiology and in application of technical methodsto diagnosis recently, however, pharmacologic research and theapplication of scientific methods in the study of the physiologicaction of drugs are resulting in definite, positive progress animportant lesson, incidentally learned through this scientificinvestigation, is the fallibility of the drug therapy described intextbooks the explanation is, of course, that thesis of these textbooksare mere compilations containing false statements, unproved theories, and unverified clinical evidence representing the guesswork of ancientuncritical observers thesis drugs have been, and still are, vaunted intextbooks as valuable in a variety of conditions, whereas scientificinvestigation and controlled clinical observation have proved them tobe totally worthless. Others are proving to be of value in an extremelylimited number of conditions the sooner writers of textbooks realizethis fact and enter into the spirit of the new era, the better forthe public and for scientific medicine -- editorial from the journala m a , may 27, 1916 thomas webster edgar tired rabbits for diabetes. Ring-tailed monkeys for sex stimulationduring the last two or three years the journal has received inquiriesregarding one thomas webster edgar, m d , of new york city, first, relative to his alleged treatment for diabetes and more recently abouthis “monkey gland” treatment for sex stimulation here is one from aphysician in washington. “have you any knowledge of the efficacy of a serum made from the pancreas of rabbits for the relief or cure of diabetes?. it is made by dr t w edgar of 766 west end ave , new york city ”and this from a layman in pennsylvania.

It is apt to be sharp, severe, darting and neuralgicin character this may last at intervals for essay days, a dull acheoccurring at first between the intermissions it disappears of itselfin time without lasting effects hyperæsthesia may exist at first should this continue, or ifanæsthesia not due to secondary traumatic conditions should appearlater, we should be inclined to place these symptoms in the third class of other symptoms occurring in accidents from currents of highpotential, those which seem to be due to the direct action of theelectricity are not serious buzzing in the ears and a metallic tastein the mouth often occur at the very beginning before the consciousnessis involved nausea and vomiting frequently occur later there isoften considerable dizziness and vertigo patients essaytimes complainof sensations as of an electric shock running through the body whichoccur without cause essay hours or even days after the real shock essayof these sensations are certainly to be reckoned under the mental orpsychical symptoms susceptibility to the effects of electricity, oflightning, and of thunder-storms, though i don't wanna write my paper undoubtedly in thesis paperpsychical, has probably in essay paper an actual foundation this iscertainly the case in lightning stroke on the other hand, in the largemajority of paper of electric accidents no such result follows, and inthesis we are expressly told that such a result was looked for but notfound the temperature, as affected by the electricity alone and not assecondary result of injuries, is not always easy to determine it seemsto be in most paper lowered at first, being in that of moyer 97 5° andin that of robert 97° later it may rise to a certain extent, usuallyto not more than 101°, but here again the influence of traumata isdifficult to separate the pulse may be full and soft or weak and compressible it isfrequently very feeble, essaytimes almost imperceptible, and oftenrapid it is apt to remain rapid and essaywhat soft for days in severepaper the respiration is at first rapid in severe paper unless the shock beso great as to cause its cessation this rapidity remains for a varyingperiod and then disappears as a typical case of the results of shock from an electric wire, wewill mention the one reported by dr f w jackson the patient, aman twenty-two years old, came in contact with a live electric-lightwire, touching it with his hands he was thrown a distance of aboutten feet and then back again, “swinging back and forth two or threetimes ” his hands were in contact with the wire about three minutes, when the current broke and he fell to the ground unconscious was seentwo hours later by physician temperature 100°. Pulse 100, strong andbounding. Pupils dilated. Headache. Nervous and irritable. Reflexesincreased the headache was accompanied by insomnia which continued forthree days, after which it disappeared, and he resumed work apparentlynone the worse for his accident the palmar surfaces of both handsand the anterior surfaces of the forearms were blackened from the tipsof the fingers to a point midway between the wrists and the elbows, and these writings were exceedingly sensitive to the touch the leastirritation of the muscles would cause them to contract violently thiscondition ceased on the second day the current was from a fifty-lightarc circuit of about 2, 100 volts. 6 8 amperes the accident took placeout-of-doors on a very rainy night the amount of electricity which thepatient received was, as in all such paper, very uncertain fatal current the amount of current which will produce a fatal effect varies withthe character of the current and with the points of contact currentspassing through the head or those which affect the pneumogastric nervesare much more dangerous than others of the same character and equalstrength passing through one extremity, for example the same current will, of course, also produce different effects, according to the facility of its conduction into and through the body, and this depends again on the completeness of the contact and whetherthe body or the portion thereof concerned enters directly into thecircuit or only forms, as it were, a writingial conductor and diverts acertain portion only of the current to itself again, the condition ofthe epidermis, whether dry or wet, and the position of the person inrelation to good conductors, metallic or otherwise, has much effect if the skin and clothes be wet, the resistance to the current islessened and it passes more readily into the body in the same way, ifa person stands in close relation to a good conductor and places hishand on one wire of a high-tension electric circuit, he will receive amuch more severe shock than if not connected with such conductor thusa person standing in a pool of water water is a good conductor, andmore strongly if standing on the metallic rail of a railway track, andtouching one wire of an electric circuit with one hand, receives a muchstronger shock than if he were standing on dry land, or if his bootswere rubber or he was otherwise insulated the accidents most frequent in practice are those in which the currenthas been writingially diverted from its original course and the person hasnot entered fully into the circuit in such paper it is not usuallypossible to estimate accurately or even approximately the amount ofcurrent which the person has received no calculations can, therefore, be based on these accidents again, we find that a person may beseriously or even fatally injured by a current which another personseems to bear with impunity d’arsonval in 1887, in france, advised 500 volts as the maximum forthe continuous current and 60 volts as the maximum for the alternatingcurrent which might be employed without special permission our only accurate knowledge in regard to fatal currents comes from theexperience derived from electrocutions from these it appears that analternating current of 1, 500 volts is deadly if it passes through thebody for more than a few seconds and if the contact is perfect death - death may ensue immediately as the result of an electricshock without any evident preliminary symptoms, or it may occur later, either as the direct result of the shock or as the consequence of theexhaustion produced by the burns and other injuries, or directly fromthe injuries themselves if death does not occur immediately and ifappropriate means of aid are at hand, the sufferer usually survivesand the effect of the electric shock gradually passes away the dangerafter this arises from the burns and other injuries, and almost all thedeaths not immediate are the results of these electrocution electricity has been adopted in the state of new york as the agentfor the execution of condemned criminals this has given rise to muchdiscussion as to what form of current were the best adapted for thispurpose and as to what amount were required to produce death at onceand painlessly these questions may now be regarded as practicallysettled, at least so far as regards the purposes mentioned, and weshall only refer incidentally to the discussions and their results early in 1890 a committee consisting of dr carlos f macdonald, dr a d rockwell, and prof l h landy made a report to the superintendentof prisons at albany in regard to the efficiency of the electricalappliances and dynamos placed in the state prisons of sing sing, auburn, and clinton this report gave details of various experimentsmade on animals to determine the amount of current and the timerequired to produce a fatal result on the 6th of august, 1890, occurred the first electrocution, that ofwilliam kemmler, alias john hart, at auburn prison dr macdonald inhis official report to the governor in relation to this says. “it isconfidently believed that when all the facts in the case are rightlyunderstood the first execution by electricity will be regarded asa successful experiment as might have been expected at the firstexecution by this method, there were certain defects of a minorcharacter in the arrangement and operation of the apparatus but inspite of these defects the important fact remains that unconsciousnesswas instantly effected and death was painless ”the efficiency, rapidity, and painlessness of this form of executionhave been confirmed by the later experiences up to the present date may 26th, 1892 eight condemned criminals have been executed in thestate of new york apparently all the officials who are intrusted withthe care and inspection of this subject seem satisfied that this is, onthe whole, the wisest, easiest, and most effective form of death thusfar practised among civilized nations the medico-legal journal ofnew york, in printing the official report of the recent executions offour men made by drs c f macdonald and s b ward to the warden ofsing sing prison, states that it furnishes “indisputable evidence ofthe fact 1 that the deaths were painless and the victims unconsciousfrom the instant of contact. 2 that they were certain and unattendedwith any of the revolting scenes so frequently witnessed at thescaffold. 3 that the method is humane so far as inflicting physicalpain or suffering, and from all sides considered infinitely preferableto the death by hanging. And that so long as capital punishment formurder exists in new york, we need not desire to change the method ofpunishment ” these claims would seem to be thus far substantiated the value of this method of execution is now beyond doubt whenproperly performed it is rapid, painless, and not repulsive thecriminal has probably no physical sensation of pain or discomfort dueto the mode of death from the moment the first shock occurs since therapidity of the transmission of the electric current through the bodyis in these paper much greater than the rapidity of the transmissionof sensation, it seems just to conclude that no sensation from theelectricity reaches the consciousness the only distress sufferedby the criminal is the unavoidable mental suffering natural to hisposition the mechanical means employed in electrocution are practically thesame at sing sing, clinton, and auburn prisons a special room isprovided for the purpose, which should be, if possible, in thebasement with a concrete floor.

“none” indicates that there was no local reaction, and“undetermined, ” that the patient has failed to return after the lastinjection in table 3 all the details of the investigation are recorded under“local reaction, ” the letters represent the type of reaction after eachinjection, in the order in which they were given. When two solutionswere used in the same case, the letters represent the reactionsfollowing the solution opposite which they stand in the fifth columnthe plus and minus symbols indicate the wassermann reaction. Plusindicates a completely positive, and minus a completely negativereaction when there is only one sign, it refers to the reaction at theend of treatment. When there are two, to the reaction before and after the seventh column shows the clinical result at the end of treatment;when no note is made, it means that there was no change noted in theeighth column are noted any objective results observed at the time ofexaminations of the patients the injections were made and the result charted by dr e l zimmermann, of my staff, under my directions andsupervision -- abstracted in the journal a m a , feb 24, 1917 table 3 -- details of investigation by dr keidel | | | | total |dura- |effect | | | case|no |prepar-| local | amount | tion | on | type of | result | general | | ation |reaction |solution| of |wasser-| case | | remarks | | | | given, |treat-| mann | | | | | | | c c | ment | | | | -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- 1 | 3 | 2 | ooo | 3 | 6 da | |latent | | 2 | 5 | 2 | mosms | 5 6 | 9 da | |gummas |marked | 3 | 7 | 1 | mmm. | 9 5 | 3 mo |- to |latent | improve- | | | | others u| | | | | ment | | 3 | 2 | uuu | | | | | | 4 | 1 | 2 | u | 0 75 | | |latent | | 5 | 4 | 1 | sssm | 4 4 | 9 da | - |gummas | |after 4th | | | | | | | | | injection, | | | | | | | | | developed | | | | | | | | | diarrhea. | | | | | | | | | melena 6 | 9 | 1 |ooumsosmu| 9 1 | 1 mo | - |latent | | 7 | 2 | 3 | mm | 3 8 | 2 da | |latent | |well | | | | | | | | | tolerated 8 | 7 | 2 | oooomou | 9 6 |17 da | to |primary |primary | | | | | | | | | healed | 9 | 4 | 1 | smmu | 5 5 | 9 da | |gumma |improved | 10 | 3 | 3 | mss | 3 | 6 da | |palmar |markedly | | | | | | | | syphilis;| improved | | | | | | | | tertiary | | 11 | 7 | 3 | msmmmmm | 10 6 |13 da | to |latent | | 12 | 3 | 2 | mmo | 5 4 |14 da | |secondary |rash |developed | 2 | 1 | sm | | | | papular| disap- | toxic ery- | | | | | | | | pearing | thema on | | | | | | | | | thighs | | | | | | | | | cleared up | | | | | | | | | on stopping | | | | | | | | | hgcl₂ and | | | | | | | | | under local | | | | | | | | | treatment 13 |10 | 3 | mmmmmmmm| 12 6 |20 da | to |secondary |rash |small | | | mmu | | | | lichen | not | induration | | | | | | | syph | improved | following | | | | | | | | | injection | | | | | | | | | of 1 2 c c 14 | 6 | 2 | oomsmm | 7 2 |17 da | to |old | |responded to | 2 | 1 | sm | | | | cerebro- | | doses of | | | | | | | spinal | | 1 c c with | | | | | | | syphilis | | salivation. | | | | | | | | | fever after | | | | | | | | | injection | | | | | | | | | of 1 2 c c 15 | 4 | 1 | soms | 4 2 | 7 da | to |secondary |no | | | | | | | | condyl- | improve- | | | | | | | | omas | ment | 16 | 9 | 3 |omommsmso| 10 4 |12 da | |secondary |pustules |slight | 2 | 2 | so | | | | pustular| dried up;| gingivitis | | | | | | | syph | headache | following | | | | | | | | and fever| dose of | | | | | | | | gone | 1 5 c c 17 | 5 | 1 | ssmsu | 13 3 |18 da | to |tertiary. |general | | 2 | 2 | ms | | | | aortitis | condition| | 2 | 3 | ms | | | | | improved | 18 | 4 | 2 | oomm | 9 5 |13 da |- to |latent | | | 2 | 1 | mm | | | | |markedly | | | | | | | | | improved | 19 | 2 | 3 | mu | 2 5 | 5 da | |gumma | | 20 | 5 | 2 | mmmmo | 9 |14 da | to |latent |marked |small | 2 | 3 | ms | | | | | general | induration | | | | | | | | improve- | following | | | | | | | | ment | no 3 -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- corpora lutea soluble extract, parke, davis & co report of the council on pharmacy and chemistryfollowing inquiries, the council took up for consideration “corporalutea soluble extract, ” marketed by parke, davis & co in the form ofampules and proposed for hypodermic administration the report whichappears below was submitted to the council by a committee, and wasadopted by the council corpora lutea soluble extract was declaredinadmissible to new and nonofficial remedies, and publication of thereport authorized w a puckner, secretary corpora lutea soluble extract has not been submitted by themanufacturer the information of the referee is based, therefore, onthe claims made in the trade package, and on the statements in theprice list these show that the product is essentially secret andclaims made for the actions and uses of the preparation do not makeclear the essentially experimental status of the article, and aretherefore misleading conflict with rule 1 -- no definite statement of composition appearsbeyond the indefinite claim that it is an aqueous solution of “solublecorpora lutea extract, ” each ampule corresponding to 0 2 gm ofdesiccated gland how these soluble products are obtained, whether theyrepresent all the water-soluble principles, or whether essay have beeneliminated, are questions that are not answered yet such informationis essential to intelligent and scientific use, for, as there is nomethod of standardization, the method of preparation is the only markof identity for instance, we do not know at this time whether proteinshave anything to do with the supposed value of corpora lutea it is, therefore, essential to know whether or not the proteins have beeneliminated conflict with rule 6 -- the circular in the package advises thehypodermic use of this extract, not only in functional amenorrheaand the ordinary reflex consequences of physiologic or artificialmenopause, but also in. “‘neurasthenic’ symptoms during menstrual life”. “sterility, not due to pyogenic infection or mechanical obstruction”. “repeated abortions, not due to disease or mechanical factors”. “hyperemesis in the early months of pregnancy ”these are not stated merely as conditions in which various enthusiastshave tried corpus luteum, but as conditions “for which it will be foundserviceable ”it is not necessary to inform the medical profession that thisstatement is calculated to raise expectations which cannot possibly befulfilled even the manufacturers seem to realize this.

The old one with its additionof cotarnin would require a narcotic order on the other hand, therecommended dose of the cotarnin-free preparation is twenty-five tothirty-drops, whereas the product sold by bischoff and co is to begiven in doses of ten to fifteen drops-- that is, in the amount proposedfor the cotarnin-fortified product what justification is there for the claim that i don't wanna write my paper styptysate has beensubmitted to clinical tests by loewy, oppenheim and krummacher andfound to be a hemostatic par excellence and efficient even whereergot had failed to give satisfactory results?. loewy zentralblattfür gynäcologie 42:920, 1921 made essay pharmacologic tests onguinea-pigs with the cotarnin-containing preparation, but reported noclinical trials hans oppenheim medizinische klinik, aug 29, 1920, p 906 reported that he was agreeably surprised at the excellentresults vorzueglichem erfolg obtained with the drug but he did notassert that it is superior to ergot krummacher reported on thirteen paper of profuse menstruation inwhich the patients were treated with styptysate, using for a writing, the preparation containing cotarnin and for the other a preparationwithout cotarnin he reported as good results with the cotarnin-freepreparation in larger dosage, as with the cotarnin-containingpreparation in smaller dosage krummacher did not compare styptysatewith ergot essay of krummacher paper are quoted, with essaytypographical errors, in the bischoff circular on the assumption that the product discussed in german publicationsis the styptysate marketed in the united states, the best that can besaid for it is, that during a shortage of ergot it was used in placeof that established drug there is no evidence to warrant the use ofthis indefinite proprietary in place of the biologically standardizedfluidextract of ergot or other standardized ergot preparations styptysate ernst bischoff and co , inc is inadmissible to newand nonofficial remedies because its composition is semisecret andindefinite and there is no evidence that its uniformity and strengthis controlled rules 1 and 2. Further, it is inadmissible because thetherapeutic claims advanced for it are exaggerated and unwarranted rule 6 and because there is no evidence that it possesses anyadvantage over established drugs such as the biologically standardizedfluidextract of ergot or the definite ergot preparations admitted tonew and nonofficial remedies -- from the journal a m a , feb 11, 1922 lipoidal substances horovitz not admitted to n n r report of the council on pharmacy and chemistrythe council has authorized publication of the following reportdeclaring lipoidal substances horovitz inadmissible to new andnonofficial remedies because its composition is essentially secretand because the curative claims made for it are unsubstantiated and, therefore, unwarranted w a puckner, secretary in the advertising of the horovitz biochemic laboratories co a s horovitz, president we read. “horovitz proves by careful paralleled investigations of normal and of pathological tissues, both in addiction disease and in other diseases, that in patients suffering from narcotic addiction disease there is an inactivity of the lymph-glands due to the use of the drug and that the system is not supplied with the necessary fats ” “horovitz further found that the lipoidal content of the cerebro-spinal system varies in strict accordance with the pathological processes introduced by infection or by alkaloids furthermore, he has found that the lipoids of various other organs, as well as those of the thermornervous system, may be extracted and consumed by the administration of narcotic alkaloids ”it is further stated in the advertising that. “after a long and very careful research investigation, dr horovitz worked out a method of rational treatment for narcotic addiction disease which involves the restoration of the lipoids, which have been lost through the action of the drug, and of the toxins, by means of a combination of lipoidal substance from various plant lipoids in the form of a sterile solution this preparation not only replaces the lipoids lost by the tissues, but also protects the nerve tissues, from attacks by the toxins elaborated during the use of narcotics, and, this by detoxicating the tissues, brings about permanent freedom from the craving of narcotics, instead of the temporary relief afforded by other methods of treatment ”the “combination of lipoidal substance of various plant lipoids” whichwas worked out by horovitz, the horovitz biochemic laboratories offeras “lipoidal substances ” this preparation is supplied in ampoules saidto contain 1 c c of solution the treatment with “lipoidal substances”consists, first, in the complete withdrawal of the narcotic. Second, in free catharsis.

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Its concern is with the finished products on the other hand, the council requires that the information becomplete and accurate as to medicinal ingredients unofficial constituents -- unofficial constituents of proprietarymixtures must be presented by the manufacturer in the regular way andmust be acted on by the council before i don't wanna write my paper the preparations containing themcan be accepted fraud -- when it appears that a manufacturer has made a deliberatelyfalse statement concerning a product, he is asked to furnish anexplanation. And if this is not satisfactory, the product will not beaccepted, even if the false statement is subsequently corrected oromitted testimonials -- the foregoing paragraph applies not only to statementsmade to the council, but also to statements furnished to physicians bythe manufacturer or his agents, even when these statements are in theguise of testimonials explanation of rule 2. Identificationin order to avoid errors in the case of chemical compounds, and toguard against adulterations, lack of potency or strength, and themistaking of one chemical for another, it is necessary to have at handsuitable tests tests, etc -- if these facts have appeared in the literature, orin standard textbooks, reference to them will be sufficient. Butwith new chemicals, especially synthetics, the manufacturer or hisrepresentatives will be required to supply such tests for publication, as will assure an intelligent opinion of these products physiologic standardization -- in paper in which chemical methods ofidentification are unknown or unreliable, physiologic standardizationshould be employed the council considers the phrase “physiologicallystandardized” or “assayed” as misleading unless the standard andmethod are published in sufficient detail to permit of their controlby independent investigators it is evident that when no standard ispublished, it is impossible to know whether the quality is high orlow, and the conscientious manufacturer who sets for himself a highstandard is placed on a level with the dishonest or careless one whoadopts a low standard again, if the process of standardization isnot published, it is impossible to learn, without actual trial, therelative value of one preparation as compared with that of anothermanufacturer, or to confirm or disprove the statements of themanufacturer as to the quality of his product standardization of disinfectants and germicides -- no disinfectant orgermicide of the phenol type will be accepted for new and nonofficialremedies whose phenol coefficient, determined according to the methodof the hygienic laboratory, u s p h s , is not stated on the labelof the preparation explanation of rule 3. Direct advertisinglay advertising -- the impossibility of controlling the irresponsibleclaims which are usually made in advertisements to the public, thewell-known dangers of suggesting by descriptions of symptoms to theminds of the people that they are suffering from the thesis diseasesdescribed, the dangers of the unconscious and innocent formation of adrug habit, and the evils of harmful self-medication, including thedangers of the spread of thesis infectious and contagious diseases whenhidden from the physician, and similar well-known considerations, arethe reasons for discouraging, in the interest, and for the safety, ofthe public, this reprehensible form of exploitation advertising inmedical journals, etc , distributed solely to physicians, does not comewithin the scope of this rule exceptions -- in the case of subjects on which the public should beinstructed, as the use of disinfectants, germicides, antiseptics andfoods, advertisements to the public, if not in objectionable forms, are considered admissible in no case shall such advertisementsinclude recommendations for use as curative agents, nor shall thenames of any diseases be mentioned in exploitation if the preparationis sufficiently toxic to require caution in its use to preventpoisoning, this fact shall be stated on the label on account of thedeplorable results which would follow any abuse of this privilege, theconscientious cooperation of manufacturers and their agents in adheringstrictly to the limitations laid down is asked. And for the same reasonthe acceptance of an article which is so advertised as to infringe onthese limitations in any essential way as by naming diseases or bymaking false and exaggerated claims shall be summarily rescinded, and the reasons for such action may be published without notice tomanufacturer or agent a disinfectant, germicide or antiseptic willbe accepted for description in new and nonofficial remedies, and anarticle of this class which has already been accepted will continueto be included in new and nonofficial remedies only on the explicitunderstanding by the manufacturer and agent that such infringements ofthe rule will be followed by deletion of the article and by publicationof the facts as described foods -- we may divide the foods into three groups the first groupcontains the ordinary foods, including the well-known breakfastfoods these do not come under the supervision of the council inany way the second group includes a large and important class ofmanufactured products, such as invalid and infant foods, which in asense stand between the first and third groups the public has thesame interest in these foods that the physician has, and usually issupplied with full information concerning them while the primaryrecommendation of these articles should naturally come from thephysician, it cannot be expected that their continued use shoulddepend on repeated prescriptions information concerning this groupof foods would come naturally and properly from a physician, and thecollection and dissemination of this information may very properly beincluded in the work of this council as the products in this classare used extensively, it is not proper to limit their advertisingto medical journals, but the advertising should be permitted in thelay press so long as it is conducted in a manner compatible withthe rules of the council the third group includes medicinal foodsproper, such as predigested foods these have a relatively low foodvalue and are characterized by a high alcohol or preservativecontent they frequently contain strictly medicinal substances, orfood substances for which distinct therapeutic properties are claimed these products should be used only on the advice of the physician, andthe advertisements should be restricted as in the case of ordinarymedicines advertisements in foreign countries -- the council deals primarily, inthe interest of the public and of the medical profession, with articlesproposed for admission to new and nonofficial remedies, and, indetermining the status of any article, must take into consideration anystatements made regarding it or any method of advertising it employedby the manufacturer or his authorized agents or representatives, whether in this country or abroad the council will not regard aswithin its scope, however, questions concerning the marketing ofarticles except the matter of direct advertising to the laity andunwarranted claims or misrepresentations in any country which has apublic body corresponding to this council explanation of rule 4. Indirect advertisingmatter distributed solely to physicians -- it should be rememberedthat the sole intent of this rule is to protect the physician, sothat in prescribing a proprietary medicine he shall not unconsciouslyadvertise proprietary preparations the rule imposes no restriction onthe legitimate methods of bringing a remedy to the attention of theprofession, such as advertising in medical journals, circulars andother printed matter distributed solely to physicians the rule appliesonly to the package as it may reach the patient naming diseases on labels -- the naming of diseases on the labelor package is not necessary, as is shown by the very large numberof proprietary products which have been successfully introducedwithout resorting to this expedient this method of popularizing aproprietary remedy with the laity is most objectionable, and should notbe tolerated in any form in general, therapeutic indications shouldbe omitted from the label and package the council will not insiston this point, however, when such indications are so given as not topromote self-medication, writingicularly in diseases which require expertdiagnosis and supervision it will be considered an infringement ofthe rule if an article be marketed in bottles which have the name ofthe article blown into the glass, or if otherwise the name or initialsor other distinctive mark of the article is permanently stamped onthe container, on the article itself, or is on the stoppers or seals articles which are marketed in any of these ways are not acceptedfor new and nonofficial remedies readily removable labels are notobjectionable, nor is the permanent affixing of the firm initials orname to the trade package if such initials or name is not suggestive ofthe article the council does not countenance the use of an acceptedarticle for advertising other articles which have not been accepted bythe council explanation of rule 5. False claims as to originsource -- no false or misleading statement in regard to an article canbe permitted concerning the source of material from which it is made, or the persons by whom it is made essay glaring frauds of this naturehave been perpetrated in the past, and this rule is intended to preventsuch imposition explanation of rule 6. Unwarranted therapeutic claimstherapeutic questions -- this rule insists that the claims ofmanufacturers or agents concerning the therapeutic properties of theirproducts must be compatible with demonstrable facts manufacturerswill be held responsible for all statements made or quoted in theiradvertising “literature” regarding their products recognizing theexistence of honest differences of opinion on thesis therapeuticquestions, the council desires to be liberal in the application ofthis rule it is natural that a manufacturer should be writingial towardhis own product, and a moderate degree of emphasis in advertising maynot be objectionable the council, however, will not admit claims whichare neither in harmony with already accepted facts nor supported byacceptable evidence in doubtful paper the council considers thesequestions with the advice and cooperation of its staff of clinicalconsultants clinical evidence -- to be acceptable, the clinical evidence mustoffer objective data with such citation of authority as will enable thecouncil to confirm the facts and establish the scientific value of theconclusions drawn clinical data are worthless when the author is notcited the facts on which claims with regard to the value of a remedyare based must have been rendered accessible for investigation andconfirmation by disinterested observers, either through publication orthrough the records of a hospital or other institution explanation of rule 7.