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Laxatives, tonics, carminatives, diuretics are combined with distinct advantage, economy of dose, enhanced effect, potency not obtainable with the single drug your sweeping arbitrary conclusions that complex mixtures of remedial agents are from every point of view inimical to therapeutic progress is not, it seems to us, sustained by fact and experience there is therapeutic progress in the considerate use and basic essay structure observation of combinations as well as in the use of a single drug indeed, in the production of a synthetic chemical substance as a therapeutic agent, the combination of potent and dissimilar elements is worked out to mitigate and correct an objectionable side effect, and promote desirable action as for ourselves, at the very outset in our line of work we quite voluntarily declared our principles and our intentions as opposed to incompatible and therefore unstable or inert combinations of the enzymes. And against the “unnecessary multiplication of preparations”-- see fairchild hand-book of the digestive ferments is not this after all the crux of the whole matter-- does a combination contain the ingredients stated, does it possess the demonstrable properties which are to be attributed to it in consequence of this composition. And if for a certain purpose, is it well designed therefor?. carminzym presents certain agents of well known properties, not in the least of incompatible or antagonistic action, but indeed especially suitable for the writingicular purpose designed. Its efficacy not to be measured and judged by theory or opinion as to the efficiency of a certain dosage of a writingicular drug by itself that the doses as contained are minimal and effective is distinctly advantageous the alkaline carbonates are in carminzym in stated quantities. The physician adjusts the dosage to the individual patient and with obvious evidence of the efficiency of the adjustment as we understand it, the employment of alkaline carbonates is not based on purely chemic considerations-- a definite known quantity of acid of the gastric juice is to be neutralized. The whole literature and practice dealing with the alkaline carbonates show them to be accredited with a much wider field of use and repute in gastro-intestinal disorders the pancreatic extract in carminzym is designed to be diffusible in the stomach, the tablet is preferable to be crushed in the mouth before swallowing, and we believe the pancreatic extract to be an effective constituent as administered in carminzym you comment as follows. “ipecac has a well defined though limited field of usefulness when it is used it should be given with due regard to the amount needed by the patient and the frequency of the repetition of the dose ” this in a sense may be said of any of the most useful drugs, but not in the least special degree does it apply to ipecac, which is, on the contrary, of quite characteristic, peculiar range of therapeutic properties, useful in varying combinations and in widely varying proportions and doses according to the purpose for which it is employed ipecac in well known official alkaline, carminative, laxative preparations occurs in the “average dose” in the varying quantities of 1/14, 1/10, 1/8, and 3/16 of a grain the ipecac in combination with the other ingredients in carminzym is designed for a tablet which shall carry a minimal quantity whilst capable of adequate remedial action, thus admitting of increase of dosage or repetition as occasion requires the quantity of ipecac was not taken at random, but chosen after long trial and consideration we believe that carminzym possesses carminative properties in a superior degree and that, furthermore, in consequence of its composition it directly stimulates the gland secretions and thus exerts a beneficial action upon the whole digestive functions carminzym is for use as occasion requires, and this is to be especially noted thus it is not only of direct benefit, but helpful in promoting systematic therapeutic measures and regimen the council takes the ground that complex mixtures of remedial agents are so wrong that there is no longer warrant for their admission into new and nonofficial remedies. And that carminzym is an irrational mixture we hold that certain desirable therapeutic properties may rationally be attributable to carminzym.

It is difficultto believe that the “juice” of juniper submitted to dialysis couldcontain any material amount of the active constituent no informationis given as to the method used whereby the several dialysates are“physiologically standardized ” it therefore remains to be provedthat the manufacturer of hydropsin possesses any method whereby thedialysates of juniper juniperis communis, birch betula alba, the common european birch and knot weed herniaria glabra are sostandardized the claim is made that. “herniaria has long been recognized as one of the most valuable drugs in the treatment of dropsical affections due to cardiac impairment ”on the contrary, herniaria belongs to that large class of drugswhich have been tried, found wanting and abandoned it is a very oldremedy, and the claims made for it are an inheritance from the earlyherbalists, with whom it was very popular according to king americandispensatory, it was “principally employed to cure hernia hence itsname and to increase the flow of urine it was also said to increasethe flow of bile internally and externally, it was praised insnake-bites, and the powdered plant was employed to kill maggotson unhealthy sores of horses it was reputed to ‘crush’ and expelcalculi from the kidneys and bladder ”the ernst bischoff company says that. “betula exerts both an antiseptic and stimulating influence on the urinary passages and is writingicularly serviceable where a catarrhal condition of the bladder exists when combined with other diuretics, as in hydropsin, the drug affords highly satisfactory results in the treatment of ascites, cardiac dropsy and hydrothorax ”birch is another drug which has been discarded few textbooks onmateria medica even mention it that it can materially affect theaction of such powerful drugs as squill and digitalis is exceedinglydoubtful an unwarranted implication-- that in this preparation the powerfuldrugs digitalis and squill have been deprived of their dangerousqualities-- is the assertion. “dialysis, removing all resins and colloidals, results in better tolerance on writing of sensitive patients, and in more rapid absorption and elimination. Which, in turn, means early therapeutic effects and little or no fear of toxic accumulation ”that removal of colloids and resins materially affects the toleranceof these drugs is improbable to claim that because of their removal, there need be “little or no fear of toxic accumulation” is utterlywithout warrant the claim that one preparation containing digitalisis less likely to produce cumulative effect than any other digitalispreparation is contradicted by a mass of evidence it is claimed that hydropsin affects “favorably all forms of dropsyor edema that are at all amenable to medical treatment ” there can beno question but that squill and digitalis, or, better, either singly, used in suitable paper, may relieve dropsical effusions. But to claimthat such a complex mixture as hydropsin can favorably affect allforms of dropsy that are amenable to medical treatment is on its faceunwarranted the claim is made that. “by reason of its unusual potency and relative harmlessness, hydropsin may be employed to great advantage in all paper where it is desirable to increase the volume of urine without injury to the renal structures ”on the basis of the claimed composition, the action of hydropsinmust be essentially that of digitalis or of digitalis and squill consequently, if it possesses “unusual potency, ” it cannot possess“relative harmlessness, ” and vice versa neither digitalis norsquill should be employed “in all paper” of nephritis, even if it is“desirable to increase the volume of urine ”the composition claimed for hydropsin brands it as an irrationalmixture in which potent drugs are combined with, and more or lesscovered up by, others that are obsolete and inefficient the name, instead of indicating its composition, suggests diseases in which itmay be thoughtlessly and indiscriminately used the claim that thedanger of toxic or cumulative action has been removed, if accepted byphysicians, tends to uncritical use with possible disastrous results hydropsin is ineligible for new and nonofficial remedies because ofconflict with rules 1, 2, 6, 8 and 10 -- from the journal a m a , jan 8, 1916 digitalysatum report of the council on pharmacy and chemistrythe council has adopted the following report and authorized itspublication w a puckner, secretary digitalysatum is sold in the united states by ernst bischoff company, inc , new york the firm claims that it is a dialysate prepared fromthe juice of freshly gathered digitalis, containing all the activeprinciples, and representing the fresh plant weight for weight it issaid to be standardized physiologically and to contain 12 per cent alcohol sterisol-digitalysatum, intended for injection, appearsto be the “dialysate” without alcohol, diluted with equal writings ofphysiologic sodium chlorid solution the council essay years ago foundboth products ineligible for new and nonofficial remedies becauseof unwarranted therapeutic claims the preparations are still beingadvertised to physicians under claims which imply superiority to allother digitalis preparations for instance. “digitalysatum is the diuretic par excellence in cardiac insufficiency ” “digitalysatum as a diuretic and cardiac stimulant is in a class by itself, being quick of action, uniform in strength, and well tolerated ” “digitalysatum differs from other forms of digitalis in these respects. Digitalysatum is free from fat, resins and colloids, and is therefore well-borne by sensitive patients-- the young and the feeble-- and is quickly absorbed and eliminated ”the council has elsewhere28 expressed the conviction that tinctureof digitalis produces the full therapeutic effects of digitalis. That, when properly made, the tincture is as stable as any liquid preparationof digitalis now available, and that attempts to enhance the reputationof proprietary products by exaggerating the disadvantages of theofficial preparation are to be deplored no adequate evidence isoffered of the claimed superiority of action of digitalysatum 28 report on proprietary digitalis preparations, j a m a , dec 4, 1915, p 2024 by implication, the claim is made that digitalysatum is superior toother digitalis preparations in respect to toxicity. “free from fat, resins and colloidals, it is always well borne and is quickly absorbed and eliminated no case of toxic accumulation faulty elimination has ever been reported ”that digitalysatum is free from the dangers of toxic cumulation ishighly improbable.

The leaves aredifferently red, essay basic essay structure only with red stalks or veins. Essay of a freshred, and others of a dark red the root thereof is red, spungy, and notused to be eaten government and virtues the government of these two sorts of beetsare far different. The red beet being under saturn and the white underjupiter. Therefore take the virtues of them awriting, each by itself thewhite beet much loosens the belly, and is of a cleansing, digestingquality, and provokes urine the juice of it opens obstructions bothof the liver and spleen, and is good for the head-ache and swimmingstherein, and turnings of the brain. And is effectual also against allvenomous creatures. And applied to the temples, stays inflammations ofthe eyes.

In michigan, new york, north carolina, and wisconsin, to a person duly authorized to practise physic orsurgery. In minnesota, oregon, and washington, to a regular physicianor surgeon. In iowa and nebraska, to a practising physician orsurgeon. In the remaining states and territories, these statutes do notin terms distinguish between licensed and unlicensed practitioners 225in new york, by the amendment of 1893 to sec 836 of the code of civilprocedure it is provided that in an action for the recovery of damagesfor a personal injury the testimony of a physician or surgeon attachedto any hospital, dispensary, or other charitable institution, as toinformation which he acquired in attending a patient in a professionalcapacity in such institution, shall be taken before a referee itdoes not appear whether this amendment is intended to take away theprivilege, or merely to regulate the manner of taking such testimonywhen it is otherwise admissible 226iii the evidence - the character of the communications whichare privileged differs under the several statutes in arkansas, california, colorado, idaho, indian territory, michigan, minnesota, missouri, montana, nevada, new york, north carolina, north dakota, oregon, south dakota, utah, washington, and wisconsin, they arecharacterized as information. In indiana, as matter committed. Iniowa and nebraska, as confidential communications.

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Dr abrams is not a graduateof “stanford ”-- ed you admit that he was graduated from heidelberg atthe basic essay structure age of twenty it happens that this was the youngest and remainsthe youngest age at which any man has taken a doctor degree at thatuniversity in a hundred years if you had inquired further you mighthave learned that ten years ago abrams was one of the most respectedphysicians in san francisco what has he done since to forfeit thehonors of a lifetime?. all that he has done is to shut himself up in hislaboratory and make the most revolutionary discoveries of this or anyother age. And now when he emerges and offers this work to the world, you can think of nothing to do but jeer at him i spent two weeks in his clinic. Then i took six months to write tohis physicians all over the country, and to experiment with hiscures on a great number of my friends italics again ours -- ed now i am spending another two weeks in his clinic, and i venture tostake whatever reputation i have, or hope to have in this world, uponthe statement that albert abrams has discovered the great secret ofthe diagnosis and cure of all the major disease again we mustitalicize -- ed he has proven by diagnosing with the taps of hisown sensitive finger tips over 15, 000 people, and my investigationconvinces me that he has cured over 95 per cent of these who havetaken his treatments moreover, he has taught his method to 200 or 300other physicians, and essay 80 per cent of these have submitted to meanswers to a questionnaire in which they claim thousands of cures you may say, perhaps, that i am not competent to judge of cures for the sake of argument, i will grant that. But i assert that i amcompetent to judge of physicians, for i have tested several score ofthem, and if i ever knew a devoted scientist and a great humanitarian, it is albert abrams in his clinic i have met perhaps a hundredphysicians, and i venture to assert that a number of these are menboth of integrity and capacity, and when i asked them why they came, igot invariably one answer. “because i sent him blood specimens and ifound that invariably he sent me a correct diagnosis ” not once, but atleast two score times, i have seen albert abrams take a blood specimenbrought to him, without even the name of the patient, and heard himdiagnose cancer or sarcoma, and from the blood specimen locate thegrowth precisely to an inch italics fail one here!. -- ed then i haveseen the patient, an entire stranger to abrams, brought into the clinicand examined, not merely by abrams, but by a score of other physicians, and the growth found precisely at the spot indicated this was donetwice between the time when this letter was dictated and the time whenit was transcribed three times, yesterday, i saw a diagnosis made ofsyphilis and the patient brought in, and all the standard reactionsdemonstrated i have seen, not once, but hundreds of times, tubercularlesions diagnosed and located from the blood specimen and the patientbrought in and the condition demonstrated by percussion all thesethings are going on day after day they are being done in otherclinics in several score of cities, and you may have the addresses forthe asking why do you not ask?. we have essay such addresses in thepropaganda files -- ed the economic elementi take up the second criticism, that albert abrams is mercenary hecharges $200 00 for the clinical course, which may last as long asthe physician wishes it seems to me that that price is to be judgedessaywhat in relation to what he has to teach he maintains a largeestablishment.