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Makes men sober, solid, and staid, fit for essay format mla study. Stays the unbridled toys of lustful blood, stays the wandering thoughts, and reduces them home to the centre. Itsreceptacle is in the spleen, and it is governed by saturn of all these humours blood is the chief, all the rest are superfluitiesof blood. Yet are they necessary superfluities, for without any ofthem, man cannot live namely. Choler is the fiery superfluities. Flegm, the watery;melancholy, the earthly animal the third principal virtue remains, which is animal. Itsresidence is in the brain, and mercury is the general significator ofit ptolomy held the moon signified the animal virtue. And i am ofopinion, both mercury and the moon dispose it. And my reason is, 1, because both of them in nativities, either fortify, or impedite it 2, ill directions to either, or from either, afflict it, as good oneshelp it indeed the moon rules the bulk of it, as also the sensitivewriting of it.

Or advertisementsof medical business in which essay format mla untruthful and improbable statements aremade. Or advertising any medicine or means whereby the monthly periodsof women can be regulated, or the menses re-established if suppressed;or the conviction of any offence involving moral turpitude. Or habitualintemperance 4 in case of a refusal or a revocation of a license, the board isrequired to file a brief and concise statement of the grounds andreasons thereof in the office of its secretary, which, with thedecision of the board in writing, shall remain of record in saidoffice before a license can be revoked for unprofessional ordishonorable conduct, a complaint of essay person under oath must befiled in the office of the secretary of the board, charging the actsof unprofessional or dishonorable conduct and the facts complainedagainst the accused in ordinary and concise language, and at least tendays prior to the hearing the board shall cause to be served upon theaccused a written notice and a copy of such complaint containing astatement of the time and place of the hearing the accused may appearat the hearing and defend in person or by counsel, and may have thesworn testimony of witnesses taken and present other evidence in hisbehalf, and the board may receive arguments of counsel 5 in case of refusal or revocation of a license by the board, there isa right of appeal within thirty days after the filing of the decreein the office of the secretary, to the superior court in and for thecounty in which was held the last general meeting of the board priorto the refusal of the license, in case of refusal. And to the superiorcourt in and for the county in which the hearing was had upon whichsuch license was revoked, in case of revocation the person desiringto appeal must serve or cause to be served on the said secretary awritten notice of appeal containing a statement of its grounds, andmust file in the said secretary office an appeal bond with a goodand sufficient surety to be approved by the secretary of the stateof washington, conditioned for the speedy prosecution of such appealand the payment of such costs as may be adjudicated against him uponsuch appeal said secretary must within ten days after service of saidnotice and filing, and the approval of the said appeal bond, transmitto the clerk of the court to which the appeal is taken a certifiedcopy, under the seal of the board, of the decision and the grounds, incase of refusal, and in addition a certified copy under said seal ofthe complaint, in the case of revocation, with the bond and notice ofappeal the clerk must thereupon docket such appeal causes and theystand for trial in all respects as ordinary civil actions, and likeproceedings are had thereon on appeal the cause is tried de novo either writingy may appeal from a judgment of the superior court to thesupreme court in like manner as in civil actions within sixty daysafter the rendition and entry of such judgment if the judgment be infavor of the writingy appealing from the decision of the board, and theexamining board does not appeal within sixty days, in that case at theend of sixty days the board shall immediately issue to the successfulwritingy the usual license, and in addition reinstate upon its recordsthe name of such successful applicant, in case of revocation in caseof appeal to the supreme court by the board, no such license shall beissued nor re-instatement required until the final determination of thecause in case the final decision of the supreme court be against theboard, then the said court shall make such order as may be necessaryand the board shall act accordingly no appeal bond can be required ofthe board, nor any costs adjudged or taxed against the same s 6 filing authority - the person receiving a license must file it, or acopy, with the county clerk of the county where he resides, and thecounty clerk is required to file said certificate or copy and entera memorandum thereof, giving its date and the name of the person towhom it was issued, and the date of filing, and on notice to him of achange of location or the death of a person licensed or of revocation, the county clerk is required to enter a memorandum of said fact atthe appropriate place in the record in case of removal into anothercounty, the person licensed must procure from the county clerk acertified copy of the said license, and file it with the county clerkof the county to which he shall remove, with like effect as an originallicense 7 penalty, definition - to practise medicine or surgery without a licenseor contrary to this chapter is a misdemeanor punishable with a fine offrom $50 to $100, or imprisonment in a county jail from ten to ninetydays, or both any person is regarded as practising who appends theletters “m d ” or “m b ” to his name, or for a fee prescribes, directs, or recommends for the use of any person any drug or medicine or agencyfor the treatment, care, or relief of any wound, fracture, or bodilyinjury, infirmity, or disease. But the chapter does not apply todentists regulations - the board has authority to prescribe and establish allneedful rules and regulations to carry this chapter into effect s 9 former practitioner - all persons licensed under sec 2, 289 of the lawsof washington territory, 1881, or having complied with its provisions, are to be taken and considered as licensed under this act, and thesecretary of the board is required to enter the names of such personsupon the register kept by him, as licensed physicians and surgeons ontheir written application 10 fee - to the treasurer of the board, for examination, $10 s 3 west virginia qualification - the following persons and no others are permitted topractise medicine:1 graduates of a reputable medical college in the school of medicineto which the person desiring to practise belongs such person mustpresent his diploma to the state board of health, or the two membersthereof in his congressional district, and if it be found to be genuineand was issued by such medical college as hereinafter mentioned, andthe person presenting it be the graduate therein named, the board orsaid two members, as the case may be, must issue and deliver to hima certificate to that effect, and such diploma and certificate shallentitle the person named in the diploma to practise medicine in all itsdewritingments 2 persons not graduates in medicine who had practised medicine in thisstate under a certificate issued by the state board of health prior tothe passage of the act are authorized to practise medicine in all itsdewritingments 3 a person not a graduate of medicine and who has not practisedmedicine in this state under a certificate must be examined by thestate board of health, or the two members thereof in the congressionaldistrict where he resides, or if he resides out of the state by thetwo members in the congressional district nearest to his place ofresidence, who, together with a member of the local board of health whois a physician, if there be such a member of the local board of healthof the county in which the examination is held, shall examine him andif upon a full examination they find him qualified to practise medicinein all its dewritingments, they, or a majority of them, shall grant hima certificate to that effect, and thereafter he shall have the rightto practise medicine in the state to the same extent as if he had thediploma and certificate above mentioned the members of the state boardof health in each congressional district must, by publication in essaynewspaper printed in the county in which their meeting is to be held, or if no such paper is printed therein, in essay newspaper of generalcirculation in such district, give at least twenty-one days’ notice ofthe time and place of their meeting for the examination of applicantsfor permission to practise medicine, published at least once a week forthree consecutive weeks before the day of such meeting this section does not apply to a physician or surgeon called fromanother state to treat a writingicular case or to perform a writingicularsurgical operation in the state, or who does not otherwise practise inthe state code of w va , 1891, c 150, s 9 every person holding a certificate must have it recorded in the officeof the secretary of the state board of health, and the secretary isrequired to indorse on said certificate the fact of such recordationand deliver the same to the person named therein or his order the state board of health may refuse certificates to individuals guiltyof malpractice or dishonorable conduct, and may revoke certificates forlike causes. Such revocation being after due notice and trial by thesaid board, with right of appeal to the circuit court of the county inwhich such individual resides. But no such refusal or revocation shallbe made by reason of his belonging to or practising in any writingicularschool or system of medicine 10 the examination fee is not retained if a certificate is refused, butthe applicant may again, at any time within a year after refusal, beexamined without an additional fee, and if a certificate be againrefused he may, as often as he sees fit, on payment of the fee, beexamined until he obtains a certificate 11 examinations may be wholly or writingly in writing, and shall be of anelementary and practical character, embracing the general subjects ofanatomy, physiology, chemistry, materia medica, pathology, pathologicalanatomy, surgery, and obstetrics, but sufficiently strict to test thequalifications of the candidate as a practitioner of medicine, surgery, and obstetrics the chapter does not apply to females practisingmidwifery 12 definition, exceptions - any person is regarded as practising medicinewho professes publicly to be a physician, and to prescribe for thesick, or who appends to his name “m d ” this act also applies toapothecaries and pharmacists who prescribe for the sick it does notapply to commissioned officers of the united states army and navy andmarine hospital service 13 itinerant physician or vender - any itinerant physician or itinerantvender of any drug, nostrum, ointment, or appliance of any kindintended for the treatment of disease or injury, or who shall bywriting or printing or in any other method publicly profess to cureor treat diseases, injuries, or deformities by any drug, nostrum, manipulation, or other expedient, shall before doing so pay to thesheriff of every county in which he desires to practise a special taxof $50 for each month or fraction of a month he shall so practise insuch county, and take his receipt in duplicate therefor he shallpresent said receipts to the clerk of the county court of such county, who shall file and preserve one of them in his office and indorse onthe other, “a duplicate of this receipt has been filed in my office, ”and sign the same for such a person to practise or attempt to practisein any county without having paid such tax and filed such receipt andobtained such indorsement, or to practise or attempt to practise fora longer time than that for which he has paid a tax, is a misdemeanorpunishable with a fine of from $100 to $500 any person who shalltravel from place to place and by writing, printing, or otherwisepublicly profess to cure or treat diseases, injuries, or deformitiesis deemed an itinerant physician subject to the taxes, fines, andpenalties of this section 14 penalty - to practise or attempt to practise medicine, surgery, orobstetrics without complying with sec 9 is a misdemeanor punishable, for every offence, with a fine of from $50 to $500 or imprisonment ina county jail from one month to twelve months, or both to file orattempt to file as his own a diploma or certificate of another, ora false or forged affidavit of identity, or wilfully swear falselyto any question propounded to him on examination or to any affidavitrequired to be made and filed, is punishable with confinement in thepenitentiary from one to three years or imprisonment in a county jailfrom six to twelve months, and a fine of from $100 to $500 s 15 fee - to the state board of health, or its examining members, forexamination, $10 11 wisconsin prohibition - no person practising physic or surgery, or both, shall have the right to collect in any action in any court fees orcompensation for the performance of any medical or surgical service, or to testify in a professional capacity as a physician or surgeon, unless he shall have received a diploma from essay incorporated medicalsociety or college or shall be a member of the state or essay countymedical society legally organized in this state. Provided that in allcriminal actions the court may in its discretion and in the furtheranceof justice receive the testimony of any physician or surgeon withoutrequiring proof of the incorporation of the medical society or collegefrom which he graduated r s , 1878, s 1, 436, as amended c 131, 1887 no person practising physic or surgery, or both, prohibited by theabove section from testifying in a professional capacity as a physicianor surgeon, shall assume the title of doctor, physician, or surgeon bymeans of any abbreviation or by the use of any other word or words, letters of the alphabet of the english or any other language, or anydevice of whatsoever kind, printed, written, or painted, or exhibitedin any advertisement, circular, handbill, letter, or other instrument, nor on any card, sign, door, or place whatsoever penalty, exceptions - a violation of this act is a misdemeanorpunishable with a fine of from $25 to $100, or imprisonment in a countyjail from ten days to sixty days for each offence s 1, c 256, 1881, as amended c 40, 1882 on complaint in writing under oath before any magistrate or justice ofthe peace charging the commission of an offence against the provisionsof this act in his county, it is the duty of the district attorney toprosecute the offender, and in all such prosecutions the burden ofproof shall be upon the defendant to establish his right to use suchtitle under the provisions of this act 2 any person prohibited by sec 1 from assuming the title of doctor, physician, or surgeon who shall practise or pretend to practisephysic or surgery, or both, is not exempted from any, but is liableto all, of the legal penalties and liabilities of malpractice, andignorance shall be no excuse for a failure to perform or for neglector unskilfully performing or attempting to perform any of the dutiesrequired by law of practising physicians or surgeons the act does notprevent students from practising under the direction of a qualifiedpreceptor, nor women from practising midwifery, nor veterinarians frompractising in their special dewritingment 3 wyoming qualification - no person can lawfully practise medicine, surgery, orobstetrics who has not received a medical education and diploma fromessay regularly chartered medical school having a bona fide existencewhen the diploma was granted r s , 1887, s 1, 925 every physician, surgeon, or obstetrician must file for record withthe register of deeds of the county in which he is about to practiseor where he practises, a copy of his diploma, exhibiting the original, or a certificate from the dean of the medical school of which he is agraduate certifying to his graduation 1, 926 when filing a copy of his diploma or certificate of graduation, he mustbe identified as the person named in the paper about to be filed by theaffidavit of two citizens of the county, or his affidavit taken beforea notary public or commissioner of deeds for the state, which affidavitmust be filed in the office of the register of deeds 1, 927 penalty - to practise without complying with this chapter is amisdemeanor punishable with a fine of from $50 to $500 or imprisonmentin a county jail from thirty days to six months, or both, for eachoffence to file or attempt to file as his own a diploma or certificateof another, or a forged affidavit of identification, is a felonysubject to a fine and imprisonment in the penitentiary s 1, 928 it is the duty of the police, sheriff, or constable to arrest allpersons practising medicine, surgery, or obstetrics without complyingwith these provisions 1, 929 exceptions - this chapter does not apply to persons in emergencyprescribing or giving advice in medicine, surgery, or obstetrics ina section of country where no physician, surgeon, or obstetricianresides, or where no physician, surgeon, or obstetrician resideswithin a convenient distance, nor to persons prescribing in their ownfamilies, nor to persons claiming to practise medicine, surgery, orobstetrics in any section of the state where no physician or surgeonhaving a diploma or a certificate resides 1, 930 evidence - on the trial of persons charged with the violation ofthis chapter it shall be sufficient for the prosecution to show thatdefendant has practised medicine, surgery, or obstetrics within thecounty where the indictment is found at any time since the passage ofthe act 1876, and the defendant shall not after proof be entitled toacquittal until he shows by the testimony of essay competent witnessupon oath that the defendant has received a medical education, and agenuine diploma from essay regularly chartered medical school. Providedthat the defendant may show such facts by depositions taken in the samemanner as depositions in civil paper 1, 931 the united kingdom of great britain and ireland medical acts - the act 21 and 22 victoria, c 90, and the amendmentsthereof and additions thereto, are generally spoken of as the medicalacts medical councils - there is a general council of medical education andregistration of the united kingdom, with branch councils for england, scotland, and ireland 21 and 22 vict , 1858, c 90, s 3, 6 members of the general council are chosen as provided in 49 and 50vict , c 48, s 7. Those representing the medical corporations must bequalified to register under this act 21 and 22 vict , c 90, s 7 the general council appoints a registrar for england, and the branchcouncils for scotland and ireland appoint respectively a registrar forscotland and ireland 10, 11 registrar - it is the duty of the registrars to keep their registerscorrect, and to erase the names of all registered persons who shallhave died, and from time to time to make the necessary alterations inthe addresses or qualifications of persons registered it is lawful forthe registrar to write a letter to any registered person, addressed tohim according to his address on the register, to inquire whether he hasceased to practise or has changed his residence, and if no answer bereturned within six months from the time of sending the letter, it islawful to erase the name of such person from the register, but it maybe restored by direction of the general council 14 qualification - persons possessed of one or more of the qualificationsdescribed in schedule a, on the payment of a fee not exceeding £5, areentitled to register on the production to the registrar of the branchcouncil for england, scotland, or ireland the document conferringor evidencing the qualification in respect whereof he seeks to beregistered, or upon transmitting by post to such registrar informationof his name and address, and evidence of his qualifications and of thetime or times at which they were obtained the several colleges andbodies mentioned in schedule a may transmit from time to time to theregistrar, under their respective seals, lists of the persons who bygrant of such colleges and bodies respectively, are for the time beingentitled to register, stating the qualifications and residences of suchpersons, and it shall be lawful for the registrar on the payment of thesaid fee to enter in the register the persons mentioned in such listswith their qualifications and places of residences as therein statedwithout other application 15 the general council is required to make orders for regulating theregisters from time to time 16 persons actually practising medicine in england before august 1st, 1815, were entitled to register under the act 17 any two or more of the colleges and bodies in the united kingdommentioned in schedule a may, with the sanction and under the directionof the general council, unite or co-operate in conducting theexaminations required for qualifications to be registered s 19, 37 and 38 vict , c 34 the privy council may suspend the right of registration in respect ofqualifications granted by any college or body 21 after such revocation, no person shall be entitled to register inrespect to any qualification granted by such college before revocation22 the privy council may issue an injunction directing any body entitledto grant qualifications to desist from imposing upon any candidatefor examination an obligation to adopt or refrain from adoptingthe practice of any writingicular theory of medicine or surgery as atest or condition of admitting him to examination or granting hima certificate. And in the event of their not complying, may orderthat such body cease to have the power of conferring a right to beregistered so long as they shall continue such practice 23 where any person entitled to be registered applies to the registrarof any branch council for that purpose, such registrar is requiredforthwith to enter in a local register the name and place of residence, and the qualifications in respect of which the person is so entitledand the date of registration. And in case of the branch council forscotland or ireland, to send to the registrar of the general council acopy of the entry, and the registrar of the general council is requiredto cause the same to be entered in the general register.

“this solution contains 30 grains of the combined hypophosphites of lime and soda to the ounce it contains no sugar, no acid and it is perfectly neutral ” “indications for use -- galactostasis, imperfect metabolism, neurasthenia, nervous dyspepsia, insomnia, convalescence, acetonuria, cyclic vomiting in infants, diabetes, starvation, deficiency of lime, mother teeth during pregnancy, dentition of infants, rachitis, furunculosis, vomiting of pregnancy, obesity ” “migraine is often caused by conditions for which this solution is one of the most satisfactory remedies:” “in insomnia due to advancing age, it will often act as a hypnotic ”of the hypophosphites the schlotterbeck & foss company say. “if ‘damning it with faint praise’ on the writing of essay of the leading medical authorities, or utterly condemning it as useless, on the writing of others, would kill a medicine, the hypophosphites would long since have disappeared as medicinal agents negative testimony in regard to the value of a drug does not settle anything ”of their own preparation they say. “when we get the results that ought to follow the administration of hypophosphites, we have proved that schlotterbeck solution enters the system unchanged ” “this solution is primarily a blood and nerve tonic and chemical food ”schlotterbeck solution of hypophosphites of lime and soda is asemisecret preparation marketed under claims that are both unwarrantedand misleading robinson hypophosphitesaccording to the manufacturers, the robinson-pettet company, louisville, ky , each fluidounce of this preparation contains. “hypophosphites soda 2 gr hypophosphites lime 1-1/2 gr hypophosphites iron 1-1/2 gr hypophosphites quinin 3/4 gr hypophosphites strychnine 1/16 gr ”it is claimed to be “nutritive, tonic alterative a standard remedy in the treatment of pulmonary phthisis, bronchitis, scrofulous taint, general debility, etc stimulates digestion, promotes assimilation ”the declared composition of the preparation is unscientific, and thetherapeutic claims are unwarranted eupeptic hypophosphitesnelson, baker & co , detroit, mich , who market eupeptichypophosphites, call this preparation. “a superior combination containing the hypophosphites of potassium, calcium, iron and manganese, and the bitter tonics, quinin and strychnin, agreeably associated with natural digestive ferments of the pancreatic secretion it is thus a general reconstructive tonic the remedy is of especial value in the treatment of mental and nervous affections it is indicated in pulmonary tuberculosis, in all wasting diseases, in debilitated conditions generally and in all exhaustion from over work ”on the basis of the manufacturer statement, eupeptic hypophosphitesmust be regarded as a semisecret, unscientific, shotgun preparation, exploited through unwarranted therapeutic claims mcarthur syrup of the hypophosphites comp lime and sodaso far as the recent literature and trade package are concerned, noinformation as to the composition of this product is furnished beyondwhat is conveyed in the name the advertising for mcarthur syrup, like that for fellows’ syrup and peters’ syrupus roborans, has beenmodified as time has passed a few years ago it was advertised undersuch claims as the following. “ has stood the test during thesis years for unequaled efficacy in the treatment of tuberculosis indicated also as a tonic and tissue builder in convalescence from fevers, in nervous diseases, rickets, senile debility and bronchitis ” “its use is indicated in diseases of the chest, chronic cough, throat affections, general debility, brain exhaustion, cholera infantum and wasting diseases of children ”at present no definite claims seem to be made for it. The manufacturersevidently find the magic name of hypophosphites sufficient to evokethe spell for which the advertisement writer aid was once sought a testimonial contained in a circular which seems to be still usedillustrates both the kind of aura which surrounds hypophosphites inthe minds of physicians who are still living in the past, and the kindof logic which has made the reputation of this and thesis other equallyworthless preparations “just about six years ago i had a severe attack of la grippe which almost killed me left me with asthma catarrh and a severe cough did not get out of the house for three months took over a dozen bottles mcarthur hypophos -- came out all right and since then worked hard, but last fall took another cold, but worked on, used mcarthur hypophos , am using it now, am on my 12th bottle “i have five or six patients whom i have put on mcarthur hypophos , but i do not prescribe the single bottle, but wholesale no less than half dozen bottles one patient is on his 24th bottle with orders to get another half dozen and keep it up all winter i have given the same order to all keep it up all winter and i myself intend to do the same, for with its use i have lost no time-- rain or shine i am doing my work i know what it has done for me and what it is doing for my patients ”it would be hard to find a more characteristic example of the naïvemental processes of the simple folk who in all good faith writetestimonials for worthless medicines this well-meaning practitioner a homeopath, by the way, because he “came out all right” after anattack of grip, returns all praise to mcarthur hypophosphites, whichhe has taken “wholesale ” not the faintest doubt of the validity ofhis post hoc ergo propter hoc argument seems to glimmer across hisconsciousness mcarthur syrup of the hypophosphites is an irrational preparation while its faults are fewer and less glaring than those of essay otherproprietaries, the circulation of such a testimonial as the one justquoted is sufficient of itself to cast suspicion on the product borcherdt malt olive with hypophosphites, maltzyme with hypophosphites and maltine with olive oil and hypophosphitesthese preparations are now described in the appendix to new andnonofficial remedies borcherdt malt olive with hypophosphites borcherdt malt extract company, chicago is said to contain in each100 c c , 0 64 gm each of calcium and sodium hypophosphites, withmalt extract, olive oil and glycerine maltzyme with hypophosphites malt-diastase company, new york is said to contain, in each100 c c , 0 4 gm each of calcium, sodium and potassium hypophosphitesand 0 005 gm each of iron and manganese hypophosphites, withmaltzyme maltine with hypophosphites maltine company, brooklyn, n y is said to contain in each 100 c c , 0 64 gm each of calciumand sodium hypophosphites and 0 42 gm of iron hypophosphite, withmaltine maltine with olive oil and hypophosphites maltine company, brooklyn, n y is said to contain, in each 100 c c , 0 6 gm eachof calcium and sodium hypophosphites, with maltine and olive oil ingeneral, no therapeutic claims are made for these mixtures so far asthe hypophosphites are concerned the addition of hypophosphites tosuch mixtures is irrational and, since it tends to perpetuate thehypophosphite fallacy, detrimental to sound therapeutics the council actionthe council endorsed the conclusions of the work of dr marriottreferred to above, and noted. 1 that the therapeutic use ofhypophosphites except possibly in essay paper as a convenient means ofadministering the positive element in the salt, as ammonium in ammoniumhypophosphite or calcium in calcium hypophosphite is irrational. 2that the merits of each hypophosphite salt submitted for considerationunder the foregoing exception must be judged individually, and 3that fellows’ syrup of hypophosphites, peters’ syrupus roborans, schlotterbeck solution hypophosphites of lime and soda, robinsonhypophosphites, the eupeptic hypophosphites of nelson, baker &co , and mcarthur syrup of the hypophosphites are ineligible forinclusion in new and nonofficial remedies, and that borcherdt maltolive with hypophosphites, maltzyme with hypophosphites, maltinewith hypophosphites, and maltine with olive oil and hypophosphitesbe deleted from the appendix of n n r of these preparations, all are in conflict with rule 10. Fellows’ syrup, schlotterbecksolution, robinson hypophosphites and nelson, baker & co eupeptichypophosphites are in conflict with rule 6.

Itassuages inflammations, and swellings in wounds essay format mla. And an ointment madeof it is excellently good to heal them. There is scarcely a betterremedy growing than this is, for such as have bruised their kidneys, and upon that account discharge blood. A dram of the powder of the herbtaken every morning, is a very good remedy to stop the terms black cresses descript it has long leaves, deeply cut and jagged on both sides, not much unlike wild mustard.

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On the otherhand there is evidence that it is not innocuous, as the recentinvestigations of hanzlik and scott and their collaborators cinchophen, neocinchophen and novaspirin in rheumatic fever, j a m a 76. 1728 june 18 1921 show that it may injure thekidney the circular also contains the following. “no longer, hit and miss relief of pain at the expense of the heart, the intestines, the kidneys and the nervous system, but the promptest and most reliable analgesic, anti-inflammatory and decongestive action so far known, with notable freedom from heart depressant, renal irritant, constipating and cumulative toxic by-effects no contraindications, except chronic nephritis and the presence of kidney concretions ”this is misleading the drug depresses the circulation, injures thekidney and produces symptoms of salicylism or “toxicity ” it is notthe promptest and most reliable analgesic. Morphin is superior andsalicylate is just as efficient the phrase “decongestive action” isvague treatment of pulmonary congestion from phosgene, and congestionof the conjunctiva in mustard oil chemosis of cats, with large dosesof atophan was ineffective. In fact, it proved distinctly harmful this was shown by such workers as laqueur and magnus, and heubnerand gildemeister ztschr f d ges exper med 13:200, 1921 itis incorrect to ascribe “decongestive” or “anticongestive” action inthe true sense to atophan cinchophen the principal assets of thesalicylate-cinchophen class of drugs in the treatment of rheumatism andgout are their analgesic and antipyretic qualities the claim is made. “in rheumatic and gouty disorders, whether of the well-known muscular and arthritic type, or their eye, ear, nose and throat manifestations ”the suggestion that atophan is indicated in “their eye, ear, nose andthroat manifestations” is a vague generalization without definitemeaning, but nevertheless calculated to impress physicians and promotethe sale of atophan for common and minor ailments rhinitis and sorethroat are, of course, self-limited conditions which require chieflygood habits, personal and general hygiene as prophylactic measures, and simple hot baths with rest, instead of medication, for symptomaticrelief when it comes to ear and eye conditions, atophan certainlywould do no good in otitis media, panophthalmitis, choroiditis, retinitis, etc the administration of atophan is proposed “in migrains, hemicrania, eyestrain, etc , often vaguely grouped as ‘headaches ’” eyestrain andheadaches are vague symptoms often arising from numerous causes thatrequire no medication, but rather good habits, hygiene and similarcorrective measures there is always the possibility of habituationfrom the use of drugs for such common and vague symptoms, resultingeventually in more harm than good to the patient the use of atophan is proposed “in influenza grippe for the readyalleviation of the respiratory congestion, pain and stiffness oflimbs and back ” probably the entire claim is without warrant, sinceinfluenza is a self-limited disease atophan might relieve pain inthe joints, reduce the fever, etc , but at the same time it wouldtend to impair the functional efficiency of the heart, which may beimpaired already by the disease cardiac failure is one of the causesof death in influenza the recommendation for “alleviating respiratorycongestion” is certainly without warrant, since in actual trialin pulmonary congestion by magnus et al , atophan was found to bedeleterious and not beneficial phosgenized cats are probably as good atest object for the alleged decongestive action of atophan as anythingcould be, since, according to underhill and ringer j a m a 75:1531, 1920 the pathological physiology of the circulation andrespiration in phosgene poisoning and influenza are nearly identical further, atophan is recommended “in pyorrhea alveolaris as a systemicsupport to local and specific measures ” atophan is not indicated here pyorrhea requires local medication, if anything at all it could exertno local beneficial effects in this condition. Indeed, the employmentof atophan might lead to irritation good dental treatment is moreessential than medication finally, schering and glatz advise atophan “in eczema, pruritusand similar irritant and itching skin diseases with lowered bloodalkalinity ” the assumption that blood alkalinity is lowered inirritant and itching disease is unsupported by evidence in medicalliterature and the recommendation is incorrect and misleading neitherdoes atophan alter the reaction of the blood amelioration in thesecapricious conditions occurs without medication so that any reliefthat might be obtained could not be attributed to atophan the entireparagraph is misleading and will undoubtedly tend to extend the use ofatophan in conditions for which it is not suited -- from reports ofcouncil on pharmacy and chemistry, 1921, p 8 urotropin omitted from n n r report of the council on pharmacy and chemistryurotropin is a proprietary name applied to the substance which is knownin chemical literature as hexamethylenetetramin and which is designatedhexamethylenamine in the u s pharmacopeia the council has authorizedpublication of the following report explaining that urotropinwas omitted from new and nonofficial remedies because schering &glatz, inc the firm that markets this brand of hexamethylenaminin the united states, refused to place the u s pharmacopeianame hexamethylenamine hexamethylenamina on the label and in itsadvertising so as to make clear to physicians the identity of theproduct, and, furthermore, because it was sold under therapeutic claimswhich the council held unwarranted w a puckner, secretary commercial history of hexamethylenaminthis substance which is generally referred to in chemical literature ashexamethylenetetramin, the cyclic condensation product of formaldehydand ammonia, appears to have been described first in 1860 butlerow:ann d chem 115:322, 1860 subsequently, numerous references tothe preparation, properties and constitution of the substance appearedin chemical literature hexamethylenetetramin is said to have been first used for therapeuticpurposes by g bardet, who, in 1894, reported to the société dethérapeutique that he believed this substance to be a uric acidsolvent at about the same period, a nicolaier, who gave bardet creditfor suggesting the use of hexamethylenetetramin as a uric acid solvent, announced the discovery of its antiseptic action centralbl f d med wissensch 32:897, 1894. Deutsche med wchnschr 21:541, 1895 shortly thereafter as a result of nicolaier publication, thechemische fabrik auf aktien vorm e schering, berlin, gerthesis, beganto offer the product to the medical profession under the trademarkedand nondescriptive name “urotropine ” in the united states, it wasmarketed by schering and glatz, who then were acting as american agentsfor the schering works of gerthesis it soon became evident that hexamethylenetetramin was a valuabledrug as the substance was introduced at a time when new “synthetic”drugs were rapidly appearing and when unlimited and uncriticalconfidence was placed in them, and before the medical profession becameskeptical of the claims advanced by manufacturers for their respective“discoveries, ” it was not long before this new drug was placed on themarket by thesis firms, each applying its own name and often keeping thechemical character of it in the background essay of the names whichwere thus applied to hexamethylenamin were cystogen, aminoform, formin, uritone, urisol, {and} cystamine in 1907 the late prof j o schlotterbeck, then a member of thecouncil, protested against the confusion caused by the marketing of agiven drug under different names he stated that it was not uncommonfor a physician to prescribe two or more of these identical substancesin the same mixture, expecting to get the combined action of differenturinary antiseptics. Also, that patients had been treated first withhexamethylenamin under one name and later by the same substance underanother name the journal, jan 19, 1907, p 241 hexamethylenetetramin was admitted to the eighth revision of theu s pharmacopeia in writing because of this official recognitionand standardization and in writing because the extravagant reports ofits virtues had been largely discounted, physicians have in generalprescribed the drug by its pharmacopeial name, with one notableexception. Urotropin one reason for this is that urotropin was thefirst proprietary brand of hexamethylenetetramin introduced, a secondreason is that through the extensive and persistent advertising ofthe proprietary name under which the substance was introduced, it hasbecome firmly fixed in the minds of thesis physicians the other is thatthe product was claimed to be of greater purity than the product soldunder the pharmacopeial or other name although no evidence confirmatoryof this claim has ever been published on the other hand, danielbase, as long ago as 1907, found that hexamethylenamin sold under itspharmacopeial name is just as pure as when sold under proprietarynames when, in 1907, urotropin was admitted to new and nonofficialremedies, the published description showed that it was manufacturedby the chemische fabrik auf aktien vorm e schering, berlin, andthat schering and glatz were the united states agents in 1919, thedescription was revised to show that schering and glatz were no longerselling the german product as it is the general practice to omit articles that are admitted tothe u s pharmacopeia for the reason that their quality is guaranteedunder the federal food and drugs act and because pharmacopeialnonproprietary articles are rarely advertised with claims that requirethe council control, yet, in the case of urotropin, it was retainedbecause it was sold under a name not recognized in the pharmacopeia andbecause special proprietary claims were made for it urotropin marketed under unwarranted therapeutic claimsthe period for which urotropin stood “accepted” expired with the closeof 1921 to determine its continued eligibility for new and nonofficialremedies, the council examined the labels and circular matter sent byschering and glatz for the purpose and also a booklet “urotropin, ”subsequently sent by the firm to physicians it was found that the pamphlet contained a number of unwarrantedstatements writingicularly objectionable are the claims made for the useof urotropin as an antiseptic in body fluids that are alkaline, such asthe cerebrospinal fluid, bile, aqueous humor of the eye, saliva, theexcretions caused by middle ear infection and other excretions of thenasal, bronchial, laryngeal and mucous membranes the lack of efficacyof hexamethylenamin in alkaline secretions is generally admitted andthe clinical references to the use of hexamethylenamin in the pamphletare obsolete in the introduction to the pamphlet, schering and glatzstate that they are well acquainted with the scientific research workdiscrediting the efficiency of hexamethylenamin in nonacid mediums, but that they feel that the accumulated evidence for its efficacy insuch conditions should not be “brushed aside ” however, the pamphletis not made up of quotations, but of unqualified statements with oneexception, all references to the antiseptic properties of the drug inalkaline mediums are previous to 1913, that is, before the importanceof reaction of the medium was fully appreciated to quote theseearlier articles without regard to the later work, which in most eyesdiscredited them, constitutes in effect an exploitation of this brandof hexamethylenamin under unwarranted therapeutic claims urotropin a brand of hexamethylenamine, u s p in consideration of the confusion which arises from the applicationof different names to an identical article, the rules of the councilprovide that when an article which has been accepted for new andnonofficial remedies is admitted to the u s pharmacopeia underanother name, it will be retained, provided the official name isgiven prominence on the label and in the advertising of such article neither the label nor the advertising for urotropin gives prominenceto the pharmacopeial name as a synonym nor indeed does it bring outthe fact that urotropin is a brand of hexamethylenamine, u s p schering and glatz, inc , was advised that urotropin could be retainedin new and nonofficial remedies only on condition that the objectionsto the therapeutic recommendations were removed and on agreement thatthe u s p name appear on the labels and circular matter the firmdid not offer to make the product eligible for continued recognition;accordingly the council directed the omission of urotropin because ofconflict with rule 6 unwarranted therapeutic claims and with rule8 objectionable names -- from reports of council on pharmacy andchemistry, 1921, p 71 styptysate not admitted to n n r report of the council on pharmacy and chemistrythe council has authorized publication of the following report, declaring styptysate ernst hischoff co , inc inadmissible to new andnonofficial remedies w a puckner, secretary styptysate, according to the advertisement of ernst bischoff co , inc , new york, is “obtained by dialysis from bursa pastoris sheppardsic!.