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If not, i hold sugarto be better than honey 5 it is kept in pots, and may be kept a year and longer 6 it is excellent for roughness of the wind-pipe, inflammations andulcers of cheap online term paper writers for college students the lungs, difficulty of breathing, asthmas, coughs, anddistillation of humours chapter x of ointments 1 various are the ways of making ointments, which authors have leftto posterity, which i shall omit, and quote one which is easiest tobe made, and therefore most beneficial to people that are ignorant inphysic, for whose sake i write this it is thus done:bruise those herbs, flowers, or roots, you will make an ointment of, and to two handfuls of your bruised herbs add a pound of hog greasedried, or cleansed from the skins, beat them very well together in astone mortar with a wooden pestle, then put it into a stone pot, theherb and grease i mean, not the mortar, cover it with a paper and setit either in the sun, or essay other warm place. Three, four, or fivedays, that it may melt. Then take it out and boil it a little. Thenwhilst it is hot, strain it out, pressing it out very hard in a press:to this grease add as thesis more herbs bruised as before.

Forwhich likewise the black seed beaten to powder, and given in wine, is also available the black seed also taken before bed-time, and inthe morning, is very effectual for such as in their sleep cheap online term paper writers for college students are troubledwith the disease called ephialtes, or incubus, but we do commonly callit the night-mare. A disease which melancholy persons are subjectunto. It is also good against melancholy dreams the distilled wateror syrup made of the flowers, works the same effects that the rootand seed do, although more weakly the female is often used for thepurpose aforesaid, by reason the male is so scarce a plant, that it ispossessed by few, and those great lovers of rarities in this kind pepperwort, or dittander descript our common pepperwort sends forth essaywhat long and broadleaves, of a light blueish green colour, finely dented about the edges, and pointed at the ends, standing upon round hard stalks, three orfour feet high, spreading thesis branches on all sides, and having thesissmall white flowers at the tops of them, after which follow small seedsin small heads the root is slender, running much under ground, andshooting up again in thesis places, and both leaves and roots are veryhot and sharp of taste, like pepper, for which cause it took the name place it grows naturally in thesis places of this land, as at clarein essex.

And that my product is capable of producing a new lease of life in those whose functions have been reduced to a minimum ”how long edgar has been featuring his “serum” for “sex stimulation”it is difficult to determine, but during the last year the cheap online term paper writers for college students newspapershave carried sporadic reports of alleged remarkable results producedby “dr thomas webster edgar of 766 west end ave , new york, ” throughthe transplantation of the “interstitial gland” taken from “a specialspecies of orangoutang ” a layman who wrote edgar essay months agoregarding this “gland implantation” received a letter from edgarsecretary stating that the treatment “has been most successful inall paper” and assuring him that “the experimental stage had beenpassed, and the operation is advised in all paper presenting symptomsof presenility or age ” a week later the same man received a letterwritten by edgar himself in which he reiterated the claim that allof the operations had been successful edgar added that he was nowtreating all paper “by operation instead of the serum, ” and that“the fee for operation is $500, inclusive of the sanitarium, ” thepatients remaining in the “sanitarium” “for from two to three days ”a month or two later the prospective patient received another lettersigned, “thomas webster edgar, m d , ” assuring him that “the effect ispermanent, and does not wear off no ill effects can possibly result ”commencing, oct 1, 1921, a series of sensational articles appearedregarding one of edgar alleged monkey gland implantations performedon an individual described as “one time lawyer and then a writer ”these articles purport to be written writingly by one of the newspaperstaff, writingly by the man undergoing the “operation” and at leastone by thomas webster edgar the material is played up in the styletypical of yellow journalism in addition to repeated pictures of theindividual who is being operated on, there also are given pictures ofthomas webster edgar and one of his “ring-tailed monkeys ” doubtlessthe “story” has sold thesis newspapers its sensational character, theelement of mystery and above all its sex slant will appeal to thatlarge class of newspaper readers that hunger for stuff of this sort doubtless, too, it has proved a large advertising asset for thomaswebster edgar the statement that appears in the series to the effect that edgar “is amember of the county medical society of new york” is incorrect edgaris not a member the further newspaper claim that edgar is “an authority on glandulartransplantation” should also be accepted with reservations “authorities” are created with ease in the pages of newspapers edgarmay possibly be termed an authority in a newspaper or, shall we say, pickwickian sense -- from the journal a m a , oct 15, 1921 the journal receives a letter denouncing “medical clerks” and “biased sceptres”the journal recently published in this dewritingment essay inquiriesregarding thomas webster edgar, m d , of new york city, relative toessay alleged serums that dr edgar had developed for diabetes and sexstimulation, respectively, and relative also to the newspaper publicitygiven dr edgar in connection with the alleged transplantation ofglands from “ring-tailed monkeys ”we are in receipt of a letter signed, “thomas webster edgar, m d , ” andreading as follows it is given verbatim et literatim. “gentlemen:-- i have read with great interest your editorial regarding the publicity given my work in metabolism, and gland implantation “your pseudo, expose, and distinctly libelous insinuations are unjust, and they lead me to believe that you are going to be called to account at a very early date “my profession is the practice of medicine, and the policy of my practice is not controlled by the editorial dewritingment of the journal i am progressive, and a firm believer that legitiment medicine and surgery can not be practiced if the physician be governed by a set of medical clerks, who disdainfully boast that they control, and govern the healing art through out the breadth of the land, with a sceptre that is biased and steeped in the unadulterated commercialism of a certain medical clique “aside from the fact that i am an associate editor on a medical publication, it is disgraceful, as well as unjust that you have written such an editorial with out first investigating the therapeutic value of my serum, and implantation operation “the psychology of your editorial, only reflects on your editorial dewritingment, and will tend to belittle essay of the greatest surgeons in the country “it may be to your advantage to know, that this very afternoon, i was on the program with the following men “dr lewis gregory cole-- new york “dr charles h mayo-- rochester, minn “dr john b deaver-- philadelphia “dr charles peck-- new york “my paper was entitled-- senility, its etiology and treatment by gland implantation i am sure the above mentioned gentlemen are thoroughly ashamed of your actions in the matter, as well as thoroughly disgusted with the baby like attitude you have displayed you have no sense of fair play, and if it is with in my power to undue the wrong which you have wrought me, i shall endeavor to vindicate myself in the eyes of the clear thinking members of the profession “i sincerely trust you will publish this communication, in order that my brethren shall understand and appreciate that your thrust has not gone unnoticed “it is my hope that the various medical societies through out the country, will call upon me to read a paper on my work, so that i may be able to offer substantial evidence to the fact that you have done me an injustice “very truly yours, twe/ael signed “thomas webster edgar, m d ”dr edgar statement that he had been on the program with drs cole, mayo, deaver and peck was sufficiently startling to prompt furtherinvestigation it was found that the program in question was that ofthe annual meeting of the new york and new england association ofrailway surgeons it was further found that edgar name did appear onessay of the printed programs but not on others it was rather naturallyassumed that the name had been put on the program before the officersof this organization had seen the crude publicity to which the journalrecently called attention it was found, however, that after severalhundred programs had been printed about 150 more were needed and “inthe meantime, dr edgar had come into the limelight” in his ring-tailedmonkey gland transplantation rôle and “was invited to read a paper onthe subject ” while he accepted this invitation the secretary of theorganization tells us that edgar did not read his paper but, when thepaper was called, declined, saying it was time for him to be in hisoffice!. As for the rest of dr edgar communication, the journalappreciates that courtesy is due “an associate editor on a medicalpublication”-- referring doubtless to the western medical times dr edgar pronouncement that “legitimate medicine and surgery cannot be practiced if the physician be governed by a set of medicalclerks” seems reasonable-- if cryptic but it is when he charges thatthese “clerks” govern the healing art “with a sceptre that is biasedand steeped in the unadulterated commercialism of a certain medicalclique, ” that he really shines whatever opinion one may hold of dr edgar ability to compound serums, surely no one can question hisskill as a mixer of metaphors his reference to “sceptres” deservesto be embalmed in every textbook on rhetoric with the classic of thehibernian statesman who passionately declared. “i smell a rat!. i seeit floating in the air!. but, mark you, sir, i shall nip it in thebud!. ”-- from the journal a m a , dec 3, 1921 glycerophosphatesphysicians who prescribe on definite principles must often be puzzledby the number and variety of glycerophosphates on the market allavailable evidence indicates that, as sources of phosphorus to theanimal organism, the glycerophosphates possess no advantages over theordinary inorganic phosphates 290 the glycerophosphates are splitup in the intestine, and liberate inorganic phosphates in this formthey are absorbed and utilized, if they are utilized at all there isno evidence that glycerophosphates have any pharmacologic action towarrant the belief that they are of use as therapeutic agents thetheory that organic phosphorus compounds are more readily assimilablethan inorganic compounds and hence a better means of introducingphosphorus into the system is still kept alive in the promotion ofcertain proprietary mixtures, in spite of the scientific evidence thatthe organism can assimilate phosphorus quite as readily from inorganicas from organic phosphorus compounds 291 the glycerophosphates willcontinue to be manufactured until physicians refuse to prescribe them a chemist in the “research laboratory” of a well known manufacturingfirm has recently given a rather interesting reason for the use ofglycerophosphates-- from the manufacturers’ point of view he is quotedas saying. “on account of the instability of phosphorus in elixir ofphosphorus, nux vomica and damiana we have quite recently replacedthe phosphorus by glycerophosphates such a preparation is apparentlyequally as effective, for we continue to have a great demand for it ”this is doubtless a sufficient reason for the substitution from themanufacturers’ point of view. But how about the patient, who, afterall, is the one to be considered?. is it not a matter of considerableimportance to the patient whether he receives phosphorus, one ofthe most powerful drugs known, or the inert glycerophosphates?. thechemist statement seems to imply that it is not it may be ofinterest to recall that a member of the firm whose chemist givesthis “reason” for the use of glycerophosphates, in a recent address, was rather severe in his condemnation of institutions of learning, hospitals, etc , for their lack of cooperation with manufacturers. Hesaid that “they should welcome an opportunity to let any manufacturertry out or test his products in their clinics, laboratories, etc ”a test as to whether there is a difference between the action ofglycerophosphates and ordinary poisonous yellow phosphorus, especiallywhen the former are mixed with extracts of nux vomica and damiana, would not be likely to appeal to thesis hospitals and laboratories asa very promising field of research at this day since, as has beenstated, the scientific evidence at present available does not furnishany warrant for the therapeutic use of glycerophosphates -- editorialfrom the journal a m a , april 15, 1916 290 organic phosphoruscompounds, editorial, j a m a 40. 1958 june 21 1913 marshall, e k. The therapeutic value of organic phosphorus compounds, j a m a 44.

These are a solubility in alcohol, and b thetest for uncombined tribromphenol {”}when the two recent samples of bismuth tribromphenate-merck and twosamples of xeroform-heyden were examined according to the new monographthe results given in table 8 were obtained table 8 -- examination of tribromphenate and xeroform 1 bismuth weight of per cent weight bi₂o₃ of brand and date received taken, obtained, bismuth, gm gm gm xeroform-heyden from mfr july, 1918 0 6754 0 3565 47 2 xeroform-heyden open market july, 1918 0 8259 0 6156 66 7 bismuth tribromphenate-merck nov , 1918 0 4882 0 2512 46 1 bismuth tribromphenate-merck dec , 1918 0 8869 0 4495 45 5 2 uncombined tribromphenol no c c per cent weight of tenth- of free brand and date received taken, normal naoh tribrom- gm consumed, phenol c c xeroform-heyden from mfr july, 1918 1 7 4 24 5 xeroform-heyden open market july, 1918 1 0 7 2 3 bismuth tribromphenate-merck nov , 1918 1 5 7 18 8 bismuth tribromphenate-merck dec , 1918 1 5 16 5in view of the laboratory report the referee of the council onpharmacy and chemistry in charge of bismuth tribromphenate recommendedthat the acceptance of xeroform-heyden and bismuth tribromphenate-merckbe withdrawn, but that this should be without prejudice to theirreinstatement when satisfactory products are again offered for sale the council adopted the recommendation of the referee and accordinglyxeroform-heyden and bismuth tribromphenate-merck are omitted from newand nonofficial remedies, 1919 when the laboratory findings with regard to xeroform-heyden and theaction of the council deleting the article from new and nonofficialremedies was reported to the heyden chemical works, the firm expressedregret that efforts to produce a product equal to that formerlyobtained from gerthesis had so far not been successful and announcedthat it had decided to withdraw xeroform-heyden from the market forthe present when merck and co was advised in regard to the reportof the laboratory and council action, this firm questioned thefeasibility of producing a product meeting the council standards andsuggested that the test for free tribromphenol be revised to permitas much as 15 per cent of this constituent when merck and co wasreminded that its product submitted in 1915 essentially complied withthe adopted standards an old sample of xeroform-heyden was also foundto comply and that the estimate of the therapeutic value of bismuthtribromphenate is based on a product essentially devoid of freetribromphenol, the firm replied:“as stated in our letter of the 12th inst , we do not wish to marketthe chemical unless it meets all legitimate requirements of thephysicians that use it if, therefore, your standard proves to be goodand it is commercially possible to make supplies conforming to it, weshall do so we shall discontinue the article unless it is of suitablequality ”-- from reports a m a chemical laboratory, 1918, p 93 the standardization of procain and examination of the market supplyprocain, which chemically is the mono-hydrochlorid ofpara-amino-benzoyldiethyl-amino-ethanol, is the nonproprietary nameselected by the federal trade commission as the official designationfor the drug previously known under the proprietary name “novocaine ”before the war procain was obtainable in this country only throughthe farbwerke hoechst co , the american representative of the germanestablishment, farbwerke, vorm, meister, lucius and bruening, underthe name “novocaine ” this monopoly on “novocaine” was exercised byvirtue of united states patent no 812554, which was issued to alfredeinhorn, munich, gerthesis, assignor to farbwerke, vorm, meister, luciusand bruening, hoechst a m , in 1906 with the outbreak of hostilities, congress passed the trading with the enemy act, and under this, thefederal trade commission took charge of the novocain patent with aview of securing the production of this product in the united states to ensure an adequate supply of the drug, the federal trade commissionon recommendation of the committee on synthetic drugs of the nationalresearch council, in addition to issuing a license to the farbwerkehoechst company which license was later transferred to the h a metzlaboratories granted authority to the abbott laboratories and therector chemical company to manufacture it under the u s patent afterspecimens submitted by these firms had been found satisfactory in theassociation laboratory and at the cornell pharmacologic laboratory when the first specimen of american made procain was sent to theamerican medical association chemical laboratory it was necessary towork out adequate standards the standards were formulated on the basisof the novocain monograph in the german pharmacopeia, 1910, ed 5, p 363, remedia “hoechst, ” p 242, and new and nonofficial remedies, 1918, p 32, and the work carried out in this laboratory the following description has been adopted for new and nonofficialremedies, 1919, and all specimens of procain were subjected to thesetests:procain occurs in small colorless and odorless crystals, or acrystalline powder which if placed on the tongue produces a transientsense of numbness it melts at 153-155 c 212212 u s patent number 812, 554-- the novocain patent-- declaresthat the salt melts at 156 c evidently based on this, the germanpharmacopoeia remedia “hoechst” and past editions of new andnonofficial remedies give this melting point two specimens of germanmade novocain obtained from our files, stated to be manufactured byfarbwerke-hoechst vorm meister, lucius and bruening, hoechst a m were found to melt, respectively, between 154 and 155 c and between153 5 and 154 5 c when the melting point was determined according tothe directions of the u s pharmacopoeia, 9th revision the variousspecimens examined at that time melted between 153 and 155 c and itwas decided to permit this range one gm of procain is soluble in 0 7 c c of water and in 20 c c ofalcohol u s p 95 per cent at 20 c from the aqueous solution, which is neutral, alkali hydroxids and carbonates precipitate thefree base in the form of a colorless oil, which soon congeals to acrystalline mass, but solutions of sodium bicarbonate are miscible withsolutions of procain without producing precipitations or turbidity dissolve 1 gm of procain in water separate portions of the solutionyield a white precipitate with potassium mercuric iodid solution, a white precipitate with mercuric chlorid test solution, a brownprecipitate with iodin test solution and a yellow precipitate withpicric acid test solution acidify a portion with dilute nitric acid a white curdy precipitate is thrown down on the addition of silvernitrate test solution dissolve about 0 1 gm of procain in 5 c c of water, add 2 drops ofdilute hydrochloric acid and 2 drops of sodium nitrite solution 10 percent and mix with a solution of 0 2 gm of betanaphthol in 10 c c ofsodium hydroxid solution 10 per cent a scarlet red precipitate isthrown down to a solution of about 0 1 gm of procain in 5 c c of water add 3drops of dilute sulphuric acid and mix with 5 drops of potassiumpermanganate test solution the violet color of the latter disappearsimmediately distinction from cocain dissolve about 0 1 gm procain in 1 c c sulphuric acid u s p thesolution is colorless organic impurities dissolve 0 1 gm of the salt in 10 c c of water and saturate withhydrogen sulphid no coloration or precipitation occurs salts of theheavy metals incinerate about 0 5 gm of procain accurately weighed not more than0 1 per cent of residue remains to obtain specimens representing the market supply, orders for thethree brands of procain were placed with pharmaceutical firms in newyork, baltimore and san francisco the baltimore and san franciscofirms supplied specimens of procain-novocain brand and procain-rectorbrand but reported that the abbott brand was not procurable thenew york correspondent was able to supply procain-rector only asthe entire output of the abbott laboratories was stated to go tothe government, specimens of this product were obtained through thesurgeon-general of the army from the general purchasing office, medicaldept , u s army the following specimens were obtained and examined:1 procain-abbott, 6 specimens. The first specimen bore no serialnumber but the five later specimens were designated respectively, no 89999, no 89998, no 89997, no 89996, and no 810995, representingbatches from which shipments are to be made on contracts placed by thegeneral purchasing office, medical dewritingment, u s army, with theabbott laboratories of chicago 2 procain-novocain brand, 4 specimens. These were designatedrespectively, a56, a57, a63, and a67 the first two specimens werelabeled “manufactured by the farbwerke-hoechst co at the h a metz laboratories ” the third specimen not in original containerwas labeled “h a metz laboratories” and the fourth was marked“manufactured by the h a metz laboratories ”3 procain-rector, 3 specimens. Each bore the statement “manufacturedby the rector chemical company” but had no “lot number ”from this examination it appears that all the specimens of procainreceived complied satisfactorily with all tests of identity and puritywith the following exceptions. 1 one specimen of procain-abbott hada melting point slightly below the permitted range. However, the lastfive specimens had the required melting point 2 five specimens ofprocain-abbott and the last three specimens of procain-rector were notentirely colorless, but had a yellow or light brown tinge the toxicity experiments, which were carried out by dr r a hatcherof the cornell pharmacologic laboratory, were reported as beingsatisfactory when the council on pharmacy and chemistry referred the matter ofthe discolored specimens of procain to the rector chemical companyfor explanation, the firm wrote that for a short time for essayunexplainable reason its procain had been slightly yellowish in color, but that every batch had been carefully tested and found to answer allchemical requirements the firm stated that the product which it hadsent out for essay time past had been white and yielded a colorlesssolution to a like inquiry from the council the abbott laboratories replied thatthe five samples which were found discolored were products manufacturedby the rector chemical company and represented goods which it hadpurchased to assist in filling delayed orders, because the firm hadfound itself unable to keep pace with the demand on account of delay insecuring needed apparatus the firm submitted protocols to show thatthe procain made by it, by rector and by metz were of equal toxicity in the accompanying table the results of the examination are given for comparison the findings for the specimens examined previously areincluded date melting ash brand received color point, c % procain abbott, from committee on synthetic drugs 12/21/17 white 154-155 none procain abbott, submitted to council p and c 1/29/18 white 153 5-154 5 none procain abbott, gen pur off u s army 8/31/18 white 152 5-153 5 none procain abbott, gen pur slight off u s army, no 89999 9/30/18 brownish 153 5-154 5 none tint procain abbott, gen pur slight off u s army, no 89998 9/30/18 brownish 153-154 5 0 005 tint procain abbott, gen pur slight off u s army, no 89997 10/ 8/18 brownish 153-154 none tint procain abbott, gen pur slight off u s army, no 89996 11/ 4/18 brownish 153 5-154 5 none tint procain abbott, gen pur slight off u s army, no 810995 11/ 4/18 brownish 153 5-154 5 none tint procain farbwerke hoechst co , submitted to council 10/24/17 white 153-154 none procain farbwerke hoechst co , submitted to council 12/10/17 white 153-154 5 none procain farbwerke hoechst co , submitted to council, market spec “a56” 8/ 9/18 white 153 5-154 5 none procain farbwerke hoechst co , submitted to council, market spec “a57” 9/ 9/18 white 153 5-154 5 none procain h a metz lab , market spec “a63” 8/23/18 white 153-154 none procain h a metz lab , market spec “a67” 9/23/18 white 153-154 0 018 procain rector, from com on synthetic drugs 12/18/17 white 153-154 5 none procain rector, market slight spec 8/20/18 brownish 153-155 none tint procain rector, market slight spec 8/23/18 brownish 153-155 none tint procain rector, market slight spec 8/23/18 brownish 153-154 5 none tint -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- -- so far as the evidence goes, there was nothing to indicate that theyellowish or brownish colored specimens of procain were seriouslyimpure on the contrary, the compliance with the chemical andtoxicologic tests indicated that the color was due to an insignificanttrace of essay colored substance produced in the manufacturing process in view of this, the council considered the use of the discoloredproduct to be justified in the present emergency, although it urgedthat the future supply of procain should be free from color and alsocomply to the tests of purity it made this request in the interest ofthe medical and dental professions, which use the drug, and also in adesire that in the manufacture of synthetic drugs, the united statesshould occupy a high place -- from the journal a m a , jan 11, 1919, with additions deterioration of sodium hypochlorite solutions “chlorinated soda” solutionsthe following note on two hypochlorite solutions is published as aslight addition to the inconclusive available information concerningthe rate of deterioration of solutions containing sodium hypochlorite:hyclorite -- this is a solution of chlorinated soda, 100 gm ofwhich is said to contain sodium hypochlorite 4 05 gm , sodium chlorid3 20 gm , calcium hydroxid 0 25 gm , inert ingredients 0 92 gm it isdeclared to contain, when placed on the market, not less than 3 85 percent of available chlorin, and to deteriorate at the rate of about12 per cent per year in order that the available chlorin contentat the time of use may be judged, the date of bottling is stamped oneach package the solution is prepared by decomposing chlorinated limesuspended in water with sodium carbonate and adding to the solutionobtained a freshly prepared solution of electrolyzed sodium chlorid the composition and keeping qualities of hyclorite were reported onby this laboratory ann rep chem lab , a m a 9:123, 1916 hyclorite is fully described in new and nonofficial remedies, 1918, p 153 to further check the keeping qualities of hyclorite, a specimenreceived from the manufacturer in june, 1918, and said to have beenbottled in april, 1918, was examined in september, 1918 it was foundto contain 3 6 per cent, “available chlorin” equivalent to 3 79 gm sodium hypochlorite in 100 gm this indicated a loss of 6 2 per cent during five months equivalent to 14 9 per cent per year on theassumption that it contained the amount of “available chlorin” declaredon the label concentrated solution sodium hypochlorite-mulford -- this is describedas a 5 per cent, aqueous solution of sodium hypochlorite containingfree chlorin equivalent to from 0 2 to 1 per cent sodium hypochlorite it is prepared by treating a solution of sodium carbonate and sodiumbicarbonate with chlorinated lime the solution is filtered andstandardized by determining the “available chlorin” and adjusting it tocontain the equivalent of 5 per cent of sodium hypochlorite it is proposed for use in the irrigation treatment of infected woundsafter dilution with nine times its volume of water and the additionof a determined amount stated on the label of each bottle of boricacid to render it neutral to phenolphthalein the manufacturer hasfound that development of a red color due to formation of permanganatefrom the manganese contained in the chlorinated lime is indicativeof deterioration, and therefore warns against any solution which hasbecome pink a specimen of concentrated solution of sodium hypochlorite-mulford wassent the council on pharmacy and chemistry in june, 1917, with a viewof having the product admitted to new and nonofficial remedies atthat time it was found to contain 4 18 per cent “available chlorin” equivalent to 4 4 gm sodium hypochlorite in 100 gm anotherspecimen received at the same time and kept unopened in a dark place, was examined in september, 1918, and was found to contain 2 88 percent available chlorin equivalent to 3 gm sodium hypochlorite per100 gm on the assumption that the second specimen contained, atthe time of its receipt, the amount of “available chlorin” found inthe first, this second specimen lost 31 per cent of its “availablechlorin” during fifteen months at the time the specimens were received from the mulford company, the firm reported experiments which were under way to determine thekeeping qualities of the solution these experiments indicated markeddeterioration of the specimens, which had become red from permanganateformation, and also that one specimen, which had not become red, hadlost 5 per cent of its available chlorin in one month the mulfordcompany explained that when sufficient data had been accumulated, a decision would be made either as to placing a time limit on thesolution or making a claim as to the rate of deterioration when theextreme deterioration found by this laboratory was reported to themulford company, the firm replied that this was a much greater lossthan the average deterioration found in its chemical laboratory, namely, an average of 10 or 12 per cent per year it advised thatbecause of the instability of concentrated solution of sodiumhypochlorite, its manufacture had been discontinued -- from reportsa m a chemical laboratory, 1918, p 81 syphilodolthe shortage of arsphenamin salvarsan has made the sale ofsubstitutes a profitable business in thesis of these substitutes theearmarks of dishonesty have been obvious, so that detection of theirfalsity was relatively simple in the case of “syphilodol” marketedby the french medicinal company, inc , new york, the deception hasbeen practiced more skilfully in the circular announcing theirpreparations, we read. “it seems fitting at this time, when the american physicians are doing so much for france, that there should be a reciprocation in essay way “attempting to enhance essaywhat this mutual interchange, we are presenting essay of those scientific products, which have been so successfully used in france, -- -- ” “the effect of syphilodol is very similar to salvarsan and neosalvarsan, but it has the advantage of being more lasting in its results and more pleasing in the manner of its preparations, in that it is put up in the form of tablets, and, also, in hermetically closed glass syringes or ampules, so that it may be administered either by the mouth, intravenously or intramuscularly, at the discretion of the physician patients averse to the use of the hypodermic needle may be treated expeditiously by the use of the tablet form of the medicine ”in addition to syphilodol, the french medicinal co also sells “vichifruti, ” a combination of salts, “urodol, ” an “alkaline salt of thefamous european springs which is noted for breaking up and dissolvinguric acid rapidly” and “syloiodol, ” “french preventive, ” which isdescribed as “a solution of iodol incorporated into bougie ”“syphilodol, ” we are told, is “a synthetic chemical product ofsilver, arsenic and antimony, scientifically prepared afterthe formula of the late dr alfred fournier of paris ” italicsours-- ed it is also claimed that “prof metchnikoff and other notedfrench scientists have made exhaustive tests of syphilodol and found itsuperior to the other products, in the treatment of syphilis ” in theadvertisements, fournier and metchnikoff are the only names given ofalleged endorsers. Both of these men are dead and cannot protest true, fournier did considerable work on a legitimate synthetic of antimony, silver and arsenic having a general chemical constitution similar toarsphenamin, but so far as we are aware, there has been no publicationby these men on “syphilodol ” it would seem that the valuable work andhigh reputation of fournier and metchnikoff are being capitalized bythe french medicinal company in their endeavor to foist a nostrum onthe medical profession of this country “syphilodol” comes in two forms-- ampules and tablets an order fortwo 0 4 ampules brought an elaborate case, much like those used tohold the popular style safety razors the ampule itself was a “classy”affair evidently made by a glass expert. The hypodermic needle wasenclosed in a novel sealed glass device the price of each ampule is$3 no such fancy garnishments came with the tablets, although they arelisted at $4 50 for twenty-five-- 18 cents a tablet!. in the “syphilodol”advertising it is emphasized that both the tablets and ampules are tobe administered for example. “syphilodol is dispensed in the form of tablets and also hermetically closed glass syringes or ampules so that it may be used either by the mouth, intravenously or intramuscularly at the discretion of the physician an advantage of the tablets is that they can and should be given during the interim between the injections ” laboratory report on syphilodolseveral samples of “syphilodol” were sent to the american medicalassociation chemical laboratory by readers of the journal an originalbottle of tablets was ordered direct from the french medicinal company the bottle contained 25 yellow tablets, having an average weight of0 276 gm 4-1/4 grains after being powdered, “syphilodol” was foundto be only writingially soluble in water the excipient is soluble andto be neutral in reaction these findings contradict the claims onthe circular accompanying the bottle to the effect that “syphilodolis a yellow powder, soluble in water, and has an acid reaction ”qualitative tests indicated the presence of mercury, sucrose canesugar, iodid, calcium, sulphate, fatty material, a trace of silver, a trace of arsenic and a very minute trace of antimony. A red dye wasalso present both qualitative and quantitative data showed that themercury was present in the form of mercurous iodid yellow iodid ofmercury-- hydrargyri iodidum flavum quantitative estimations yieldedthe following.

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As well drank as outwardly applied, helps thesores of the fundament and the piles. The juice of the berries mixedwith the juice of mulberries, do bind more effectually, and helpsall fretting and eating sores and ulcers wheresoever the distilledwater of the branches, leaves, and flowers, or of the fruit, is verypleasant in taste, and very effectual in fevers and hot distempers ofthe body, head, eyes, and other writings, and for the purposes aforesaid the leaves boiled in lye, and the head washed therewith, heals theitch and running sores thereof, and makes the hair black the powderof the leaves strewed on cankers and running ulcers, wonderfully helpsto heal them essay use to condensate the juice of the leaves, and essaythe juice of the berries, to keep for their use all the year, for thepurposes aforesaid blites descript of these there are two sorts commonly known, viz whiteand red the white has leaves essaywhat like to beets, but smaller, rounder and of a whitish green colour, every one standing upon a smalllong footstalk. The stalk rises up two or three feet high, with suchlike leaves thereon. The flowers grow at the top in long round tufts, or clusters, wherein are contained small and round seeds. The root isvery full of threads or strings the red blite is in all things like the white but that its leaves andtufted heads are exceeding red at first, and after turn more purple there are other kinds of blites which grow different from the twoformer sorts but little, but only the wild are smaller in every writing place they grow in gardens, and wild in thesis places in this land time they seed in august and september government and virtues they are all of them cooling, drying, andbinding, serving to restrain the fluxes of blood in either man orwoman, especially the red. Which also stays the overflowing of thewomen reds, as the white blites stays the whites in women it is anexcellent secret. You cannot well fail in the use they are all underthe dominion of venus there is another sort of wild blites like the other wild kinds, buthave long and spiky heads of greenish seeds, seeming by the thicksetting together to be all seed this sort the fishers are delighted with, and it is good and usualbait. For fishes will bite fast enough at them, if you have wit enoughto catch them when they bite borage and bugloss these are so well known to the inhabitants in every garden that i holdit needless to describe them to these i may add a third sort, which is not so common, nor yet sowell known, and therefore i shall give you its name and description it is called langue de bœuf. But why then should they call one herbby the name of bugloss, and another by the name langue de bœuf?. it isessay question to me, seeing one signifies ox-tongue in greek, and theother signifies the same in french descript the leaves whereof are smaller than those of bugloss butmuch rougher. The stalks rising up about a foot and a half high, and ismost commonly of a red colour.