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“charles loffler, buying an essay m d , or his agent was traveling around inducing one m d in each town to take up his methods of blood examination and treatment and with a little advertising of blood examinations free the doctor selected gets quite a run of patronage ”another physician writes. “my attention has been called by another physician to loffler intra-venous compound may i trouble you to give me any information that you may have with regard to its composition and its value as a therapeutic agent?. ”c l loffler does business from rooms 1101-1102, venetian bldg , chicago, the location of the “intravenous chemical co , ” the“physicians drug syndicate” and the “ma-oze chemical co ” of these, more later the journal has in its files a large amount of materialregarding loffler a brief résumé of that writing of the material dealingwith loffler professional activities will be given for the purposeof allowing physicians to evaluate the scientific status of loffler“lectures, ” “post-graduate courses, ” his therapeutic “discoveries” andhis products it seems that loffler was reared in yankton, s d in 1898-1899, loffler was a senior student at john creighton medical college, but, for reasons that need not be gone into here, he was never graduated he received a diploma from barnes medical college in 1900, and in thesame year was licensed to practice in south dakota in 1902 he was atle mars, iowa.

Chloride of methyl, 16 per cent. Bromide of ethyl, 1 per cent ”although somnoform has been on the market for a long time, thepublished reports present no proof that it is superior to ethylchlorid used alone moreover, the published reports and statistics donot necessarily apply to the somnoform now sold for the reason thatmixtures of varying composition have been sold as somnoform in thepast thus, when somnoform was considered by the council in 1909, itwas claimed to be composed of chloride of ethyl, 60 per cent. Chlorideof methyl, 35 per cent , and bromide of ethyl, 5 per cent federalchemists found, however, that it contained no bromide of ethyl noticeof judgment no 571 it is a question, therefore, whether a givenreport applies to a mixture containing 5 per cent bromide of ethyl, 1per cent of this substance, or none at all the present advertising booklet for somnoform does not presentacceptable evidence of the therapeutic value of the preparation an ignorance concerning the elementary facts of physiology andpharmacology is evident in the second sentence. When having stated that“somnoform is the result of several years of study and investigation bydr george rolland, dean of the bordeau dental school, ” the pamphletcontinues. “he sought an anesthetic which would enter, dwell in, andleave the body in the same manner that oxygen does ”the claim as to the value of the 1 per cent of ethyl bromide in themixture is highly improbable. Certainly no evidence in support of theclaimed value of this constituent is available to the referee no evidence is submitted which proves the claim of superiority ofsomnoform over similar preparations, asserted in the following. “the peculiar manner in which the elements are combined is what makes somnoform at once so efficient and so safe ”the council declared somnoform inadmissible to new and nonofficialremedies because, in the absence of acceptable evidence showing itsexceptional safety and value, the claims are unwarranted rule 6, andbecause the name of the mixture is not descriptive of its composition rule 8 -- from reports of council on pharmacy and chemistry, 1919, p 90 tablets formothalates report of the council on pharmacy and chemistrythe council has authorized publication of the following report whichdeclares tablets formothalates tailby-nason company, boston, mass ineligible for new and nonofficial remedies w a puckner, secretary tablets formothalates are sold by tailby-nason company, boston, mass on the label a formula is given. “constituents. Acetanilid2 gr. Phenolphthalein 1/2 gr in a balanced combination withhexamene a name essaytimes applied to hexamethylenamin and oil ofcinnamon indications. Influenza, colds, grippe, headache, neuralgia, rheumatism ” the same formula is given in advertisements and in thisadvertisement it is claimed that they are “for influenza and grip” andif “given in the acute stage may avert a serious attack” boston m & s j , oct 3, 1918 the dose is given as one to two tablets at6 p m and repeat at bedtimes the a m a chemical laboratory reported that the tablets weigh anaverage of 0 4882 gm , or 7-1/2 grains. That they have the odor andtaste of cinnamon. And that they contain hexamethylenamin, are neutraland therefore give up no formaldehyde in the presence of water alone the laboratory further reported that they contain phenolphthalein andacetanilid these tablets were directed to be taken internally andtherefore their effect was not intended to be local the amount of hexamethylenamin was not determined, but in any casecould not exceed 5 grains per tablet it is evident that 4 grainsof acetanilid and 10 grains of hexamethylenamin and 1 grain ofphenolphthalein in two tablets “if given in the acute stage” ofinfluenza would not “avert a serious attack, ” as claimed in theadvertisements the council declared tablets formothalates inadmissible to new andnonofficial remedies -- from reports of council on pharmacy andchemistry, 1919, p 92 triple arsenates with nuclein report of the council on pharmacy and chemistrythe council has declared triple arsenates with nuclein no 1 andtriple arsenates with nuclein no 2, tablets marketed by the abbottlaboratories, inadmissible to new and nonofficial remedies becauseunwarranted therapeutic claims rule 6 are made for them and becausethey present an illogical combination of drugs rule 10 thepublication of the following report has been authorized by the council w a puckner, secretary the following claims are made for triple arsenates with nuclein.

Besides they are good to cure horses of thebots calamintha, montana, palustris mountain and water calamint. Forthe water calamint. See mints, than which it is accounted stronger mountain calamint, is hot and dry in the third degree, provokes urineand the menses, hastens the birth in women, brings away the placenta, helps cramps, convulsions, difficulty of breathing, kills worms, helpsthe dropsy. Outwardly used, it helps such as hold their necks on oneside. Half a dram is enough at one time galen, dioscorides, apuleius calendula, &c marigolds the leaves are hot in the second degree, and essaything moist, loosen the belly. The juice held in the mouth, helps the toothache, and takes away any inflammation or hot swellingbeing bathed with it, mixed with a little vinegar callitricum maiden-hair see adianthum caprisolium honey-suckles. The leaves are hot, and therefore naughtfor inflammations of the mouth and throat, for which the ignorantpeople oftentime give them. And galen was true in this, let modernwriters write their pleasure if you chew but a leaf of it in yourmouth, experience will tell you that it is likelier to cause, thanto cure a sore throat, they provoke urine, and purge by urine, bringspeedy delivery to women in travail, yet procure barrenness and hinderconception, outwardly they dry up foul ulcers, and cleanse the facefrom morphew, sun-burning and freckles carduncellus, &c groundsell cold and moist according to tragus, helps the cholic, and gripings in the belly, helps such as cannot makewater, cleanses the reins, purges choler and sharp humours. The usualway of taking it is to boil it in water with currants, and so eat it i hold it to be a wholeessay and harmless purge outwardly it easethwomen breasts that are swollen and inflamed. As also inflammations ofthe joints, nerves, or sinews ægineta carduus b mariæ our ladies thistles they are far more temperatethan carduus benedictus, open obstructions of the liver, help thejaundice and dropsy, provoke urine, break the stone carduus benedictus blessed thistle, but better known by the latinname. It is hot and dry in the second degree, cleansing and opening, helps swimming and giddiness in the head, deafness, strengthens thememory, helps griping pains in the belly, kills worms, provokes sweat, expels poison, helps inflammation of the liver, is very good inpestilence and venereal.

That they consist solely of naphthenes and polynaphthenes brooks confirms this statement so buying an essay far as american liquid petrolatumsare concerned he states that thesis american petroleums, such as mostof those from the gulf region, are like the russian in containing noparaffin. And that, in the case of those petroleums that do containit, the customary refinery method of removing paraffin is sufficientto produce true naphthene and polynaphthene petrolatums “the claimthat only russian oils belong in this class, ” he says, “has no basisin fact and has been advanced presumably for business reasons ” thename “paraffin oil” applied to these liquid petrolatums, then, is amisnomer the new name, “white naphthene oils, ” suggested by brooks, seems superfluous, however, since the pharmacopeial title, “liquidpetrolatum, ” is subject to no such objection -- editorial from thejournal a m a , jan 1, 1916 the lowenthal postgraduate course which tells how to make diagnoses accurately, scientifically check the christian scientists and increase your earning powerduring the past year the journal has received letters from physiciansin various cities asking for information regarding the “post graduatecourse of lectures and clinics on nervous and mental diseases” whichwas going to be given in their respective cities by dr albert a lowenthal of chicago the following inquiries are typical. “to the editor -- please note the enclosed letter from the american organotherapy company which appears to be conducted by lowenthal the proposition of conducting these clinics impresses me as a piece of colossal gall which is amazing even in these days do you know anything about this matter?. ” “to the editor -- who the dickens is albert a lowenthal, m d ?. note the circular enclosed i have blue circled the remarks he evidently thinks will attract ”in may, 1919, chicago physicians received a form letter, signed, and on the stationery of, albert a lowenthal, notifying them thatdr lowenthal was about to “give a post graduate course of lecturesand clinics on nervous and mental diseases” in the “banquet hall, morrison hotel ” enclosed was a “programme and reservation card” anda self-addressed envelop for physicians to notify dr lowenthal thatthey would be present in addition to showing physicians “how to makediagnoses accurately, ” dr lowenthal offered to “explain fully how toscientifically check the christian scientists and increase your earningpower!. ” and all for nothing!. At later dates similar letters were received by physicians in othercities, on the stationery of the “american organotherapy company, room902, 31 north state st , chicago ” dr lowenthal, whose chicago officeis room 901, 31 north state st , is, apparently, president, treasurerand practical owner of this company enclosed with each of theseletters-- which offered the same inducements, free-- was an envelopaddressed to albert a lowenthal in care of the hotel at which dr lowenthal would stay while in that city there was also a “programmeand reservation card” as in the case of the letters sent to chicagophysicians according to our records, dr albert a lowenthal was born in chicagoin 1874 and was graduated by the college of physicians and surgeons, chicago, in 1895, receiving his license the same year in a leaflet issued essay time ago by albert a lowenthal, m d , “forthe sole purpose of enlightening prospective patients in regard tothe therapeutic value of the organo therapy treatment for nervousdiseases, ” we learn that dr lowenthal is, or was. “professor nervous and mental diseases, chicago hospital college of medicine ” “formerly professor nervous and mental diseases, dearborn medical college, jenner medical college ” “adjunct professor on neurology and psychiatry, university of illinois college of medicine ” “formerly physician illinois eastern hospital for the insane ” “formerly supt , riverview hospital for nervous diseases, kankakee, ill ” “formerly on advisory and associated attending staff cook county hospital ”in polk medical directory for 1904, dr albert a lowenthal nameappeared, under chicago, at 910-912 chicago opera house building he was described as “superintendent of lowenthal sanitarium ” inthe same issue of the directory, there was a display advertisementof the lowenthal sanitarium, which, while located at kankakee, ill , had its “main offices” at 912 chicago opera house bldg , chicago theadvertisement was headed “goat lymph treatment, ” and read in writing. “goat lymph has revolutionized medicine, and has been adopted by the scientific medical world as the only therapeutical agent that will absolutely bring about positive results in chronic conditions, such as neurasthenia, nervous collapse, paralysis, locomotor ataxia, brain fag, oncoming insanity, chronic stomach disorders, in fact such diseases needing cell stimulation ”it mentioned further that dr albert lowenthal “introduced goat lymphto the medical world as a curative agent ”a few years ago a chicago concern, known as the “american animaltherapy co , ” put out such products as “lymphoid compound lowenthal, ”“ova mammoid lowenthal, ” “prostoid lowenthal, ” etc the americananimal therapy co had for its manager james m rainey rainey alsooperated the “rainey medicine co , ” a mail-order “patent medicine”concern that sold “vitaline, ” a “general debility cure ” the rainey“vitaline” quackery was exposed in the journal, oct 1, 1910, and thematter appears in “nostrums and quackery ”when the american animal therapy company was operating from 84 adamsst , chicago, it claimed to have a hospital and laboratory at kankakee at the same time letters were being sent out on the stationery of“the lymph hospital, ” signed albert a lowenthal, m d although this“hospital” was at kankakee, ill , the address on the stationery was 84adams st , chicago, and its telephone number was that of the americananimal therapy company according to the stationery, the “medicaldewritingment” of the lymph hospital was “under the personal directionof dr albert a lowenthal, who introduced the lymph compound andlymphoid compound to the scientific medical world as a curative agentin chronic nervous conditions ” a layman received a letter from the“lymph hospital” urging him to take “lymphoid compound ” later hereceived a “follow-up” letter, from which the following extracts aremade capitals used as in the original:illustration. Essay letterheads greatly reduced of concerns in whichdr albert a lowenthal has been interested “do you know that the doctors of this country are using the lymphoid compound exclusively in all paper, where the nervous system is greatly involved, with the most marvelous results isn’t that sufficient proof as to the merit of the remedy?. ” “ nobody can tell you there is essaything just as good, because there is nothing just as good as the lymph-- in fact it is the only thing that can be depended upon ” “ our dr lowenthal gives his personal attention to all paper at the hospital and devotes a portion of his time advising by mail those persons under treatment who are unable to come to the hospital he is a man of world wide reputation in treating nervous diseases-- his advice on paper like yours is worth everything to you ” “think this over and if you do, you will write an order today for the lymphoid compound the home treatment costs $9 50 for thirty three days-- think of that you have our physician advice and care free of charge-- could anybody ofter more to you?. ”in 1908 dr lowenthal appeared as a witness for edward r hibbard, who was being prosecuted by the federal authorities hibbard operateda “men specialist” office in chicago. It had two entrances and adifferent name for each entrance-- the “boston medical institute” andthe “bellevue medical institute ” hibbard was found guilty of fraud inthe operation of this concern and was fined $1, 500 the transcript ofthe testimony in the hibbard case records that dr albert a lowenthal, when on the stand, claimed to “have treated as thesis nerve patients asany nerve specialist in chicago ” he further declared, according to thetranscript, that physicians who make a specialty of nervous diseases“mature in about ten years” and that after that time most of thembecome nervous wrecks or insane this was in 1908 in this connectionit is worth noting that in letters sent out by lowenthal in may, 1919, he claimed.

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Nor are we awarethat any competent investigator has done so there is, to the best ofour knowledge, no scientific evidence on which to base the claims forprotonuclein beta the council reaffirms its former action with regard to protonuclein the objections made to protonuclein apply with equal force toprotonuclein beta in view of the lack of evidence, the claims forprotonuclein beta are unwarranted and the product is ineligible ton n r on account of noncompliance with rules 1, 6 and 8 -- from thejournal a m a , jan 1, 1916 hydropsin report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary hydropsin is marketed by the ernst bischoff company, inc , new york its composition is thus described. “hydropsin is the standardized dialysate of digitalis purpurea, betula alba, scilla maritima, juniperis communis, and herniaria glabra. Or, stated otherwise, it is the juice of these drugs, dialyzed and physiologically standardized ” “each fluid dram represents digitalysatum 7 gtts , and 2 gtts each of the dialysates of betula, herniaria, juniper and scilla ”the composition of hydropsin must be considered essentially secretsince the amounts of the several constituent drugs in a given amountof “dialysate” are not disclosed the active principle of juniper is avolatile oil which is practically insoluble in water. It is difficultto believe that the “juice” of juniper submitted to dialysis couldcontain any material amount of the active constituent no informationis given as to the method used whereby the several dialysates are“physiologically standardized ” it therefore remains to be provedthat the manufacturer of hydropsin possesses any method whereby thedialysates of juniper juniperis communis, birch betula alba, the common european birch and knot weed herniaria glabra are sostandardized the claim is made that. “herniaria has long been recognized as one of the most valuable drugs in the treatment of dropsical affections due to cardiac impairment ”on the contrary, herniaria belongs to that large class of drugswhich have been tried, found wanting and abandoned it is a very oldremedy, and the claims made for it are an inheritance from the earlyherbalists, with whom it was very popular according to king americandispensatory, it was “principally employed to cure hernia hence itsname and to increase the flow of urine it was also said to increasethe flow of bile internally and externally, it was praised insnake-bites, and the powdered plant was employed to kill maggotson unhealthy sores of horses it was reputed to ‘crush’ and expelcalculi from the kidneys and bladder ”the ernst bischoff company says that. “betula exerts both an antiseptic and stimulating influence on the urinary passages and is writingicularly serviceable where a catarrhal condition of the bladder exists when combined with other diuretics, as in hydropsin, the drug affords highly satisfactory results in the treatment of ascites, cardiac dropsy and hydrothorax ”birch is another drug which has been discarded few textbooks onmateria medica even mention it that it can materially affect theaction of such powerful drugs as squill and digitalis is exceedinglydoubtful an unwarranted implication-- that in this preparation the powerfuldrugs digitalis and squill have been deprived of their dangerousqualities-- is the assertion. “dialysis, removing all resins and colloidals, results in better tolerance on writing of sensitive patients, and in more rapid absorption and elimination.