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Whethersuch study was in an institution of learning and, if so, its name andlocation. If not in such institution, where and under whose tutorshipsuch study was prosecuted, the time engaged in the actual practice, if at all, of medicine and surgery or either, and where, and the ageof the applicant at the time of the application, such applicationand affidavit to be filed and preserved of record in the office ofthe secretary of the board at the time and place designated bythe board or at a regular meeting of the board, applicants must beexamined in anatomy, physiology, chemistry, histology, materia medica, therapeutics, preventive medicines, the practice of medicine, surgery, obstetrics, diseases of women and children, of the nervous system, ofthe eye and ear, medical jurisprudence, and such other branches asthe board deem advisable the examination must be both scientific andpractical, and of sufficient severity to test the candidate fitnessto practise medicine and surgery, by written or printed, or writinglywritten and writingly printed, questions and answers, and the same arerequired to be filed and preserved of record in the said secretaryoffice after the examination, if it be satisfactory, the board shallgrant a license, by the consent of not less than five members, exceptas hereinafter provided refusal or revocation - the board may refuse or revoke a license forunprofessional or dishonorable conduct, subject to the right of appeal3 “unprofessional or dishonorable conduct” means. Procuring or aidingor abetting in procuring a criminal abortion. Or employing what arepopularly known as cappers or steerers. Or obtaining any fee on theassurance that a manifestly incurable disease can be permanentlycured. Or wilfully betraying a professional secret. Or advertisementsof medical business in which untruthful and improbable statements aremade.

This on no other ground really than the opinion “that they have no advantage over the simple preparations themselves ” naturally we shall continue to prepare these products and shall continue to take such action as we deem best to bring them to the attention of the physician, for the conduct of our business must remain in the hands of those who are personally responsible for it and it is now forty years since we took up this line of work and with the declared intention of devoting ourselves to the applied science of the digestive ferments and “to their development and practical application in every useful purpose in medicine ” we have been consistently in sympathy with the fundamental purpose of the council, which must first rest upon fact as to the character of the products offered as medicinal agents the weight of evidence justifies the position that these writingicular products rationally should be, and as a matter of fact are, of important special service in the utilization of these organic secretions in medicine as explained in the preceding report, the council holds that complexmixtures of remedial agents are from every point of view inimicalto therapeutic progress and therefore to the public welfare theyare custom writing services such especially objectionable because it is impossible to determineaccurately the effects which follow the simultaneous administrationof a number of drugs having dissimilar actions, and because such apractice tends strongly to discourage careful consideration of thespecial needs of individual patients without which there can be notherapeutic progress on the contrary, with their use, therapeutictreatment becomes haphazard and mere guesswork the dismissal of the holadin and bile salts mixtures does not involvethe question of the usefulness of holadin or of bile salts alone. Onthe contrary, the possible usefulness of these preparations is admittedin the report it is the combination of holadin, bile salts, sodiumsuccinate and phenolphthalein to which objection is made the statement of fairchild bros and foster that “these combinationsare now further justified in view of physiological considerations”is essaywhat misleading it is true that bile and the pancreaticsecretion cooperate in intestinal digestion, but there is no evidencethat in every case in which there is a deficiency of one of thesesecretions there is also a deficiency of the other, and it is an axiomof scientific therapeutics that no drug or remedial agent should beadministered except to fill a definite want otherwise the practice oftherapeutics becomes mere empiricism the properties of phenolphthalein are not in the least influenced bythe manner of its introduction, as messrs fairchild bros and fosteremphasize. But the important fact in this connection is that thepopular conception of their actions is greatly influenced by the modeof introduction, and phenolphthalein has been widely advertised in avariety of conditions, so that the popular notion concerning it is notthat of scientific therapeutics in short, the entire argument of messrs fairchild bros and fosterconcerning the exploitation of these preparations may be summed up bysaying that they have been used by clinicians who believe that goodresults have followed their use, and that the firm will thereforecontinue to supply the demand the tendency of essay to use anythingbrought to their notice, and the readiness of manufacturers to marketanything that physicians will use, presents the greatest obstacleto therapeutic progress there was never a nostrum so irrational orworthless that honest but undiscriminating clinicians could not befound who reported wonderful results from its use according to fairchild bros and foster, these holadin and bile saltsmixtures have been in use for essay nine years yet the council is notaware of any investigation of their merits that meets the requirementsof scientific research the council is not acquainted with a single clinical investigation oftheir action under conditions which afford satisfactory evidence oftheir therapeutic value it is obviously wholly insufficient for a clinician to report that theuse of a mixture was followed by good results the fallacy of sucharguments was demonstrated long ago he must make a comparison of theresults obtained with the remedial agent with those obtained in asnearly similar conditions as possible except for the use of the agent we are not aware that any such study of the mixtures in question hasbeen made it is in the last degree irrational to hold that becausebile salts are the active constituents of bile, therefore such complexmixtures as these are necessary -- from reports of council on pharmacyand chemistry, 1918, p 59 liquor santaiva, s & d , omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of liquor santaiva, s & d , has been authorized forpublication w a puckner, secretary so far the council has applied rule 10 concerning the recognition ofmixtures with the greatest leniency compatible with consistency whenthere has been a reasonable doubt concerning the value of a mixture, ithas frequently directed that rule 10 should not apply, pending furtherclinical trial of such mixture in no instance has subsequent experience shown that a strictinterpretation of the rule would have worked hardship or injustice thecouncil feels that there is no longer any warrant for the admission ofcomplex mixtures to new and nonofficial remedies or for the retentionof any that have been admitted, unless definite evidence of thetherapeutic value of such combinations is available the council being engaged in the annual revision of new and nonofficialremedies, the referee in charge of santal preparations reported thatthe three year period of acceptance had expired for liquor santaiva sharp & dohme the referee held that liquor santaiva, s & d , declared to be asolution of santal oil and copaiba with aromatic oils, in a mixtureof alcohol and water, is plainly in conflict with the currentinterpretation of rule 10, because there was no sound evidenceto indicate that any useful end is gained by the simultaneousadministration of santal oil and copaiba in any proportion, and thatso, of course, there is no evidence of the special advantage in thefixed proportions represented by the mixture he pointed out that theformula is essentially a survival of the discredited shotgun gonorrheamixtures and therefore recommended that its acceptance be not continued the council agreed to the recommendation of the referee and directedthat liquor santaiva, s & d , be omitted from new and nonofficialremedies -- from reports of council on pharmacy and chemistry, 1918, p 66 maltzyme, maltzyme with cascara sagrada, maltzyme with cod liver oil, maltzyme ferrated and maltzyme with yerba santa omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of the maltzyme preparations has been authorized forpublication w a puckner, secretary in 1916, the council voted to omit maltzyme with hypophosphites, andmaltzyme with phosphate of iron, quinine and strychnine at thattime the labels used on the maltzyme preparations still in new andnonofficial remedies contained a list of maltzyme combinations whichincluded those which had been dismissed as the council does not permitan accepted article to be used as a means of advertising an articlenot accepted, it voted to continue the following preparations fora period of three years on condition that reference to the deletedarticles be omitted from the labels when those then in stock had beenused up. Maltzyme, maltzyme with cascara sagrada, maltzyme with codliver oil, maltzyme ferrated and maltzyme with yerba santa while themaltzyme company made no definite agreement to revise its advertisingpropaganda in accordance with the council requirements, the maltzymepreparations were retained in the belief that in due time the requiredrevision of the labels would be made the council being engaged in preparing the 1919 edition of new andnonofficial remedies, the referee in charge of malt extracts reportedthat the maltzyme company had not revised its labels in accordance withthe stipulation of the council the referee further reported he hadbecome convinced that the claim that maltzyme is “rich in malt enzymes”is unwarranted and that the term “maltzyme” malt plus enzyme ismisleading. This because of the recognized instability of malt extracts jour a m a , march 30, 1912, p 954 and because the maltzymecompany makes no definite statement with regard to the diastase maltenzyme content of its preparations 126 for this reason it hadbeen the referee intention to propose the deletion of all maltzymepreparations when their period of acceptance expired in 1919 as, however, the present maltzyme preparations are in contravention withthe council requirements, he recommended that the acceptance of thesepreparations be canceled now 126 manufacturers are warned by the dewritingment of agriculture, through the bureau of chemistry, that combinations claiming to containdigestive enzymes must be active when sold if preparations tend todeteriorate in a short time, each lot should be dated and not soldafter the period when they become inactive while every manufacturermust be considered innocent until proved guilty, and ignorant untilproved knowing, it is a matter of knowledge that manufacturers havemarketed their various digestive mixtures with full appreciation oftheir worthlessness -- jour a m a , dec 19, 1914, p 2234 the council agreed to the recommendation of the referee and directedthat maltzyme, maltzyme with cascara sagrada, maltzyme with cod liveroil, maltzyme ferrated, and maltzyme with yerba santa be omitted fromn n r -- from reports of council on pharmacy and chemistry, 1918, p 67 methaform omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of methaform has been authorized for publication w a puckner, secretary methaform is the proprietary name applied by f stearns & co tochlorbutanol being engaged in the annual revision of new and nonofficial remedies, and the term of acceptance for methaform having expired, a tradepackage was purchased to determine if the product was marketed incompliance with the rules of the council it was then found that acircular was wrapped with the trade package which advertised methaforminhalant, a preparation not accepted for new and nonofficial remedies for obvious reasons, the council does not countenance the use of anaccepted article as a means of advertising an article not accepted accordingly f stearns & co was advised that the council wouldbe obliged to withdraw the acceptance of methaform unless theobjectionable circular was omitted from the methaform packages stearns & co did not give the requested assurance, and therefore thecouncil directed that methaform be omitted from new and nonofficialremedies -- from reports of council on pharmacy and chemistry, 1918, p 68 pineal gland, red bone-marrow and thymus gland and their preparations omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of pineal gland, red bone-marrow and thymus gland and theirpreparations has been authorized for publication w a puckner, secretary pineal gland, red bone-marrow and thymus gland were admitted to newand nonofficial remedies when these products gave promise of havingtherapeutic value the term of acceptance for the preparations of pineal gland, redbone-marrow and thymus gland having expired, the referee in charge ofanimal organ preparations recommended in his report for the annualrevision of n n r that these products and the general articlesdescribing them be omitted from new and nonofficial remedies he heldthat the experimental and clinical experience with them leads to theconclusion that they are without value in accordance with the recommendation of the referee, the council votedthat the following preparations be omitted from new and nonofficialremedies. Desiccated pineal gland-armour. Pineal gland tablets-armour;extract of red bone-marrow-armour. Desiccated thymus-armour. Thymustablets-armour as a matter of record, the descriptive articles for pineal gland, redbone-marrow and thymus gland, which appeared in new and nonofficialremedies, 1918, are given below pineal glandthe functions of this gland have not yet been established but thereis essay pathological and essay experimental evidence that there isa relation between the gland and essay processes of development andgrowth. The nature of this relation is unknown adiposis is a frequentsign of disturbed pineal function, but observers are not agreed whetherto interpret this as indicating hypofunction or hyperfunction, orpossibly a concurrent disturbance of the pituitary in essay instancesintravenous injections of pineal extract have seemed to cause adistinct fall in blood pressure it has been inferred from observationsin paper of pineal tumors in the young that the gland in youngindividuals furnishes a secretion which inhibits growth, writingicularlythe development of the reproductive glands, but the results ofexperimental administration of pineal substance orally have led otherobservers to infer that the pineal secretion favors physical andpossibly mental and sexual development it has been suggested that, asall evidence points to the fact that the function of the pineal glandis one of early life, extract of adult pineal glands might be expectedto be inert experiment has also indicated greater activity in glandsobtained from young animals than in those obtained from older ones thecouncil has decided to admit preparations of pineal gland to new andnonofficial remedies simply for experimental purposes red bone-marrowred bone-marrow consists largely more than 90 per cent of fat innew-born animals a third or more of this fat consists of lecithin the marrow of the bones of new-born animals contains iron up to 1per cent or more in various forms of organic combination bothlecithin and iron decrease rapidly in the first weeks after birth the commercial preparations contain very variable amounts of theseconstituents actions and uses -- red bone-marrow is supposed to stimulate theformation of red blood corpuscles. Whatever action it may have in thisdirection is probably due largely to the iron and lecithin which itcontains it is said to be useful in simple and pernicious anemias thymus glandlittle is known as to the functions of the thymus, but it is believedto have an important relation to growth there also seems to be essayrelation between the thymus and thyroid, for the former is frequentlyabnormal in diseases involving the latter hyperthyroidism the use of thymus is purely empirical it has been employed in thetreatment of hyperthyroidism, rickets, tuberculosis, hemophilia, andinfantile marasmus and atrophy. Its use in the latter conditionsis said to be the most promising it is claimed on very doubtfulgrounds to exert a essaywhat favorable effect in certain paper ofcancer -- from reports of council on pharmacy and chemistry, 1918, p 69 piperazine and lycetol omitted from n n r report of the council on pharmacy and chemistrythe following report explaining the omission from new and nonofficialremedies of piperazine and lycetol has been authorized for publication w a puckner, secretary piperazine diethylenediamene and lycetol a methyl derivative ofdiethylenediamene were accepted for new and nonofficial remedies in1906 both piperazine and lycetol were asserted to be efficient uricacid solvents and efficacious remedies in the treatment of gout andrheumatism these products have been retained until now because therewas no investigation which definitely showed their uselessness as uricacid solvents, though their use is generally admitted to have beendisappointing from an exhaustive and critical study of the available evidence, hanzlik jour lab & clin med , february, 1917 concluded thatscientific evidence, though limited, and clinical opinion indicate thatpiperazine is valueless in gout and that there is sufficient scientificevidence to indicate the worthlessness of lycetol the referee in charge of piperazine and lycetol recommended that theseproducts be omitted from new and nonofficial remedies for the reasonthat they have been sufficiently tried to justify the conclusion thatthey are not of value the period of acceptance having expired, thecouncil directed that piperazine and piperazine tablets the bayercompany, inc and lycetol the bayer company, inc be omitted fromnew and nonofficial remedies -- from reports of council on pharmacyand chemistry, 1918, p 70 stanolind liquid paraffin omitted from n n r report of the council on pharmacy and chemistryas explained in the report which follows, “stanolind liquid paraffin”was omitted from new and nonofficial remedies at the request of theproprietors announcement of this omission was made in the preface tonew and nonofficial remedies, 1918, but publication of the councilreport was postponed pending actual conflict with the rules thecouncil now authorizes publication of the report because a circularindirectly advertising the product to the public was found enclosedwith the trade package of stanolind liquid paraffin w a puckner, secretary stanolind liquid paraffin was admitted to new and nonofficial remediesin 1916, when its method of marketing conformed to the rules of thecouncil this brand of liquid petrolatum, by action of the council, has been omitted from new and nonofficial remedies on request of thestandard oil company of indiana, its manufacturer, who wrote to thesecretary of the council stating that. “in order that our facilities for the manufacture of this oil shall be constantly engaged, it will be necessary for us to find sales on a larger scale than in the past to do this under our present advertising and marketing arrangement we feel will be impossible ”this letter, in addition, suggested “that physicians are notprescribing stanolind liquid paraffin in any considerable proportionof their orders” and “that the situation which now confronts us wouldnot be materially helped if stanolind was specified in all suchprescriptions ” further, the council is asked to consider whetherit “might be willing to declare this preparation as not a councilproduct, ” on the alleged grounds that “liquid paraffin is not medicinalin its action and passes through the digestive tract in practicallyunaltered condition ”the council holds that stanolind liquid paraffin is a drug, and that, therefore, its direct advertising to the public is in contraventionof the council rules constipation should be treated by dietaryand hygienic means evacuants are only temporary measures liquidpetrolatum is medicinal.

4 three tabletsof custom writing services such secretogen in 15 c c of 70 per cent alcohol. 5 15 c c elixirsecretogen tracing b. Reading from left to right, the four intravenousinjections are. 1 5 c c secretin made fresh from dog duodenalmucosa. 2 three tablets of duodenin digested in 15 c c 0 4 per cent hydrochloric acid and neutralized. 3 three tablets of duodenin boiledin 15 c c 0 4 per cent hydrochloric acid and neutralized.

Outwardly it clears the sight, takes awayinflammations, scabs, itch, the custom writing services such shingles, and all spreading sores, and is as wholeessay an herb as can grow about any an house tragus, dioscorides polium, &c polley, or pellamountain. All the sorts are hot inthe second degree, and dry in the third. Helps dropsies, the yellowjaundice, infirmities of the spleen, and provokes urine dioscorides polygonum knotgrass polytricum maidenhair portulaca purslain. Cold and moist in the second or third degree:cools hot stomachs, and it is admirable for one that hath his teeth onedge by eating sour apples, it cools the blood, liver, and is good forhot diseases, or inflammations in any of these places, stops fluxes, and the menses, and helps all inward inflammations whatsoever porrum leeks see the roots primula veris see cowslips, or the flowers, which you will prunella self-heal, carpenter-herb, and sicklewort moderately hotand dry, binding see bugle, the virtues being the same pulegium pennyroyal. Hot and dry in the third degree. Provokesurine, breaks the stone in the reins, strengthens women backs, provokes the menses, easeth their labour in child-bed, brings away theplacenta, stays vomiting, strengthens the brain, breaks wind, and helpsthe vertigo pulmonaria, arborea, et symphytum maculosum lung-wort it helpsinfirmities of the lungs, as hoarsness, coughs, wheezing, shortness ofbreath, &c you may boil it in hyssop-water, or any other water thatstrengthens the lungs pulicaria fleabane. Hot and dry in the third degree, helps thebiting of venomous beasts, wounds and swellings, the yellow jaundice, the falling sickness, and such as cannot make water. Being burnt, the smoak of it kills all the gnats and fleas in the chamber. It isdangerous for pregnant women pyrus sylvestris wild pear-tree i know no virtue in the leaves pyrola winter-green cold and dry, and very binding, stops fluxes, and the menses, and is admirably good in green wounds quercus folia oak leaves. Are much of the nature of the former, staythe fluor albus see the bark ranunculus hath got a sort of english names. Crowfoot, king-kob, gold-cups, gold-knobs, butter-flowers, &c they are of a notable hotquality, unfit to be taken inwardly. If you bruise the roots and applythem to a plague-sore, they are notable things to draw the venom tothem raparum folia if they do mean turnip leaves, when they are youngand tender, they are held to provoke urine rosmarirum rosemary, hot and dry in the second degree, binding, stops fluxes, helps stuffings in the head, the yellow jaundice, helpsthe memory, expels wind see the flowers serapio, dioscorides rosa solis see the water rosa alba, rubra, damascena white, red, and damask roses rumex dock.

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The absence of a name from suchcopy or the want of such certificate is prima facie evidence thatsuch person is not registered if a name does not appear on the copy, acertified copy, under the hand of the registrar of the council, of theentry of a name on the register is evidence of registration s 8 entrance upon study - a person beginning or entering on the studyof physic, surgery, or midwifery, for the purpose of qualifying topractise in the province, must have obtained from the custom writing services such council acertificate that he has satisfactorily passed a matriculation orpreliminary examination in the subjects enumerated in the act, unlesshe has passed a matriculation examination for the medical course inarts and science at essay college in great britain, ireland, canada, theunited states of america, or the continent of europe 10 the act prescribes formalities for admission to such preliminaryexamination 10 qualification - subject to the exceptions hereinafter, no personcan lawfully practise physic, surgery, or midwifery unless he beregistered, or unless he shall have received from the council a licenseto practise 11 no person is entitled to registration or license unless he shallsatisfy the council that he has passed a matriculation or preliminaryexamination. That after passing such examination he has followed hisstudies for not less than four years, one of which may be under thedirection of one or more general practitioners duly licensed. Thatduring such four years he has attended at essay university, college, or incorporated school of medicine in good standing, courses oflectures amounting together to not less than twelve months on generalanatomy, on practical anatomy, on surgery, on practice of medicine, on midwifery, on chemistry, on materia medica and pharmacy, and onthe institutes of medicine or physic, and one three-months’ courseof medical jurisprudence. That he has attended the general practiceof an hospital in which are not less than fifty beds under the chargeof not less than two physicians or surgeons, for not less than oneyear or two periods of not less than six months each. That he hasalso attended two three-months’ courses or one six-months’ course ofclinical medicine, the same of clinical surgery. That he has, after anexamination in the subjects of the course, obtained a degree or diplomafrom such university, college, or incorporated medical school if suchinstitution require a four-years’ course for its diploma, or for thewant of such degree or diploma that he has satisfactorily passed anexamination in the various branches hereinbefore specified before theexaminers appointed by the council. That he is not less than twenty-oneyears of age. That he has paid to the registrar of the council a feeof ten dollars the council has power, subject to the approval ofthe governor in council, to make alterations as may be required inthe foregoing curriculum if any person apply for registration as apractitioner of any system of medicine, the registered practitioners ofthat system have the right to appoint an examiner or examiners on thesubjects peculiar to that system, viz , materia medica, pharmacy, andtherapeutics, and if they neglect so to do the council has the power toappoint such examiner or examiners 12 the last preceding section does not apply to persons in actual practiceentitled to register under sec 38 any person producing to the councilconclusive evidence that he has passed a matriculation or a preliminaryexamination, as required by this act for persons beginning medicalstudies in new brunswick, that he has before graduating or taking adiploma studied at least four years as provided in sec 12, or pursuedwhat the council deem an equivalent course of study and has passed afinal examination in the subjects of such course, or, for the want ofsuch requirement, shall have fulfilled such conditions as the councilmay determine, and shall pay a fee of ten dollars, shall be entitled toregistration and to receive a license to practise 13 the act makes special provision for residents of the province who beganstudy before january 1st, 1881 14, as amended 1882, c 30, s 1 duties of council - the council is empowered and required to regulatethe study of medicine, surgery, and midwifery, with regard topreliminary qualifications, course of study, final examination, and theevidence to be produced before the council. To appoint a registrationcommittee. To examine all degrees, diplomas, licenses, and othercredentials presented or given in evidence under the act to enable theowner to practise in new brunswick, and to oblige the owner to atteston oath or affirmation that he is the person whose name is mentionedtherein, and that he became possessed thereof properly and honestly;to cause every member of the profession practising in new brunswick toregister his name, age, place of residence, place of nativity, dateof license or diploma, and the place where he obtained it.