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Either cold bynature, or cooled by accident, by which natural heat is cherished whenweak, or restored when wanting effect 1 the first effect then of medicines hot in buy custom paper the first degree, is, by their sweat and temperate heat to reduce the body to itsnatural heat, as the fire doth the external writings in cold weather, unless the affliction of cold be so great that such mild medicines willnot serve the turn effect 2 the second effect is, the mitigation of pain arising fromsuch a distemper, and indeed this effect hath other medicines, essaythat are cold, and essay that are hotter than the first degree, theybeing rationally applied to the distemper these medicines the greekscall anodyna, and shall be spoken of in their proper places in thisplace let it suffice that medicines hot in the first degree, makethe offending humours thin, and expel them by sweat, or insensibletranspiration, and these of all others are most congruous or agreeableto the body of man, for there is no such equal temperature of heatand cold in a sound man, but heat exceeds, for we live by heat andmoisture, and not by cold medicines then which are hot in the first degree, are such as justcorrespond to the natural heat of our bodies. Such as are hotter orcolder, are more subject to do mischief, being administered by anunskilful hand, than these are, because of their contrariety to nature;whereas these are grateful to the body by their moderate heat effect 3 thirdly, these take away weariness, and help fevers, beingoutwardly applied, because they open the pores of the skin, and bytheir gentle heat prepare the humours, and take away those fuliginousvapours that are caused by fevers discommodities yet may discommodities arise by heedless givingeven of these, which i would have young students in physic to be verycareful in, lest they do more mischief than they are aware of, viz it is possible by too much use of them, to consume not only what isinimical in the body, but also the substance itself, and the strengthof the spirits, whence comes faintings, and essaytimes death. Besides, by applying them to the writings of the body they are not appropriatedto, or by not heeding well the complexion of the patient, or thenatural temper of the writing of the body afflicted, for the heart is hot, but the brain temperate effect 4 lastly, medicines hot in the first degree, cherish heat inthe internal writings, help concoction, breed good blood, and keep it goodin temper, being bred of medicines hot in the second degree these are essaything hotter than the natural temper of a man use their use for such whose stomachs are filled with moisture, because their faculty is too hot and dry. They take away obstructionsor stoppings, open the pores of the skin, but not in the same mannerthat such do as are hot in the first degree, for they do it withoutforce, by a gentle heat, concocting, and expelling the humours, bystrengthening and helping nature in the work. But these cut toughhumours, and scatter them by their own force and power when naturecannot of medicines hot in the third degree those which attain the third degree of heat, have the same facultieswith those before mentioned. But as they are hotter, so are they morepowerful in their operations, for they are so powerful in heating andcutting, that if unadvisedly given they cause fevers use their useis to cut tough and compacted humours, to provoke sweat abundantly;hence it comes to pass they all of them resist poison of medicines hot in the fourth degree those medicines obtain the highest degree of heat, which are so hotthat they burn the body of a man, being outwardly applied to it, andcause inflammations, or raise blisters, as crowfoot, mustard-seed, onions, &c of these more hereafter of cooling medicines physicians have also observed four degrees of coldness in medicines, which i shall briefly treat of in order of medicines cold in the first degree those medicines which are least cold of all, obtain the first degree ofcoldness. And i beseech you take notice of this, that seeing our bodiesare nourished by heat, and we live by heat, therefore no cold medicinesare friendly to the body, but what good they do our bodies, they do itby removing an unnatural heat, or the body heated above its naturaltemper the giving then of cold medicines to a man in his natural temper, theseason of the year also being but moderately hot, extinguishes naturalheat in the body of man yet have these a necessary use in them too, though not so frequent ashot medicines have. And that may be the reason why an all wise god hathfurnished us with far more hot herbs and plants, &c than cold use 1 their use is first, in nourishment, that so the heat of foodmay be qualified, and made for a weak stomach to digest use 2 secondly, to restrain and assuage the heat of the bowels, andto cool the blood in fevers therefore if the distemper of heat be but gentle, medicines cold inthe first degree will suffice. Also children, and such people whosestomachs are weak, are easily hurt by cold medicines of medicines cold in the second and third degree use 1 such whose stomachs are strong, and livers hot, may easilybear such medicines as are cold in the second degree, and in paper ofextremity find much help by them. As also by such as are cold in thethird degree, the extremity of the disease considered, for by boththese the unbridled heat of choler is assuaged use 2 also they are outwardly applied to hot swellings, dueconsideration being had, that if the inflammation be not great, usethose that are less.

-- ed i am sure you will agree with me that it would be possible to findphysicians who would be willing to put up thesis hundreds of dollars toguarantee that neither cancer nor sarcoma can at the present time becured except by operation and i can recall thesis paper in my lifetimewhen i paid hundreds and even thousands of dollars to be cured ofdiseases by the medical profession, and i am unable to recall a singlecase where i was ever cured of anything still this need not be anindictment of scientific medicine -- ed finally, as regards to the subject of mercenary motives, permitme to state that i have in my possession a letter from dr abramsstating that what he desires is to have established an institute forthe purpose of making his work known to the world, and that if suchan institute is established he is prepared to give up all his otherwork and devote all his time, without compensation, to the institute furthermore, he is willing to furnish his instruments without charge toany medical institution which requests them within the last few days, on account of the enormous number of blood specimens brought into hisclinic, dr abrams has signed in my presence, and is prepared to issuea statement to the effect that his charge for examining blood specimensis to be raised from $10 00 to $25 00 and all checks are to be madepayable to a trust fund which is to be immediately established, for thepurpose of founding the institution above referred to i do not see howthe medical profession can ask for more than this. But if you do, ishould be pleased to receive your suggestions and transmit them to myfriend an old storynow, this failure to recognize a great medical discovery is an oldstory it was the experience of harvey we knew poor harvey would bedragged into this -- ed , of jenner and of lister but the world moveson, and men brains should improve, and it should be possible toshorten the time of persecution which the great pioneers of sciencehave to suffer i put to you this simple proposition. Send a reliableman of science to the clinic of albert abrams, and let him stay thereas long as he pleases and see all that he wishes to see, and then sendyou a report, and if it indicates that you have blundered in yourcondemnation, be honest and say so, and save your profession fromanother black mark against its name upton sinclair, pasadena, cal commenta testimonial is of value to the extent that the person giving itis an authority on the subject on which he testifies when mr sinclair testifies on socialism we may listen respectfully, believinghim competent to express an opinion. But when mr sinclair gives atestimonial on certain bizarre methods of interpreting difficult andobscure problems in medicine, he leaves us cold mr sinclair says that he has spent time in dr abrams’ clinic and iswonderfully impressed with dr abrams’ achievements so is the smallboy impressed with the marvelous facility with which the magicianextracts the white rabbit from the silk hat mr sinclair is convinced“that albert abrams has discovered the great secret of the diagnosisand cure of all the major diseases ” the small boy is equally convincedthat the prestidigitator has solved the mystery of producing snow whitebunnies from airy nothings great store seems to be placed by mr sinclair on the favorablereports that he obtained from those who are relieving the public-- offrom $1, 000 to $2, 000 a week-- by the abrams methods of diagnosisand treatment what kind of evidence did he expect to get from suchobviously ex writinge sources?. mr sinclair naïveté may be childlike, but it is not scientific while the significance of the statement maynot be apparent to mr sinclair, it is a fact that when the names ofthe one hundred or more lessees of the abrams “oscilloclast” werechecked up it was found that a number of these individuals were alreadyin the propaganda files in essay other connection that these disciplesof abrams, who are “enjoying incomes of from $1, 000 to $2, 000 a week, ”should speak favorably of the abrams method was inevitable!. Essay years ago upton sinclair wrote a book on his at that timepanacea for human ailments it was the “fasting cure ” at that timehe told of individual acquaintances suffering from various ailments:one was “dying of kidney trouble”. Another was “in the hospital fromnervous breakdown”. Still another had “only a year to live, ” while afourth was “a nervous wreck, craving for death ” of these mr sinclairsaid at the time. “and there is not one of these people whom i couldnot cure if i had him alone for a couple of weeks ” mr sinclair and the medical professionat that time mr sinclair was greatly perturbed at the attitude ofthe medical profession toward his dictum that “the fast is natureremedy for all diseases ” there was just one physician “who was reallyinterested ” this man lived “in an out of the way town in arkansas” andasked sinclair to “let him print several thousand copies of the articlein the form of a pamphlet to be distributed among his patients ” asmr sinclair said at the time, “one single mind among all the 140, 000physicians, open to a new truth!. ” and this “open mind, ” that of aman who was practicing in a small town in arkansas and needed “severalthousand copies” of the sinclair article to distribute to his patients!. After his “fasting cure” experience, mr sinclair had the “raw food”fad-- also abandoned in due time in one of his recent books “the brasscheck” he refers to his outgrown fads in the following words. “i was willing to try anything in the hope of solving the health problem, which i have since realized is insolvable-- there being no diet orsystem of any sort which will permit a man to overwork with impunity ”he states further in this same connection:“i look back in retrospect and have not a little fun over my ‘monkeydiet’ days ”who shall say that ten years hence mr sinclair may not be able tolook back, good humoredly, in retrospect, to another time when he was“monkeying” with a subject that was beyond his ken?.

The liquid has a slight opalescence thereis considerable deposit of a heavy black precipitate does not becomehomogeneous buy custom paper on shaking and the black substance quickly separates again collosol cuprum, 0 5 per cent. Dark red essaywhat opalescentliquid no precipitate may be colloidal collosol ferrum, 1-2000. Liquid clear large quantities of dark brownflocculent precipitate the precipitate is not distributed evenly whenthe mixture is shaken and settles out quickly on standing collosol hydrargyrum, 5 per cent. Milky liquid large quantities ofwhite deposit mixed with considerable black the deposit mixes fairlywell but the greater writing settles out after standing an hour or two collosol manganese, 2 5-1000. Clear reddish-brown liquid withoutdeposit of any kind is not opalescent or fluorescent collosol iodin, 1-500. Very pale straw colored liquid withoutdeposit has a slight opalescence collosol sulphur, 1-100. Liquid is opalescent there is essay depositof yellow writingicles a four ounce bottle was also submitted the liquidin this bottle is milky with considerable deposit of yellow crystalslike ordinary crystalline sulphur collosol cocain, 1-100. Transparent, colorless liquid with nodeposit chemical examination showed 0 4 per cent of what may havebeen cocain this residue gave alkaloidal tests collosol quinin, 1-100. Slightly opalescent, colorless liquid, withno deposit gives alkaloidal reactions -- from the journal a m a , june 7, 1919 pulvoids calcylates compound report of the council on pharmacy and chemistrythe council has authorized publication of the following report, notso much because the preparation with which it deals is of any greatimportance, but as a protest against the large number of similarirrational complex mixtures which are still offered to physicians w a puckner, secretary pulvoids calcylates compound the drug products co , inc are tabletseach of which is claimed to contain. “calcium and strontium disalicylate, 5 grs. Resin guaiac, 1/2 gr. Digitalis, 1/4 gr. Cochium colchicum?. seed, 1/4 gr. Squill, 1/4 gr. Cascarin, 1/16 gr with aromatics ”“pulvoids calcylates compound sugar coated orange color”is advertised medical times, january, 1919 as being“analgesic-antipyretic and diuretic, ” and is included in thepreparations designated by the advertiser as “approved remedies forlagrippe and ‘flu ’” the claim that “their tolerance is remarkable”refers not to the physicians who tolerate such products, but to thealleged fact that pulvoids calcylates are tolerated remarkably well the advertisement continues.

Official report of council on pharmacy andchemistry-- with comments, j a m a 47:1751 nov 24 1906 the issuance of a patent for a medicinal product does not prove thatsuch a product presents a discovery or that its owner is entitled toa temporary monopoly, yet it is only fair to physicians and to othermanufacturers that notice of such patent claims be given hence, thecouncil publishes in new and nonofficial remedies the informationbearing on this point lay advertising -- rules 3 and 4 provide against the recognition ofarticles that are advertised to the public directly or indirectly, exempting from this requirement preparations which the council believesare safe to be so advertised it has been held with essay justice that certain shotgun proprietariesare purchased by the public with as much circumspection as they areordered by those physicians who are addicted to the prescribing ofthem. But even the exploiters of these mixtures have not denied thatthe use of medicines by the public on its own initiative is surroundedwith thesis objections hence the practice of self medication should notbe encouraged by prescribing or using those preparations advertised forpublic use the only objection to the rule has come from a firm which markets abrand of liquid petrolatum, the standard oil company of indiana thecouncil has considered the question of exempting simple laxatives fromthe restrictions of rules 3 and 4 as it has exempted antiseptics andnonmedicinal foods the conclusion was, however, that the excessiveuse of a simple laxative like a liquid petrolatum, when prompted bynewspaper exploitation, is likely to be detrimental to health byoveruse as well as by misuse the indirect advertisement to the public, which rule 4 providesagainst, has been the means of inducing the extensive lay use of“antikamnia, ” “bromidia” and “fellows’ syrup ” naturally rule 4 hasbeen bitterly opposed by most proprietary firms arguing that thesisphysicians dispense their own drugs, pharmaceutical firms have insistedthat every medicinal preparation should bear on its label, not onlythe dose of the preparation, but also a statement of the diseases inwhich the article is indicated whether manufacturers anticipated theprofession resentment toward the claim that physicians determinethe treatment and perhaps the diagnosis by means of the statements onlabels, or because the shirley amendment to the food and drugs actmakes the proprietor responsible for therapeutic claims on the labelof a medicine, it is a fact that fewer preparations than formerly needto be refused on account of infringement on this rule in fact, essaythoroughly objectionable proprietaries make a show of being “ethical”by omitting all therapeutic discussion from the labels of theirpreparations therapeutic claims -- rule 6 makes ineligible for new and nonofficialremedies any articles regarding which the manufacturer or hisagents make unwarranted, exaggerated or misleading statements as tothe therapeutic value recognizing the long established custom oftherapeutic exaggeration, it has been most difficult to determinethe degree of conservatism which might with fairness be requiredof a manufacturer in view of the common acceptance of individualimpressions as dependable evidence, it is often almost embarrassingto declare as incompetent the statement of essay well meaning andall-too-kind-hearted doctor however, as the pitfalls of haphazardclinical trials become better known and the physician mistrust ofglowing accounts of marvelous cures more outspoken, the manufacturers’claims will be more moderate nomenclature -- were it possible to enact and enforce a law whichwould oblige manufacturers to sell their medicinal products underproperly descriptive names and which would make it illegal for aphysician to prescribe it unless he understood the meaning of suchproperly descriptive titles, then the council might safely disband inthat case, physicians would discontinue the use of most proprietarypreparations in favor of established drugs, and successful newcomersmight each year be counted on the fingers of one hand such a rationalnomenclature is not to be thought of, at least in our generation rule 8 requires that the name of an article shall not be misleading, that it shall not be therapeutically suggestive, and that establisheddrugs shall not be disguised by fanciful titles it recognizes theright of discoverers of new drugs to name their discoveries, andinterposes no objection to arbitrary names for such products so longas such names are not misleading or do not suggest the therapeuticuses of the products as the rule provides against the recognition ofcoined names for established nonproprietary drugs, so it requires thatmixtures of drugs shall bear names descriptive of their composition it would be a long step forward if physicians would recognize morefully the objections to the thesis proprietaries which have, as theironly point of originality, a non-descriptive name for an old drug ora mixture of well known drugs it is an encouraging sign that thefederal trade commission, when issuing licenses for the manufacture ofsynthetic drugs introduced under german patents, stipulated that allmanufacturers authorized to make a given drug shall use the same namefor it irrational articles -- rule 10 provides against the recognition ofan article which, because of its composition, is useless or inimicalto the best interests of the public and medical profession thisrule excludes medicaments which 1 are unessential modifications ofestablished articles, or 2 are of no therapeutic value or 3 areirrational with regard to the recognition of mixtures or compoundscontaining two or more active ingredients, the council requires thatthe manufacturer establish the rationality of its combination the rulehas prevented the recognition of thesis unnecessary so-called ethicalspecialties though a mass of testimonials was often to be had forthem, these contained no evidence that the mixture was superior to itspotent ingredient, or that its therapeutic effect had been determined that there is a healthy tendency to use single drugs for their definiteaction and to discard combinations be they shotgun proprietaries or“mixed” vaccines is perhaps best illustrated by the fact that atthe last revision of the u s pharmacopeia a considerable number ofcomplex antiquities were omitted from that book feeling confident that this meets with the endorsement of theprofession, the council is examining more critically the evidence forthe value of pharmaceutical mixtures -- from the journal a m a , may10, 1919 “accepted by the council on pharmacy and chemistry”under the caption given above, the journal of the missouri statemedical association, in its july issue, speaks editorially as follows:the council on pharmacy and chemistry of the american medicalassociation is a dewritingment of our national organization that hasnot received the plaudits and encomiums of a wildly joyous medicalprofession nor the grateful praises of the enthusiastic manufacturerof pharmaceuticals the council seems indeed to be the unloved childof the entire family of subsidiary bodies of the association perhapsthe reason for this may be found in the character of its duties, forthe council must expose fraud, essaytimes in high places, and protectthe physician from being duped by avaricious persons and by personswho are themselves essaytimes the victims of their own credulity itthus happens that the sale of essay proprietary article previously heldin high esteem by the practitioner proves valueless, perhaps evenfraudulent the practitioner, however, may have credited much of hissuccess in treating certain conditions to that preparation and themaker has had success in accumulating dollars from its sale and bothwritingies emit a loud and vicious roar against the council, becausethey both lose money nobody wants to be “protected” against makingmoney-- make it honestly, if possible, but make it-- but this black sheepamong the councils of the american medical association insists on theirmaking their money honestly!. Despite thesis obstacles thrown into its path, the council on pharmacyand chemistry has serenely pursued its allotted tasks, correctedits mistakes, improved its methods, and today stands as the onlymedium to which the honest physician may turn for information-- notmisinformation-- regarding proprietary articles during the war thecouncil and the chemical laboratory were in close cooperation withthe surgeon-general office, testing and investigating every articleoffered to the government for the treatment of sick soldiers thevariety and the number of fakish and fraudulent stuff offered to thesurgeon-general was a pitiable exhibit of the mental gymnastics ofessay people just now the council and the laboratory have a new andimportant field before them, i e , to protect the physicians againstworthless and useless serums, vaccines and synthetics it will be thecouncil unpleasant duty to expose the fraudulent and useless amongthese articles and stamp truth on those found worthy we seem to have wandered from the topic in our caption, but not so inreality, because the burden of our thought is to lend our influence tothe spread of the motto of the advertising clubs of the world, namely, “truth in advertising ” it is our purpose to stimulate a larger degreeof enthusiasm for the work of the council on pharmacy and chemistryand the chemical laboratory, a more generous flow of inquiriesconcerning articles unfamiliar to the physician, and writingicularly tourge that the words “accepted by the council on pharmacy and chemistryof the american medical association” be printed on the label and onall advertising circulars of proprietary articles that have beenadmitted to new and nonofficial remedies then, when pamphlets andcirculars are received by physicians they will read the statements ofmanufacturers with sympathetic understanding and with full confidencein the verity of the declarations the importance of creating justthat sort of receptivity in the mind of the prospective buyer is sowell known to the astute publicity expert that it is needless forus to dwell on its advantages every proprietary article advertisedin our journal, in the journal of the american medical association, and in the other state association journals, as well as in severalwell-edited privately owned journals, does in effect say to the readerthat the articles so advertised are accepted by the council becauseonly proprietary articles so accepted are accepted by us the fact isfurther acknowledged when these firms are permitted to exhibit theirgoods at our annual sessions for again the rule is enforced that onlyproprietary articles which have been approved by the council may beplaced on display why not complete the circle of ideas-- it would not be a “viciouscircle”-- by printing on labels, in advertisements and circulars, thewords. “accepted by the council on pharmacy and chemistry”?. -- from thejournal a m a , aug 2, 1919 helping the councilif they were built that way, the members of the council on pharmacy andchemistry of the american medical association might become discouragedat the apparent indifference of thesis members of the medical professionto their efforts there are thesis physicians who, while figurativelypatting the council on the back, actually do nothing to aid itsefforts on the other hand, there are men in the profession who givethe council active support instead of merely passive appreciation the letter that follows was written by such a man to a pharmaceuticalconcern. I am receiving circular advertising from you concerning -- -- -- -- solution, and i am writing to suggest that until these products have been approved by the council on pharmacy and chemistry of the american medical association, you are wasting your postage on the practice aside from the fact that these products do not appeal to me personally, i feel that i am not in a position to judge the value of such products and i depend entirely on the large clinical opportunities of the council on pharmacy and chemistry of the american medical association in addition to their laboratory facilities, in such matters as these i may, therefore, with all due respect, suggest that it will pay you to eliminate my name from your mailing list the members of the council on pharmacy and chemistry are working weekin and week out without remuneration few appreciate how much thesescientific men are doing for rational therapeutics. Fewer still realizehow much has been accomplished through their efforts, or how much morecould be accomplished if every physician who at least believes in thework of the council would give it his full support -- editorial fromthe journal a m a , nov 6, 1920 delays in passing on products report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary the council frequently receives inquiries-- essay of them accompanied byexpressions of impatience-- concerning articles, reports on which appearto be delayed it therefore seems advisable to make a statement of essayof the factors which enter into this problem the council fully realizes the importance of giving prompt informationto the profession with regard to proprietary medicines underconsideration it therefore acts as soon as sufficient informationis available to justify a definite judgment, and publishes itsconclusions as soon as possible when adequate information is availableat the outset, there is no delay in the publication of the councilconclusions unfortunately, but very naturally, there are thesis paper in which theinformation available at the time the product is submitted is notsufficient to justify the council in coming to definite conclusions foror against the preparation in essay paper the manufacturer possessesthe required information, but to obtain it from him takes time. Inother paper the manufacturer does not possess the information-- perhapshe did not realize the inadequacy of his evidence until the subject wasbrought to his attention by the council such paper might be dealt with in either one of two ways. The councilmight at once reject the article because the claims for it are notsupported by adequate evidence. Or, the council might suspend judgmentand give the manufacturer an opportunity to supply the information the first method-- immediate rejection-- would obviously be felt bymanufacturers as a hardship to afford the fullest possible opportunityfor the presentation of the case, the council follows the secondmethod. That is, it suspends judgment and withholds publication ofa report until reasonable time has been afforded for furnishing therequired information, provided the manufacturer or agent appears tobe making honest and diligent efforts to supply it the collectionand compilation of such information is essaytimes a lengthy process, especially when the products are of foreign manufacture although it would be easier for the council to render an immediatedecision than to assist manufacturers to supply the data necessary forthe formation of an authoritative judgment, the council cannot yield toimportunities for hasty action it must rely on the medical professionto bear in mind that the character of a product under considerationby the council has not yet been determined the council holds that, during this stage, a product is suitable, at most, for experimentaluse -- from reports of council on pharmacy and chemistry, 1915, p 119 cooperation of the pharmaceutical houses report of the council on pharmacy and chemistryin reply to the suggestion made last year by president bevan that thereshould be closer cooperation between the large pharmaceutical housesand the council on pharmacy and chemistry, the council submitted to theboard of trustees of the american medical association the statementwhich appears below. “cooperation of the pharmaceutical houses.

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Bromid of potassium, c p 40 grains bromid of sodium, c p 40 grains bromid of ammonium, c p 40 grains bromid of zinc 1 grain extract lupulin 32 grains cascara sagrada, fl ex 40 minims extract henbane 0 075 grain extract belladonna 0 075 grain extract cannabis indica 0 60 grain oil bitter almonds 0 60 grain aromatic elixirthis chemical blunderbuss was recommended for use in insomnia, hysteria, neurasthenia, migraine, neuralgia, delirium tremens, epilepsyand thesis other conditions also it was called an ideal calmative forchildren suffering from chorea, the exploiters claiming that “allauthorities recommend the bromids, hyoscyamus and cannabis indica inthis disease ” oliver t osborne, professor of therapeutics in yalemedical school, does not mention one of these three drugs in hisdiscussion of the medicinal treatment of chorea, in the handbook oftherapy, though he quotes several authorities in this article indeed, he does not mention one of the ten drugs included in the above formulaof neurosine in connection with the treatment of this disease it is acurious fact that osborne gives the greatest prominence to the use ofthat drug which is claimed to be wanting in the formula of neurosine, namely, hydrated chloral perhaps you may have seen temporary relief follow the administrationof neurosine in chorea, and may argue that theorizing is of littlevalue in the face of personal experience we shall not deny that essaymay have had that experience, for osborne calls attention to the factthat the success of any medicinal treatment must be judged in thelight of the fact that chorea is self-limited, and the intensity ofthe symptoms will abate in from two to four weeks in view of this, wewould hardly dispute the claim that one may administer narcotics, suchas those contained in neurosine, and the symptoms of chorea may abatein spite of such mistreatment in all the years that neurosine has beenexploited to physicians with such remarkable claims, we have never seena report of a careful clinical study in which the product has been usedunder the conditions which scientific investigation demands would youprescribe any nonproprietary preparations which had never been studiedclinically, if a horse-shoer or grocer boy told you it would cureepilepsy or malaria?. According to an editorial note appended to the report of the councilon neurosine, the dios chemical company consisted at that time 1915of j h chambers, his wife and two sons it appeared that chambersnever claimed to have any special knowledge of chemistry, pharmacy ormedicine, yet we find that he arrogated to himself or to his employeesthe right to offer therapeutic advice to the medical profession, andeven to direct them as to how they should prescribe a given mixture we essaytimes fail to see the forest because of the trees it may helpus to obtain a better perspective, in a problem that concerns usintimately, by resorting to a hypothetic case, if a close analogy ismaintained in order that we may see ourselves as others see us insuch a situation, let us consider the following imaginary case. Youbecome involved in a lawsuit in which an effort is made to deprive youof your property and your liberty you seek what you had reason tobelieve was competent legal advice. But, nevertheless, you lose yourcase and find yourself deprived of your property and your liberty nowlet us suppose further that you discover, when too late to permit youto correct your mistake, that your legal adviser we can hardly callsuch a man a lawyer had been acting all along under the guidance of aplumber who made no pretense of knowing anything about law how wouldyou feel regarding that pretended lawyer?. would you feel that you hadbeen treated fairly?. would you feel disposed to speak with all charityof him, to recommend him to those in need of legal advice?. You would probably feel toward such a lawyer as patients must feeltoward physicians who prescribe proprietary nostrums based oninformation and advice offered by those who, though without any specialknowledge of chemistry, pharmacy or medicine, will be benefitedfinancially if their information and advice are accepted and actedon -- from the journal a m a , april 27, 1918 anasarcin advertisingi i see index for other articles on anasarcin to the editor:-- as an old fellow of the a m a i beg to presentthe following facts to you, and to ask if anything can be done by youto expose the methods of these people. A concern calling itself “theanasarcin chem co ” of winchester, tenn , has caused to be sent tophysicians a chart on the subject of “diagnostics of renal diseases ”this chart contains eighteen plates, which were all taken withoutknowledge or permission of either myself or my publishers, williamwood & co , from the third edition of my book on “urinary analysisand diagnosis ” the plates are writingly composite plates, but mostlyportions of plates, exactly reproduced from my book i at once causedmy publishers to write to the anasarcin company.