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Outwardly applied, it takesaway the hardness of the matrix, and do my psychology homework fills hollow ulcers with flesh agnus castus, &c chast-tree the leaves are hot and dry in the thirddegree. Expel wind, consume the seed, cause chastity being only borneabout one. It dissolves swellings of the testicles, being applied tothem, head-ache, and lethargy allajula, lujula, &c wood sorrel it is of the temperature of othersorrel, and held to be more cordial. Cools the blood, helps ulcers inthe mouth. Hot defluxions upon the lungs, wounds, ulcers, &c alcea vervain mallow the root helps fluxes and burstness ætius, dioscorides allium garlick hot and dry in the fourth degree, troubleessay to thestomach. It dulls the sight, spoils a clear skin, resists poison, easesthe pains of the teeth, helps the bitings of mad dogs, and venomousbeasts, helps ulcers, leprosies, provokes urine, is exceedinglyopening, and profitable for dropsies althæa, &c marsh-mallows are moderately hot and drier than othermallows.

Deutsch med wchnschr 38:375, 1912 neuberg, caspari and löhe. Berl klin wchnschr 49:1405, 1912 269 gers, gaube du. La cuprase et le cancer, paris, 1913 inasmuch as this new type of cancer therapy derives its origin, its justification and its support, in very large measure, from thelaboratory results obtained in animals, it is a matter of considerableimportance to examine those results with care, in order to determinewhether they furnish a satisfactory basis for human therapy, andwhether they justify the hopes to which they have given rise it is safe to assert that the application of chemotherapy to thetreatment of tumors practically dates from the publications ofwassermann he stated the principle that a rational therapy of tumorsmust be based on constitutional treatment it appears evident thatlocal treatment can have only local effects the lymphatic extensionsof tumorous growths, and the often unsuspected metastases in distantorgans must of necessity escape the effects of purely local treatment hence, wassermann reached the conclusion that all treatment of cancerwhich was to be effective, and not merely palliative, must be carriedto all writings of the body by means of the blood stream he thereforeintroduced the use of intravenous injections in the experimentaltherapy of rat and mouse tumors an accidental observation led himto believe that selenium was a substance possessing a high degree ofaffinity for tumor cells in order to insure the penetration of the tumor in the live animal bythis substance, however, he considered it essential to combine it withessay other highly diffusible substance this type of substance, whichwas to act as a carrier of the selenium, he described under the name“cytotrochin, ” from the greek word τροχιά {trochia}, meaning road forthis purpose he selected eosin the eosin and the selenium were thencombined by a method and in a form the details of which have neverbeen published all that we know of this preparation is contained inthe statement that it is very difficult to produce, and that it isextremely unstable and difficult to keep mice can be given amounts offrom 2 to 3 mg of this substance in solution wassermann experimentedwith mice inoculated with transplanted tumors of the types of carcinomaand sarcoma after from three to five intravenous injections of thedrug, he noted that the tumors become softer and fluctuate after stillfurther injections the fluid mass undergoes absorption, and the tumorgives the impression of an empty sac if it is possible to carry theinjections up to the number of ten or twelve, recovery ensues in suchcured animals there remain only the unabsorbed portions of the fibrouscapsule recurrences were not observed in the cured animals wassermannfurther stated that two spontaneous tumors in mice which had beentreated by this method presented favorable results wassermann original presentation gave few experimental details, andhas not been followed by the promised scientific report from hisarticle it is impossible to determine what proportion of his animalswere cured and what proportion failed to survive the treatment from alater paper by keysser270 we learn that by far the larger portion ofthe animals perished during the treatment in the stage of softening, so that a cure was accomplished in from only 3 to 5 per cent of theanimals this is a point of great importance, inasmuch as it furnishesan indication of the highly dangerous character of this mode oftreatment fatal results are attributed by keysser to the absorption oftoxic products from the tumor this contention, however, is supportedby no observations, and it is certainly equally fair to assume thatdeath results from the toxic effects of the compound a microscopicstudy of tumors taken from animals undergoing treatment was made byhansemann he found that the death of the cells was the result ofnuclear destruction 270 keysser. Wien klin wchnschr 26:1664, 1913 within a very few months after wassermann publication, neubergand caspari268 published a paper which was the first of a seriesof studies on the therapeutic effects of the heavy metals on theanimal tumors they used zinc, platinum, tin, selenium, copper, silver and cobalt in the form of certain complex organic compounds, the composition of which is not revealed owing to the fact thatintravenous injections of these compounds produced a specific effect onthe tumors, they are described as “tumoraffin” substances immediatelyafter the intravenous injection of these preparations, there followeda marked hyperemia of the tumor, whereas the remainder of the mousebody appeared markedly anemic the hyperemia was often attendedby hemorrhage into the tumor this first stage was succeeded byliquefaction and absorption followed by recovery in favorable paper the authors failed to state in what proportion of their experiments theanimals died, and in what proportion recovery ensued the second paper on this subject is by neuberg, caspari and löhe, 268in which further details are vouchsafed they state that with thecompounds used by them the toxic and the therapeutic doses approximatevery closely, from which it follows that the treatment, as with thewassermann method, results in a very high mortality smaller dosesproduce no therapeutic effect. On the contrary, they seem to act asa stimulus to the tumor, accelerating the normal rate of growth spontaneous tumors show similar effects, but no cures are recorded only in tumors in which autolysis is active intra vitam does themethod exert any effect consequently the benign primary tumors ofanimals, such as fibromas, are not influenced by it neuberg and caspari are to a great extent responsible for the colloidaltheory of treatment in tumors accepting the observations of petri andothers that the autolytic ferments in tumors are quantitatively greaterand qualitatively different from those present in the normal tissuesof the body, they venture the assumption that the process of recoveryin the experimental tumors of animals is due to the self-digestion ofthe tumor by these ferments ascoli and izar271 had shown that suchferments are materially stimulated by the presence of metals, and moreespecially of metals in colloidal form this contention is apparentlyin harmony with the well-established fact that certain colloidal metalsof themselves are capable of acting under certain circumstances asferments neuberg and caspari were at first of the belief that thecompounds produced by them circulate in colloidal form subsequentlythey stated that these compounds were crystalline substances, but theyassumed, under the influence of the theoretical consideration mentionedabove, that these substances are broken up in the tumor and thereundergo transformation into the colloid state 271 izar. Ztschr f immunitätsforsch , 1913 izar and basile. Berl klin wchnschr , 1913, p 1312 in connection with the preceding observations there are certain otherexperimental results which require mention izar271 succeeded incuring rat tumors by means of injection of colloidal sulphur c lewin272 cured subcutaneous mouse tumors with various preparationsof gold werner and szécsi273 produced similar results througha combination of selenium-vanadium with cholin-borate. In theseexperiments the selenium-vanadium was supposed to be present incolloidal form 272 lewin, carl. Berl klin wchnschr , 1913, p 147. Berl klin wchnschr , 1913, p 541 273 werner and szécsi. Ztschr f chemotherap , 1913, orig , i, 358 szécsi.

It stays alsothe abundance of women courses. It is a singular good wound-herb forgreen wounds, to stay the bleeding, and quickly close together the lipsof the wound, if the herb be bruised, and the juice only applied it isoften used in gargles for sore mouths, as also for the secret writings the smoak hereof being bruised, drives away flies and gnats, which inthe night time molest people inhabiting near marshes, and in the fennycountries loosestrife, with spiked heads of flowers it is likewise called grass-polly descript this grows with thesis woody square stalks, full of joints, about three feet high at least. At every one whereof stand two longleaves, shorter, narrower, and a greener colour than the former, andessay brownish the stalks are branched into thesis long stems of spikedflowers half a foot long, growing in bundles one above another, outof small husks, very like the spiked heads of lavender, each of whichflowers have five round-pointed leaves of a purple violet colour, oressaywhat inclining to redness. In which husks stand small round headsafter the flowers are fallen, wherein is contained small seed theroot creeps under ground like unto the yellow, but is greater than it, and so are the heads of the leaves when they first appear out of theground, and more brown than the other place it grows usually by rivers, and ditch-sides in wet ground, asabout the ditches at and near lambeth, and in thesis places of this land time it flowers in the months of june and july government and virtues it is an herb of the moon, and under thesign cancer. Neither do i know a better preserver of the sight whenit is well, nor a better cure for sore eyes than eyebright, takeninwardly, and this used outwardly. It is cold in quality this herbis nothing inferior to the former, it having not only all the virtueswhich the former hath, but more peculiar virtues of its own, foundout by experience. As, namely, the distilled water is a presentremedy for hurts and blows on the eyes, and for blindness, so as thechristalline humours be not perished or hurt. And this hath beensufficiently proved true by the experience of a man of judgment, whokept it long to himself as a great secret it clears the eyes of dust, or any thing gotten into them, and preserves the sight it is also veryavailable against wounds and thrusts, being made into an ointment inthis manner. To every ounce of the water, add two drams of may butterwithout salt, and of sugar and wax, of each as much also. Let themboil gently together let tents dipped into the liquor that remainsafter it is cold, be put into the wounds, and the place covered witha linen cloth doubled and anointed with the ointment.

For that woulddiminish the effect of their attitude they must confine themselves toinforming the public of the facts. And to guarding the health of thepublic at large, and of their own patients in writingicular no one, in a free country, can force a diseased individual to seekeffective treatment or prevent him from using an ineffective treatment, unless his disease imperils the health of others at that point, andnot before, the government can and should take personal measures however, it is a well recognized function of the government to protectindividuals against their own ignorance it does this when it forcesthe child to go to school. It does this when it places the swindler injail on exactly the same principle, the government has the right and theduty to protect the uninformed public against the flagrant evil of thepatent medicine traffic-- and the patent medicine traffic as now carriedon is a flagrant evil and series of evils the government shouldprotect the public against advertisements that are framed to suggestor create imaginary ailments, with their attendant miseries. It shouldprotect the public against being deluded by false promises of cure;against the specious relief that merely hides the disease and blindsthe patient to its dangers.

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“k-y allays smarting and burning at once through its pronounced soothing and cooling effects, and thus makes do my psychology homework an admirable dressing for burns ” “thesis physicians make a practice of anointing the bodies of their measle and scarlet fever patients with ‘k-y, ’ in this way affording gratifying relief from itching and irritation, and effectively preventing dissemination of infectious material ”and this from another circular. “i had one of the most troubleessay paper of pruritus vulvæ that i had ever seen i guess i must have tried everything and the case had been referred to me by another man, who had previously tried everything, including cauterization well, one day i was examining her, and of course k-y on the speculum-- the irritation seemed to quiet down, and the following day she said she felt no effects from it at all then later on, it returned, and i couldn’t imagine what had done so much good, unless it could have been the lubricant, so i told her to buy a tube, which she did every once in a while she has a return of it slightly, but she just applies k-y and clears it all up ”the manufacturers state that they do not know why k-y is so soothing, but suggest. “possibly the cooling action of the combination, and the effect of the 4% boric acid contained, are factors that enter be all that as it may, the fact certainly remains that oftentimes, after other local measures fail, ‘k-y’ lubricating jelly gives relief ”elsewhere it is claimed to be germicidal, and to give relief in otherconditions, thus. “diabetic and uremic irritations, not only of the genitalia, but of other writings, have been found fully as amenable as pruritus vulvae to the soothing influence of ‘k-y’ lubricating jelly, especially if the previous application is removed with water every time a new one is put on ”the foregoing citations are obviously intended largely for the public, and make it plain that “k-y” jelly is not in the class of nonmedicaland harmless external applications. On the contrary, these claimstend to create the impression that the spread of measles and scarletfever can be prevented in the stage of desquamation to placesuch statements in the hands of the patient supported by the tacitendorsement of a prescription is to create a false and dangeroussense of security and to lead to a failure to observe other and moreimportant means of preventing dissemination of these diseases the council held k-y lubricating jelly in conflict with rules 1, 4, 6and 10, and authorized publication of this report -- from the journala m a , sept 29, 1917 ziratol report of the council on pharmacy and chemistryziratol bristol-myers company, new york, in compliance with thefederal “insecticide law, ” is declared to contain 32 per cent waterand 30 per cent glycerin as inert constituents regarding its activeconstituents the manufacturer makes the following and meaninglessstatement:“ziratol is prepared from phenols of the naphthalene series andconsists of a solution of such phenols in a mixture of soap, water andglycerin ”in response to inquiry, the a m a chemical laboratory examinedziratol and reported that its essential constituent appears to bealpha-napthol, 120 and that it has, essentially, the followingcomposition by weight. Alpha-napthol 18 per cent , soap 20 per cent , glycerin and water sufficient to make 100 per cent 120 alpha-napthol was also found to be the basisof the nostrum benetol see the journal, april 15, 1911, p 1128 a ziratol advertising circular gives a tabulated report of germicidaltests, said to have been made according to the method of the hygieniclaboratory of the u s public health service when this work wasdone is not stated according to these tests ziratol possesses aphenol-coefficient of 13 66 the claim that ziratol is ten times moreefficient than carbolic acid phenol is evidently based on this report these claims of high germicidal value are contradicted by anexamination made for the council a specimen purchased in the openmarket was examined independently by two operators, to determine thehygienic laboratory phenol-coefficient one observer found the phenolcoefficient to be 2 54 the other reported it to be 3 09 evidently thegermicidal value of ziratol is greatly exaggerated in the advertisingclaims and, in fact, does not exceed that of the official compoundsolution of cresol liquor cresolis compositus, u s p for whicha phenol-coefficient of about three has been established see newand nonofficial remedies, 1917, p 82 the claim that ziratol is“the universal antiseptic and germicide” is manifestly an unwarrantedexaggeration the referee in submitting this report to the council recommended thatziratol be held in conflict with rule 1 secrecy of composition andrule 6 unwarranted and exaggerated claims after the report had beensubmitted, it was found that a new advertising circular, accompanyinga trade package, no longer contained the claim that “ziratol is tentimes more efficient than carbolic acid ” the older circular made thefollowing statement. “1 strong activity -- compared with the bactericidal action of carbolic acid by the method of the hygienic laboratory of the marine hospital service, ziratol has the carbolic acid coefficient of more than ten, that is, ziratol is ten times more efficient than carbolic acid, -- a strength unapproached by any other of its class ziratol in dilution of 1:1400 kills the typhoid bacillus in 2-1/2 minutes, thus proving that it is strongly active even in very weak solutions ”the new advertising circular reads. “1 strong activity-- extensive bacteriological investigations on thesis pathogenic organisms, conducted in the lederle laboratories of new york, prove conclusively the high bactericidal value of ziratol in extremely dilute solutions a copy of the complete report will be mailed upon request ”in response to a request, the bristol-myers company sent a copy ofthe bacteriologic investigations of ziratol, said to have been madeby the lederle laboratories the organisms employed for these testswere staphylococcus aureus, staphylococcus albus, streptococcus, green pus bacillus, b coli, and saliva no tests are given with thetyphoid bacillus the conclusion is reached that “in all the tests thesolutions of ziratol have several times greater killing efficiencythan those of phenol ” the “coefficients” or comparative values whichcan be calculated from the results after exposure of 15 minutes to thedisinfectants range from 2 0 to 4 0 this is in substantial accordwith the referee findings as regards the phenol-coefficient with b typhosus as the test object while the new advertising circular avoidsthe former claim that ziratol is ten times more efficient than carbolicacid, in germicidal value, it still makes the unwarranted claims thatziratol is the “universal disinfectant ”the council declared ziratol inadmissible to new and nonofficialremedies 1 because its composition is secret rule 1. 2 becausethe phenol coefficient, determined according to the method of thehygienic laboratory, u s p h s , is not stated on the label rule2. 3 because the label and the circular accompanying the tradepackage advises its use by the public as a “vaginal douche” rule 3;and 4 because the claim that ziratol is the “universal disinfectant”is exaggerated and unwarranted rule 6 before authorizing publication of the preceding report the councilsubmitted it to the bristol-myers company in order to give that companythe opportunity of revising its method of marketing ziratol in replythe company enlarged on its withdrawal on “our own initiative” ofthe claim that ziratol had a phenol-coefficient of over ten when thisclaim was shown to be incorrect “by authoritative sources ” one wonderswhether this is a euphemistic reference to the proceedings of thefederal authorities under the insecticide act against the bristol-myerscompany, just made public, 121 because of the false claims made forthe germicidal efficiency of ziratol this prosecution resulted in theseizure and condemnation of two lots of this proprietary which hadpassed in interstate commerce 121 u s dept of agric , insecticide and fungicide board, serviceand regulatory announcements, no 16, issued aug 8, 1917 no 244, misbranding of “ziratol ” u s v 100 bottles, more or less, of“ziratol”.