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Critical Analysis Essay Outline


This herb wormwood being laid among cloaths, will make a mothscorn to meddle with the cloaths, as much as a lion scorns to meddlewith a mouse, or an eagle with a fly you say mars is angry, and it istrue enough he is angry with thesis countrymen, for being such fools tobe led by the noses by the college of physicians, as they lead bears toparis garden melancholy men cannot endure to be wronged in point ofgood fame, and that doth sorely trouble old saturn, because they callhim the greatest infortunate. In the body of man he rules the spleen, and that makes covetous man so splenetic the poor old man lies cryingout of his left side father saturn angry, mars comes to him. Come, brother, i confess thou art evil spoken of, and so am i.

Which, in turn, means early therapeutic effects and little or no fear of toxic accumulation ”that removal of colloids and resins materially affects the toleranceof these drugs is improbable to claim that because of their removal, there need be “little or no fear of toxic accumulation” is utterlywithout warrant the claim that one preparation containing digitalisis less likely to produce cumulative effect than any other digitalispreparation is contradicted by a mass of evidence it is claimed that hydropsin affects “favorably all forms of dropsyor edema that are at all amenable to medical treatment ” there can beno question but that squill and digitalis, or, better, either singly, used in suitable paper, may relieve dropsical effusions. But to claimthat such a complex mixture as hydropsin can favorably affect allforms of dropsy that are amenable to medical treatment is on its faceunwarranted the claim is made that. “by reason of its unusual potency and relative harmlessness, hydropsin may be employed to great advantage in all paper where it is desirable to increase the volume of urine without injury to the renal structures ”on the basis of the claimed composition, the action of hydropsinmust be essentially that of digitalis or of digitalis and squill consequently, if it possesses “unusual potency, ” it cannot possess“relative harmlessness, ” and vice versa neither digitalis norsquill should be employed “in all paper” of nephritis, even if it is“desirable to increase the volume of urine ”the composition claimed for hydropsin brands it as an irrationalmixture in which potent drugs are combined with, and more or lesscovered up by, others that are obsolete and inefficient the name, instead of indicating its composition, suggests diseases in which itmay be thoughtlessly and indiscriminately used the claim that thedanger of toxic or cumulative action has been removed, if accepted byphysicians, tends to uncritical use with possible disastrous results hydropsin is ineligible for new and nonofficial remedies because ofconflict with rules 1, 2, 6, 8 and 10 -- from the journal a m a , jan 8, 1916 digitalysatum report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary digitalysatum is sold in the united states by ernst bischoff company, inc , new york the firm claims that it is a dialysate prepared fromthe juice of freshly gathered digitalis, containing all the activeprinciples, and representing the fresh plant weight for weight it issaid to be standardized physiologically and to contain 12 per cent alcohol sterisol-digitalysatum, intended for injection, appearsto be the “dialysate” without alcohol, diluted with equal writings ofphysiologic sodium chlorid solution the council essay years ago foundboth products ineligible for new and nonofficial remedies becauseof unwarranted therapeutic claims the preparations are still beingadvertised to physicians under claims which imply superiority to allother digitalis preparations for instance. “digitalysatum is the diuretic par excellence in cardiac insufficiency ” “digitalysatum as a diuretic and cardiac stimulant is in a class by itself, being quick of action, uniform in strength, and well tolerated ” “digitalysatum differs from other forms of digitalis in these respects. Digitalysatum is free from fat, resins and colloids, and is therefore well-borne by sensitive patients-- the young and the feeble-- and is quickly absorbed and eliminated ”the council has elsewhere28 expressed the conviction that tinctureof digitalis produces the full therapeutic effects of digitalis. That, when properly made, the tincture is as stable as any liquid preparationof digitalis now available, and that attempts to enhance the reputationof proprietary products by exaggerating the disadvantages of theofficial preparation are to be deplored no adequate evidence isoffered of the claimed superiority of action of digitalysatum 28 report on proprietary digitalis preparations, j a m a , dec 4, 1915, p 2024 by implication, the claim is made that digitalysatum is superior toother digitalis preparations in respect to toxicity. “free from fat, resins and colloidals, it is always well borne and is quickly absorbed and eliminated no case of toxic accumulation faulty elimination has ever been reported ”that digitalysatum is free from the dangers of toxic cumulation ishighly improbable. In fact, it is inconsistent with the statementthat the preparation contains all the constituents found in the freshplant even if instances of cumulative action have not been reportedthis does not prove that such cumulative action does not occur thetincture of digitalis has the systemic side-effects of digitalis in nogreater degree than the various proprietary preparations attempts tocreate the impression that digitalysatum possesses all the virtues ofdigitalis without its chief disadvantage are to be condemned as likelyto lead to incautious use of the preparation these exaggerated claims are in the main made indirectly, but they arenone the less inimical to sound therapy the council therefore declareddigitalysatum ineligible for new and nonofficial remedies and votedthat this report be published -- from the journal a m a , jan 8, 1916 so-called secretin preparations report of the council on pharmacy and chemistrythe council authorized the following report for publication, and votedto endorse the work of professor carlson discussed therein w a puckner, secretary the council has not accepted for inclusion in new and nonofficialremedies any preparations said to contain secretin or prosecretin astheir active ingredient a report giving the reasons for the rejectionof one the first of the so-called secretin preparations marketed waspublished early last year;29 an article on secretin, based on workundertaken at the request of the council on pharmacy and chemistry, isnow published 3029 secretogen, j a m a , may 1, 1915, p 1518 30 carlson, a j. Lebensohn, j e , and pearlmann, s j. Hassecretin a therapeutic value?. j a m a 66:178 jan 15 1916 lest the appearance of this detailed study of secretin, after therejection of so-called secretin preparations, should be interpreted as manufacturers whose products have been rejected have endeavored tointerpret such action as a case of first condemning a preparation andthen getting the facts, the council methods, and their applicationin this case, may be briefly stated the council maintains that, when a manufacturer places a product on the market, the burden ofproof is on that manufacturer to show that the properties of hisproduct are in accordance with his claims for it as stated in theintroduction to n n r , “it is manifestly impossible for thecouncil to investigate the composition of every complex pharmaceuticalmixture, or to check thoroughly every therapeutic claim. It can giveonly an unbiased judgment on the available evidence ” acting on thisprinciple, the council examined the claims made for secretogen, analleged secretin product manufactured by the g w carnrick company the conclusion was that these claims were in absolute conflict with theavailable evidence as to the action of secretin it is not necessary to review this subject again it will suffice tostate that the claims made for secretogen rest on two fundamentalpropositions. 1 that deficiency of secretin or, rather, ofprosecretin in the intestinal mucosa is a factor in gastro-intestinaldiseases.

According to matthiolus, helps critical analysis essay outline ruptures. You maytake half a dram at a time ostrutij masterwort, given once before under the name ofimperitoria but i have essaything else to do than to write one thingtwice as they did pastinatæ, sativæ, and silvestris garden and wild parsnips theyare of a temperate quality, inclining essaything to heat. The gardenparsnips provoke lust, and nourish as much and more too, than any rootordinarily eaten.

“by reason of its unusual potency and relative harmlessness, hydropsin may be employed to great advantage in all paper where it is desirable to increase the volume of urine without injury to the renal structures ”on the basis of the claimed composition, the action of hydropsinmust be essentially that of digitalis or of digitalis and squill consequently, if it possesses “unusual potency, ” it cannot possess“relative harmlessness, ” and vice versa neither digitalis norsquill should be employed “in all paper” of nephritis, even if it is“desirable to increase the volume of urine ”the composition claimed for hydropsin brands it as an irrationalmixture in which potent drugs are combined with, and more or lesscovered up by, others that are obsolete and inefficient the name, instead of indicating its composition, suggests diseases in which itmay be thoughtlessly and indiscriminately used the claim that thedanger of toxic or cumulative action has been removed, if accepted byphysicians, tends to uncritical use with possible disastrous results hydropsin is ineligible for new and nonofficial remedies because ofconflict with rules 1, 2, 6, 8 and 10 -- from the journal a m a , jan 8, 1916 digitalysatum report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary digitalysatum is sold in the united states by ernst bischoff company, inc , new york the firm claims that it is a dialysate prepared fromthe juice of freshly gathered digitalis, containing all the activeprinciples, and representing the fresh plant weight for weight it issaid to be standardized physiologically and to contain 12 per cent alcohol sterisol-digitalysatum, intended for injection, appearsto be the “dialysate” without alcohol, diluted with equal writings ofphysiologic sodium chlorid solution the council essay years ago foundboth products ineligible for new and nonofficial remedies becauseof unwarranted therapeutic claims the preparations are still beingadvertised to physicians under claims which imply superiority to allother digitalis preparations for instance. “digitalysatum is the diuretic par excellence in cardiac insufficiency ” “digitalysatum as a diuretic and cardiac stimulant is in a class by itself, being quick of action, uniform in strength, and well tolerated ” “digitalysatum differs from other forms of digitalis in these respects. Digitalysatum is free from fat, resins and colloids, and is therefore well-borne by sensitive patients-- the young and the feeble-- and is quickly absorbed and eliminated ”the council has elsewhere28 expressed the conviction that tinctureof digitalis produces the full therapeutic effects of digitalis. That, when properly made, the tincture is as stable as any liquid preparationof digitalis now available, and that attempts to enhance the reputationof proprietary products by exaggerating the disadvantages of theofficial preparation are to be deplored no adequate evidence isoffered of the claimed superiority of action of digitalysatum 28 report on proprietary digitalis preparations, j a m a , dec 4, 1915, p 2024 by implication, the claim is made that digitalysatum is superior toother digitalis preparations in respect to toxicity. “free from fat, resins and colloidals, it is always well borne and is quickly absorbed and eliminated no case of toxic accumulation faulty elimination has ever been reported ”that digitalysatum is free from the dangers of toxic cumulation ishighly improbable. In fact, it is inconsistent with the statementthat the preparation contains all the constituents found in the freshplant even if instances of cumulative action have not been reportedthis does not prove that such cumulative action does not occur thetincture of digitalis has the systemic side-effects of digitalis in nogreater degree than the various proprietary preparations attempts tocreate the impression that digitalysatum possesses all the virtues ofdigitalis without its chief disadvantage are to be condemned as likelyto lead to incautious use of the preparation these exaggerated claims are in the main made indirectly, but they arenone the less inimical to sound therapy the council therefore declareddigitalysatum ineligible for new and nonofficial remedies and votedthat this report be published -- from the journal a m a , jan 8, 1916 so-called secretin preparations report of the council on pharmacy and chemistrythe council authorized the following report for publication, and votedto endorse the work of professor carlson discussed therein w a puckner, secretary the council has not accepted for inclusion in new and nonofficialremedies any preparations said to contain secretin or prosecretin astheir active ingredient a report giving the reasons for the rejectionof one the first of the so-called secretin preparations marketed waspublished early last year;29 an article on secretin, based on workundertaken at the request of the council on pharmacy and chemistry, isnow published 3029 secretogen, j a m a , may 1, 1915, p 1518 30 carlson, a j. Lebensohn, j e , and pearlmann, s j. Hassecretin a therapeutic value?.

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In the third report, fifty-six of ninety paper were reported cured critical analysis essay outline. In this larger series ofpaper the author neglects to state the method of administration thefirm quotes but one paper which is a very uncritical report in regardto pellagra it seems to the council that the evidence of value of sodium arsanilatein these conditions which are now treated by more rational methods istoo slight to justify the emphasis laid on it by the firm, especiallyas sodium arsanilate is admittedly a dangerous agent, several paper ofblindness having been reported from its use for these reasons it was voted to omit soamin from new and nonofficialremedies -- from reports of council on pharmacy and chemistry, 1919, p 89 essay mixed vaccines not admitted to n n r report of the council on pharmacy and chemistrythe council has authorized publication of the following report w a puckner, secretary the consideration of the following “mixed” vaccines was requested byf i lackenbach, san francisco. Special bacterial vaccine no 2 staph-strep bacterin containing killed staphylococcus albus, staphylococcus aureus and streptococcus special bacterial vaccine no 3 pneumo-staph-strep bacterin containing killed staphylococcus albus, staphylococcus aureus, streptococcus and pneumococcus special bacterial vaccine no 4 pneumo-staph-strep-coli bacterin containing killed staphylococcus albus, staphylococcus aureus, staphylococcus citreus, bacillus coli, streptococcus and pneumococcus special bacterial vaccine no 5 influenza combined bacterin containing killed staphylococcus albus, staphylococcus aureus, bacillus friedländer, bacillus influenzae, micrococcus catarrhalis, streptococcus and pneumococcus special bacterial vaccine no 11 pneumo-strep bacterin containing killed streptococcus and pneumococcus special bacterial vaccine no 15 combined whooping cough bacterin containing killed bacillus pertussis, staphylococcus albus, staphylococcus aureus, micrococcus catarrhalis, bacillus influenzae, streptococcus and pneumococcus special bacterial vaccine no 16 mixed gonococcus bacterin containing killed gonococcus, staphylococcus albus, staphylococcus aureus, bacillus coli, diphtheroid bacillus, streptococcus and pneumococcus mr lackenbach states that these bacterial mixtures were preparedfor him by e r squibb & sons their sale in interstate commerce ispermitted under the license granted to the latter firm by the u s treasury dewritingment however, no evidence of any kind was presentedto the council proving the therapeutic efficacy of the several mixedvaccines as a mixture of two or more kinds of organisms is acceptedfor new and nonofficial remedies only if there is satisfactory evidencethat its therapeutic use is rational, the council declared the severalvaccine mixtures ineligible for new and nonofficial remedies rule10 -- from reports of council on pharmacy and chemistry, 1919, p 90 somnoform report of the council on pharmacy and chemistrythe council examined the available evidence for somnoform, sold bystratford-cookson company, successors to e de trey and sons, and foundthe preparation inadmissible to new and nonofficial remedies thecouncil authorized publication of the report which appears below w a puckner, secretary somnoform is sold in the united states by stratford-cookson company, successors to e de trey and sons according to the label on a packageof somnoform sent the council “this mixture contains chloride of ethyl, 83 per cent. Chloride of methyl, 16 per cent. Bromide of ethyl, 1 per cent ”although somnoform has been on the market for a long time, thepublished reports present no proof that it is superior to ethylchlorid used alone moreover, the published reports and statistics donot necessarily apply to the somnoform now sold for the reason thatmixtures of varying composition have been sold as somnoform in thepast thus, when somnoform was considered by the council in 1909, itwas claimed to be composed of chloride of ethyl, 60 per cent. Chlorideof methyl, 35 per cent , and bromide of ethyl, 5 per cent federalchemists found, however, that it contained no bromide of ethyl noticeof judgment no 571 it is a question, therefore, whether a givenreport applies to a mixture containing 5 per cent bromide of ethyl, 1per cent of this substance, or none at all the present advertising booklet for somnoform does not presentacceptable evidence of the therapeutic value of the preparation an ignorance concerning the elementary facts of physiology andpharmacology is evident in the second sentence. When having stated that“somnoform is the result of several years of study and investigation bydr george rolland, dean of the bordeau dental school, ” the pamphletcontinues. “he sought an anesthetic which would enter, dwell in, andleave the body in the same manner that oxygen does ”the claim as to the value of the 1 per cent of ethyl bromide in themixture is highly improbable. Certainly no evidence in support of theclaimed value of this constituent is available to the referee no evidence is submitted which proves the claim of superiority ofsomnoform over similar preparations, asserted in the following. “the peculiar manner in which the elements are combined is what makes somnoform at once so efficient and so safe ”the council declared somnoform inadmissible to new and nonofficialremedies because, in the absence of acceptable evidence showing itsexceptional safety and value, the claims are unwarranted rule 6, andbecause the name of the mixture is not descriptive of its composition rule 8 -- from reports of council on pharmacy and chemistry, 1919, p 90 tablets formothalates report of the council on pharmacy and chemistrythe council has authorized publication of the following report whichdeclares tablets formothalates tailby-nason company, boston, mass ineligible for new and nonofficial remedies w a puckner, secretary tablets formothalates are sold by tailby-nason company, boston, mass on the label a formula is given.